MRI May Help ID Suicide Risk in Young Bipolar Patients

Share this content:
MRI May Help ID Suicide Risk in Young Bipolar Patients
MRI May Help ID Suicide Risk in Young Bipolar Patients

TUESDAY, Jan. 31, 2017 (HealthDay News) -- Among adolescents and young adults with bipolar disorder, those who attempt suicide show reduced volume and activity in areas of the brain that regulate emotion and impulses, according to a study published online Jan. 31 in the American Journal of Psychiatry.

Using magnetic resonance imaging, Hilary Blumberg, M.D., of Yale University in New Haven, Conn., and colleagues compared regional gray matter volume, white matter integrity, and functional connectivity during processing of emotional stimuli in adolescents and young adults with bipolar disorder. Twenty six participants had a prior suicide attempt and 42 had no history of a suicide attempt.

The researchers found that, compared with those who had not attempted suicide, those who had attempted suicide exhibited significant reductions in gray matter volume in the orbitofrontal cortex, hippocampus, and cerebellum; white matter integrity in the uncinate fasciculus, ventral frontal, and right cerebellum regions; and amygdala functional connectivity to the left ventral and right rostral prefrontal cortex.

"The findings suggest that the frontal cortex is not working as well as it should to regulate the circuitry," Blumberg said in a Yale news release. "The identification of brain circuits involved in risk for suicide can lead to new ways to identify who is most at risk and, hopefully, prevent suicides."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »