Musculoskeletal Symptoms Predict Psoriatic Arthritis

This article originally appeared here.
Share this content:
Musculoskeletal Symptoms Predict Psoriatic Arthritis
Musculoskeletal Symptoms Predict Psoriatic Arthritis

MONDAY, March 13, 2017 (HealthDay News) -- For patients with psoriasis, nonspecific musculoskeletal symptoms, including joint pain, fatigue, and stiffness, predict the development of psoriatic arthritis (PsA), according to a study published in the March issue of Arthritis & Rheumatology.

Lihi Eder, M.D., Ph.D., from the University of Toronto, and colleagues conducted a prospective cohort study involving patients with psoriasis who were assessed at baseline and reassessed annually to examine development of clinical PsA. At each visit, the presence of musculoskeletal symptoms and the patients' assessments of pain, fatigue, stiffness, physical function, and psychological distress were recorded.

The researchers found that 57 of 410 patients with psoriasis developed PsA. Prediction of subsequent PsA was associated with baseline presence of arthralgia in women (hazard ratio [HR], 2.59), heel pain (HR, 4.18), high fatigue score (HR, 2.36), and high stiffness score (HR, 2.03). Increases from baseline in fatigue, pain, and stiffness scores (HRs, 1.27, 1.34, and 1.21, respectively), and a worsening in physical function score (HR, 0.96) also predicted PsA development.

"A preclinical phase exists in patients with PsA prior to the diagnosis of the disease," the authors write. "This phase is characterized by nonspecific musculoskeletal symptoms, including joint pain, fatigue, and stiffness."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

FDA Approves Admelog for Diabetes

FDA Approves Admelog for Diabetes

First drug approved as a follow-up product based on an abbreviated new process

High-Intensity Treadmill Exercise Feasible in Parkinson's Disease

High-Intensity Treadmill Exercise Feasible in Parkinson's Disease

Mean change in Unified Parkinson's Disease Rating Scale motor score lower for high-intensity exercise

is free, fast, and customized just for you!

Already a member?

Sign In Now »