Mechanical Thrombectomy Benefits Large Vessel Occlusion

Share this content:
Mechanical Thrombectomy Benefits Large Vessel Occlusion
Mechanical Thrombectomy Benefits Large Vessel Occlusion

FRIDAY, Dec. 4, 2015 (HealthDay News) -- For patients with acute ischemic stroke caused by large artery occlusion, mechanical thrombectomy after usual care is associated with improved outcomes versus usual care alone, according to a review published in the Dec. 8 issue of the Journal of the American College of Cardiology.

Islam Y. Elgendy, M.D., from the University of Florida in Gainesville, and colleagues conducted a systematic review to examine whether mechanical thrombectomy after usual care correlates with better outcomes in patients with acute ischemic stroke caused by large artery occlusion. Data were included from nine trials, with 2,410 patients.

The researchers found that mechanical thrombectomy correlated with a higher incidence of achieving good functional outcome, defined as a modified Rankin scale (mRS) of 0 to 2, (risk ratio [RR], 1.45; 95 percent confidence interval [CI], 1.22 to 1.72) and excellent functional outcome (mRS 0 to 1; RR, 1.67; 95 percent CI, 1.27 to 2.19) at 90 days, compared with usual care (both P < 0.0001). Mechanical thrombectomy correlated with a trend toward reduced all-cause mortality (RR, 0.86; 95 percent CI, 0.72 to 1.02; P = 0.09). With either treatment modality the risk of symptomatic intracranial hemorrhage was similar (RR 1.06; 95 percent CI, 0.73 to 1.55; P = 0.76).

"Mechanical thrombectomy after usual care was associated with improved functional outcomes compared with usual care alone, and was found to be relatively safe, with no excess in intracranial hemorrhage," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »