May 2017 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Self-Pay for Obesity Treatment Doesn't Improve Weight Loss

WEDNESDAY, May 31, 2017 (HealthDay News) -- For individuals in a weight management program, paying out-of-pocket is not associated with a significant difference in weight loss compared to that seen for employees with insurance coverage, according to a report published online May 24 in Obesity.

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Diabetic Foot Ulcers, Infections Significantly Up Burden of Care

WEDNESDAY, May 31, 2017 (HealthDay News) -- Diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs) are associated with increased risks of admission and outpatient visits, according to a study published online May 11 in Diabetes Care.

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Social Psychology May Help With Physician Error Disclosure

TUESDAY, May 30, 2017 (HealthDay News) -- Lessons from social psychology can be used to improve behavioral changes in terms of error disclosure, according to research published online May 18 in Medical Education.

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High-Risk Pools May Represent Step Back for U.S. Health Care

TUESDAY, May 30, 2017 (HealthDay News) -- Proposed legislation as part of the American Health Care Act, which includes the option of high-risk pools, is not likely to reduce costs, according to an Ideas and Opinions piece published online May 23 in the Annals of Internal Medicine.

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Breaking Up Sedentary Time With Upper Body Activity Beneficial

TUESDAY, May 30, 2017 (HealthDay News) -- For obese adults, performing short bouts of arm ergometry during prolonged sitting is associated with reduced mean blood glucose and insulin incremental area under the curve (iAUC), according to a study published online May 23 in Diabetes, Obesity and Metabolism.

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Increased Gut Diversity Seen After Roux-en-Y

TUESDAY, May 30, 2017 (HealthDay News) -- Roux-en-Y gastric bypass surgery triggers major changes in the microbial population of the digestive tract, according to a report published online May 26 in the ISME Journal.

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Deceased Diabetic Donor Kidneys Feasible for Transplantation

FRIDAY, May 26, 2017 (HealthDay News) -- Kidneys from deceased donors who had diabetes can save the lives of patients on the transplant wait-list, according to a study published online May 25 in the Clinical Journal of the American Society of Nephrology.

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New Health Care Act Could Result in 23 Million Losing Insurance

FRIDAY, May 26, 2017 (HealthDay News) -- The Republican-led bill to repeal and replace the Affordable Care Act (ACA) that passed the House this month would result in 23 million Americans losing their health insurance coverage, according to a report issued by the Congressional Budget Office (CBO).

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New Bill Intends to Repeal Limits on Physician-Owned Hospitals

FRIDAY, May 26, 2017 (HealthDay News) -- A new bill introduced in the U.S. House of Representatives would repeal the federal law essentially banning construction of physician-owned hospitals and making it difficult for these facilities to grow, according to a report published by the American Medical Association (AMA).

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Targeting ANGPTL3 Can Significantly Lower Cholesterol

FRIDAY, May 26, 2017 (HealthDay News) -- Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block the angiopoietin-like 3 (ANGPTL3) gene. The findings were published online May 24 in the New England Journal of Medicine.

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Location of Body Fat Can Indicate Obesity-Related Cancer Risk

THURSDAY, May 25, 2017 (HealthDay News) -- Both body mass index (BMI) and location of excess body fat on the body are good indicators of obesity-related cancer risk, according to a meta-analysis published online April 25 in the British Journal of Cancer.

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New Interactive Module Aims to Clarify Professional Boundaries

THURSDAY, May 25, 2017 (HealthDay News) -- A new interactive training module in medical ethics can help physicians to understand professional boundaries, according to a report published by the American Medical Association (AMA).

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Orthostatic Hypotension in T2DM Linked to Riser Type Circadian BP

THURSDAY, May 25, 2017 (HealthDay News) -- For patients with type 2 diabetes, orthostatic hypotension (OH) is associated with riser patterns in the blood pressure (BP) circadian rhythm, as well as increased rates of mortality and major adverse cardiac and cerebrovascular events, according to a study published online May 11 in the Journal of Diabetes Investigation.

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Mapping IDs Geographic Access Barriers for Diabetic Retinopathy

THURSDAY, May 25, 2017 (HealthDay News) -- Geographic information systems mapping can visualize geographic access barriers to eye care among patients with diabetes, while telescreening can increase the rate of diabetes retinopathy evaluation, according to two studies published online May 18 in JAMA Ophthalmology.

