Monophasic HA Filler Noninferior to Biphasic for Nasolabial Folds

This article originally appeared here.
Share this content:
Monophasic HA Filler Noninferior to Biphasic for Nasolabial Folds
Monophasic HA Filler Noninferior to Biphasic for Nasolabial Folds

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Monophasic hyaluronic acid (HA) filler is safe and effective for correction of nasolabial folds (NLFs), according to a study published online Sept. 14 in the Journal of Cosmetic Dermatology.

Hyun Jung Kwon, M.D., from the Chung-Ang University College of Medicine in Seoul, South Korea, and colleagues compared the rheological properties, efficacy, and safety of a monophasic HA filler and a well-studied biphasic HA filler in 72 Korean subjects with moderate-to-severe NLFs. The Wrinkle Severity Rating Scale (WSRS) was used for assessments at two, 10, 18, 26, and 52 weeks.

The researchers found that at week 26, the mean WSRS score was 2.26 for the monophasic HA side and 2.24 for the biphasic HA side. Both treatments were well tolerated. Adverse reactions were mild and transient. Compared to the biphasic HA filler, the monophasic HA filler had lower elasticity and higher viscosity.

"Despite a number of different rheological properties, monophasic HA is noninferior to biphasic HA in the treatment of moderate-to-severe NLFs for 52 weeks," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

FDA Approves First Drug for Rare Form of Rickets

FDA Approves First Drug for Rare Form of ...

Crysvita approved for adults and children ages 1 year and older with x-linked hypophosphatemia

High FGF-23 Linked to Recurrent Cardiac Events After ACS

High FGF-23 Linked to Recurrent Cardiac Events After ...

FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization

Medical Cannabis Not Recommended for Sleep Apnea

Medical Cannabis Not Recommended for Sleep Apnea

American Academy of Sleep Medicine says evidence insufficient to recommend cannabis for apnea

is free, fast, and customized just for you!

Already a member?

Sign In Now »