Multi-Luminance Mobility Test Identifies Visual Impairment

This article originally appeared here.
Share this content:
Multi-Luminance Mobility Test Identifies Visual Impairment
Multi-Luminance Mobility Test Identifies Visual Impairment

TUESDAY, July 18, 2017 (HealthDay News) -- A multi-luminance mobility test (MLMT) can differentiate normal-sighted from visually-impaired subjects, according to a study published online July 11 in Clinical & Experimental Ophthalmology.

Daniel C. Chung, D.O., from Spark Therapeutics Inc. in Philadelphia, and colleagues conducted a prospective observational study involving 54 subjects (28 visually-impaired, 26 normal-sighted). Over one year, the subjects navigated MLMT courses three times; subjects completed testing using individual eyes and both eyes at up to nine standardized, increasing luminance levels at each visit. The authors compared accuracy and speed with visual acuity (VA), visual field (VF), and a visual function questionnaire.

The researchers found that normal-sighted subjects could be distinguished from visually-impaired subjects by MLMT. At all tested light levels, all control subjects passed all MLMT attempts; there was wide variation in visually-impaired subjects' performance, with some declining over one year. There was marked decline in performance below certain VA and VF thresholds. On two baseline visits there was high concordance on performance; for the lowest common and highest common lux levels, correlations for accuracy were 94 and 98 percent, respectively.

"MLMT differentiated visually-impaired from control populations, and, in visually-impaired subjects, identified a range of performances, and tracked performance declines over time, consistent with these progressive conditions," the authors write.

Several authors disclosed financial ties to CHOP and Spark Therapeutics; Spark Therapeutics partially funded the study. Several authors are inventors on a patent related to the MLMT.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

NAFLD Linked to Smaller Total Cerebral Brain Volume

NAFLD Linked to Smaller Total Cerebral Brain Volume

Significant correlation even after adjustment for all covariates, including age, sex, alcohol consumption

Salivary miRNAs Can ID Duration of Concussion Symptoms

Salivary miRNAs Can ID Duration of Concussion Symptoms

Pediatric patients with prolonged symptoms were accurately identified by levels of five miRNAs

Treatment Trajectories Vary for Children With Depression

Treatment Trajectories Vary for Children With Depression

Most common class got psychotherapy monotherapy, and had lowest incidence of attempted suicide

is free, fast, and customized just for you!

Already a member?

Sign In Now »