Moderate, Severe OSA Linked to Elevated Blood Coagulability

Share this content:
Moderate, Severe OSA Linked to Elevated Blood Coagulability
Moderate, Severe OSA Linked to Elevated Blood Coagulability

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Moderate and severe obstructive sleep apnea (OSA) are associated with elevated blood coagulability markers, according to a study published online Aug. 17 in JAMA Otolaryngology-Head & Neck Surgery.

Seung-No Hong, M.D., from the Korea University College of Medicine in Ansan, South Korea, and colleagues conducted a retrospective cohort study at a tertiary care university hospital involving 146 patients with OSA. Participants were classified according to OSA severity into control (41 patients), mild (32 patients), moderate (30 patients), and severe (43 patients) groups.

The researchers identified a significant correlation between the apnea-hypopnea index and the prothrombin time (PT) in seconds and as international normalized ratio (INR). Significant differences were identified in PT seconds for the control group versus the moderate and severe OSA groups (mean, 11.26 versus 10.74 and 10.67, respectively). There were also significant differences in PT INR for the control versus the moderate and severe OSA groups (1.00 versus 0.95 and 0.94, respectively). No significant difference was seen in PT seconds between the control and mild OSA groups.

"These results suggest that patients with moderate-to-severe OSA have elevated blood coagulability markers compared with healthy individuals, which may contribute to the occurrence of cardiovascular complications," the authors write.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

FDA OKs Nucala for Eosinophilic Granulomatosis With Polyangiitis

FDA OKs Nucala for Eosinophilic Granulomatosis With Polyangiitis

First drug to be approved for rare autoimmune disease that leads to vasculitis

Findings Support Individualized Glycemic Control in T2DM

Findings Support Individualized Glycemic Control in T2DM

Approach saved $13,547/patient vs uniform intensive control, with lower medication costs

Atherosclerosis ID'd in Many Without CV Risk Factors

Atherosclerosis ID'd in Many Without CV Risk Factors

LDL-C independently associated with the presence and extent of atherosclerosis

is free, fast, and customized just for you!

Already a member?

Sign In Now »