Mixed Results for Stem Cell Treatments of AMD

Share this content:
Mixed Results for Stem Cell Treatments of AMD
Mixed Results for Stem Cell Treatments of AMD

THURSDAY, March 16, 2017 (HealthDay News) -- Stem cells may offer new hope for patients with age-related macular degeneration, but that promise can come with some risks, according to research published in the March 17 issue of the New England Journal of Medicine.

One report details a legitimate effort to restore the sight of a 77-year-old Japanese woman with macular degeneration using stem cells. The team grafted a new sheet of retinal tissue derived from stem cells into the right eye of the female patient. One year after the operation, the patient's vision stabilized and her eye appears to have accepted the graft with no serious side effects, the authors reported.

A second article in the same journal issue reports on three older women who underwent unproven stem cell treatments on their eyes in 2015, senior author Jeffrey Goldberg, M.D., Ph.D., chair of ophthalmology for the Byers Eye Institute at Stanford University in Palo Alto, Calif., told HealthDay. The women all thought the stem cell therapy was part of a clinical trial, but there's no evidence that a genuine clinical trial was taking place, Goldberg noted.

"The patients' severe visual loss after the injection was associated with ocular hypertension, hemorrhagic retinopathy, vitreous hemorrhage, combined traction and rhegmatogenous retinal detachment, or lens dislocation," write the authors of the second report. "After one year, the patients' visual acuity ranged from 20/200 to no light perception."

Abstract/Full Text 1 (subscription or payment may be required)
Abstract/Full Text 2 (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters




More in Home

FDA Approves Palynziq for Phenylketonuria

FDA Approves Palynziq for Phenylketonuria

Drug is a novel enzyme therapy for adult patients with PKU with uncontrolled blood Phe concentrations

Increase in Tx Candidates With 2017 Hypertension Guidelines

Increase in Tx Candidates With 2017 Hypertension Guidelines

Increase in proportion of adults recommended for treatment; estimated decrease in CVD events, deaths