Memory Scores Limited As Alzheimer's Screening Tool

Share this content:
Memory Scores Limited As Alzheimer's Screening Tool
Memory Scores Limited As Alzheimer's Screening Tool

MONDAY, Dec. 4, 2017 (HealthDay News) -- Low memory scores are an early marker of amyloid positivity, but have limited value as a screening measure for early Alzheimer's disease among persons without dementia, according to a study published online Nov. 29 in JAMA Psychiatry.

Willemijn J. Jansen, Ph.D., from Maastricht University in the Netherlands, and colleagues investigated whether amyloid-β aggregation is associated with cognitive functioning based on analysis of 2,908 participants with normal cognition and 4,133 with mild cognitive impairment (MCI).

The researchers found that among participants with normal cognition, amyloid positivity was associated with low memory scores after age 70 years, but was not associated with low Mini-Mental State Examination (MMSE) scores (P = 0.16). Among patients with MCI, amyloid positivity was associated with both low memory (P < 0.001) and low MMSE (P < 0.001) scores. This association decreased with age. There was limited utility for screening of amyloid positivity in persons with normal cognition or those with MCI based on low cognitive scores.

"Although low memory scores are an early marker of amyloid positivity, their value as a screening measure for early Alzheimer's disease among persons without dementia is limited," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Gender Difference in Survival Seen After Radical Cystectomy

Gender Difference in Survival Seen After Radical Cystectomy

Females have worse disease-free, cancer-specific, overall survival versus males with bladder cancer

Adult Obesity Prevalence Varies With Level of Urbanization

Adult Obesity Prevalence Varies With Level of Urbanization

Increased obesity for men, women living in medium, small versus large metropolitan statistical areas

Attitudes Among Obese Are Not Aligned With Healthy Living

Attitudes Among Obese Are Not Aligned With Healthy ...

Consumers with obesity report favoring taste and value rather than health and nutrition

is free, fast, and customized just for you!




Already a member?

Sign In Now »