Moms' Prior Flu Vaccine Doesn't Weaken Newborns' Benefit

Share this content:
Moms' Prior Flu Vaccine Doesn't Weaken Newborns' Benefit
Moms' Prior Flu Vaccine Doesn't Weaken Newborns' Benefit

FRIDAY, Aug. 4, 2017 (HealthDay News) -- Receipt of influenza vaccine the previous year predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains in pregnant women, according to a study published online Aug. 1 in Vaccine.

Lisa M. Christian, Ph.D., from The Ohio State University Wexner Medical Center in Columbus, and colleagues measured influenza antibody titers in 141 pregnant women via the hemagglutination inhibition assay prior to receipt of quadrivalent seasonal influenza vaccine, 30 days after vaccination, and at delivery, at which time cord blood titers were also measured.

The researchers found that, compared to the 50 women with no vaccination in the previous year, the 91 women vaccinated the prior year exhibited higher baseline antibody titers and/or seroprotection rates against all four influenza strains, after controlling for covariates. Lower peak antibody responses and seroconversion rates at one month after vaccination were also predicted by prior vaccination. There were no significant differences in antibody titers or seroprotection rates in women or newborns at delivery.

"In this cohort of pregnant women, receipt of influenza vaccine the previous year predicted higher baseline antibody titers and decreased peak antibody responses against all influenza strains," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters




More in Home

FDA Approves Palynziq for Phenylketonuria

FDA Approves Palynziq for Phenylketonuria

Drug is a novel enzyme therapy for adult patients with PKU with uncontrolled blood Phe concentrations

Increase in Tx Candidates With 2017 Hypertension Guidelines

Increase in Tx Candidates With 2017 Hypertension Guidelines

Increase in proportion of adults recommended for treatment; estimated decrease in CVD events, deaths