Mortality, Second Stroke Risk Up for Initially Stable Survivors

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Mortality, Second Stroke Risk Up for Initially Stable Survivors
Mortality, Second Stroke Risk Up for Initially Stable Survivors

MONDAY, July 24, 2017 (HealthDay News) -- Risk of a second stroke or transient ischemic attack (TIA) remains considerable for at least five years after the first event, according to a study published online July 24 in CMAJ, the journal of the Canadian Medical Association.

Jodi Edwards, Ph.D., of the Sunnybrook Health Sciences Center in Toronto, and colleagues collected data on 26,366 stroke and TIA survivors without recurrent stroke, myocardial infarction, all-cause admission to hospital, admission to an institution, or death in the first 90 days after discharge. The researchers compared them with 263,660 healthy individuals matched by age, gender, and region. The team assessed the primary composite outcome of death, stroke, myocardial infarction, or admission to long-term or continuing care.

The investigators found that risk the primary outcome was increased at one, three, and five years (hazard ratios [HRs], 2.4, 2.2, and 2.1, respectively). The risks were highest for recurrent stroke at one year (HR, 6.8), continuing to five years (HR, 5.1), and for admission to an institution (HR, 2.1).

"Patients who survive stroke or TIA without early complications are typically discharged from secondary stroke prevention services. However, these patients remain at substantial long-term risk, particularly for recurrent stroke and admission to an institution," the authors write. "Novel approaches to prevention, potentially embedded in community or primary care, are required for long-term management of these initially stable but high-risk patients."

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