Metformin Tied to Cardiovascular Benefits in T1DM Patients

Share this content:
Metformin Tied to Cardiovascular Benefits in T1DM Patients
Metformin Tied to Cardiovascular Benefits in T1DM Patients

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Metformin may help preserve cardiovascular health in patients with type 1 diabetes, according to a study published online Aug. 26 in Cardiovascular Diabetology.

The new study included 23 adults with type 1 diabetes who were treated with metformin for eight weeks, 23 healthy age- and sex-matched volunteers without type 1 diabetes, and nine patients with type 1 diabetes who weren't given metformin.

The researchers saw a number of markers indicating blood vessel repair improve in patients taking metformin. The team noted improvements in circulating endothelial progenitor cells, colony forming units-Hill's colonies, circulating endothelial cells, and pro-angiogenic cell count and function, and deemed the effects independent of hypoglycemic effect.

"We have shown -- both in test tube and in patients -- the mechanism behind the cardioprotective effects of metformin," senior author Jolanta Weaver, Ph.D., of Newcastle University in the United Kingdom, told HealthDay. "This is likely to lead to the development of new drugs for heart disease in diabetes."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Clinician Awareness of Exercise Addiction May Be Lacking

Clinician Awareness of Exercise Addiction May Be Lacking

Screening questions should focus on emotional connection to exercise, whether it interferes with life

Overall Vagotomy Not Linked to Risk of Parkinson's Disease

Overall Vagotomy Not Linked to Risk of Parkinson's ...

But there is a trend toward lower risk of Parkinson's for patients with truncal vagotomy

Pediatricians Missing Elevated Blood Lead Levels in U.S.

Pediatricians Missing Elevated Blood Lead Levels in U.S.

In 23 of 39 reporting states, pediatric care providers identified fewer than half of children with EBLL

is free, fast, and customized just for you!

Already a member?

Sign In Now »