Medication Organization Devices Tied to Adverse Effects

Share this content:
Medication Organization Devices Tied to Adverse Effects
Medication Organization Devices Tied to Adverse Effects

MONDAY, July 11, 2016 (HealthDay News) -- Medication organization devices (MODs) may cause medication-related adverse events in unintentionally nonadherent older people, according to a study published online July 5 in Health Technology Assessment.

Debi Bhattacharya, Ph.D., from the University of East Anglia in the United Kingdom, and colleagues conducted a systematic review and focus groups with patients, caregivers, and health care professionals to inform the design of a randomized controlled trial to evaluate clinical effectiveness and cost-effectiveness of MODs. The study design was evaluated using participants who were older than 75 years and prescribed at least three solid oral dosage form medications.

The researchers found that MOD studies are largely of poor quality and that the relationship between adherence and health outcomes is unclear. The pre-trial focus groups altered the planned study design by suggesting a minimum recruitment age of 50 to 60 years. Of the patients who completed the baseline questionnaire, 35.4 percent were excluded because of pre-existing use of an MOD. The rate of intentional nonadherence was 24.7 percent. Of the remaining 76 participants, 46.1 percent were unintentionally nonadherent. In the MOD study arms, five adverse/serious adverse events were reported, compared with none in the control arms.

"A study examining the association between MOD initiation and adverse effects is necessary and a strategy to safely introduce MODs should be explored," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Recent Decline in Prescription Opioid Use Among U.S. Teens

Recent Decline in Prescription Opioid Use Among U.S. ...

Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Treatment Seeking Low Among Teens With Eating Disorders

Treatment Seeking Low Among Teens With Eating Disorders

Those with counter-stereotypic presentation even less likely to seek treatment

Optical Clearing Agent Ups No. of Laser Passes in Tattoo Removal

Optical Clearing Agent Ups No. of Laser Passes ...

Findings based on number of laser passes during a five-minute tattoo removal session

is free, fast, and customized just for you!

Already a member?

Sign In Now »