MRI May Help ID Lewy Body Dementia Versus Alzheimer's

This article originally appeared here.
Share this content:
MRI May Help ID Lewy Body Dementia Versus Alzheimer's
MRI May Help ID Lewy Body Dementia Versus Alzheimer's

TUESDAY, Nov. 8, 2016 (HealthDay News) -- Magnetic resonance imaging (MRI) of the brain may aid diagnosis of dementia with Lewy bodies versus Alzheimer's disease, according to a study published online Nov. 2 in Neurology.

Starting in 2005, Kejal Kantarci, M.D., a radiologist at the Mayo Clinic in Rochester, Minn., and colleagues followed 160 patients with mild cognitive impairment. Participants had MRI brain scans to measure the size of the hippocampus. For an average of two years, study participants had annual evaluations. During the course of the study, 61 people developed Alzheimer's disease. Twenty people progressed to probable dementia with Lewy bodies.

The researchers found that someone whose hippocampus stayed the same size was nearly six times more likely to develop Lewy body dementia than someone whose hippocampus shrunk in size (hazard ratio, 5.8). A total of 17 of the 20 patients who were identified with probable Lewy body disease (85 percent) maintained normal volume in the hippocampus. Of the 61 participants who developed Alzheimer's, 37 (61 percent) had hippocampal atrophy.

"Identifying people with mild cognitive impairment at risk for dementia with Lewy bodies is critical for early interventions with the potential treatments emerging in the field," Kantarci told HealthDay. "Early diagnosis also helps target appropriate treatments, including what medications not to give. For example, as many as 50 percent of people with Lewy body disease have severe reactions to antipsychotic medications."

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

FDA Approves First Drug for Rare Form of Rickets

FDA Approves First Drug for Rare Form of ...

Crysvita approved for adults and children ages 1 year and older with x-linked hypophosphatemia

High FGF-23 Linked to Recurrent Cardiac Events After ACS

High FGF-23 Linked to Recurrent Cardiac Events After ...

FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization

Medical Cannabis Not Recommended for Sleep Apnea

Medical Cannabis Not Recommended for Sleep Apnea

American Academy of Sleep Medicine says evidence insufficient to recommend cannabis for apnea

is free, fast, and customized just for you!

Already a member?

Sign In Now »