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Path to Empathy Deemed As Vital As Being Empathetic

THURSDAY, May 25, 2017 (HealthDay News) -- Different paths to perspective of another's experience are associated with varying effect on helpers' health during helping behavior, according to a study published online April 16 in the Journal of Experimental Social Psychology.

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Normal Meal Tolerance Test Is Practical, Reliable in T2DM

WEDNESDAY, May 24, 2017 (HealthDay News) -- A normal meal tolerance test (NMTT) -- a simplified version of the mixed meal tolerance test -- is valuable as an insulin secretion test in patients with type 2 diabetes, with exception of those in a hyperglycemic state, according to a study published online May 11 in the Journal of Diabetes Investigation.

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Patients With Polyneuropathy More Often Receive Opioids

TUESDAY, May 23, 2017 (HealthDay News) -- Polyneuropathy is associated with increased likelihood of receiving long-term opioids, although long-term opioids do not improve functional status markers, according to a study published online May 22 in JAMA Neurology.

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Statin Therapy Found to Be of Little Benefit in Older Adults

TUESDAY, May 23, 2017 (HealthDay News) -- The benefit of pravastatin for primary prevention in older adults with moderate hyperlipidemia and hypertension is questionable, according to a study published online May 22 in JAMA Internal Medicine.

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Patients Often Prescribed Futile Drugs in Last Months of Life

MONDAY, May 22, 2017 (HealthDay News) -- Patients with life-limiting illness often receive medications of questionable benefit given their remaining life span, according to a report published online May 15 in The American Journal of Medicine.

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Nine of Ten Practices Surveyed Have Dismissed Patients

MONDAY, May 22, 2017 (HealthDay News) -- The majority of medical practices have dismissed patients, according to a research letter published online May 15 in JAMA Internal Medicine.

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No Link to Cognition in Diabetes Prevention Program Study

MONDAY, May 22, 2017 (HealthDay News) -- For participants in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS), exposure to metformin or lifestyle intervention is not associated with cognition, according to research published online May 12 in Diabetes Care.

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Eating More Fruits, Vegetables May Lower Risk of PAD

FRIDAY, May 19, 2017 (HealthDay News) -- Eating plenty of fruits and vegetables may help reduce the risk of peripheral artery disease (PAD), according to a study published online May 18 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Glucose Peaks Linked to Cognitive Decline, Dementia in Diabetes

FRIDAY, May 19, 2017 (HealthDay News) -- Glucose peaks are associated with cognitive decline and dementia among individuals with diabetes, according to a study published online May 12 in Diabetes Care.

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Tips Provided to Help Physicians Plan for Retirement

THURSDAY, May 18, 2017 (HealthDay News) -- Physicians should consider their retirement and plan ahead at all stages of their career, according to an article published in Medical Economics.

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Promising Start for National Diabetes Prevention Program

THURSDAY, May 18, 2017 (HealthDay News) -- The National Diabetes Prevention Program (DPP) has achieved widespread implementation of the lifestyle change portion to help prevent type 2 diabetes, according to a study published online May 12 in Diabetes Care.

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FDA Warns of Amputation Risk Associated With Canagliflozin

WEDNESDAY, May 17, 2017 (HealthDay News) -- The type 2 diabetes medication canagliflozin (brand names Invokana, Invokamet, Invokamet XR) appears to increase the risk of leg and foot amputations, the U.S. Food and Drug Administration says.

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Treatment in Hospital by Older Doctors Tied to Higher Mortality

WEDNESDAY, May 17, 2017 (HealthDay News) -- Hospitalized patients 65 and older may face a slightly higher risk of dying within a month of their admittance when treated by an older versus younger physician, according to research published online May 16 in The BMJ.

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CDC: Slowing of Decline in Number of Uninsured Adults

WEDNESDAY, May 17, 2017 (HealthDay News) -- The decline in the number of Americans without health insurance stalled in 2016 after five years of progress, according to a U.S. Centers for Disease Control and Prevention report released Tuesday.

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Telemedical Lifestyle Intervention Ups T2DM Glycemic Control

WEDNESDAY, May 17, 2017 (HealthDay News) -- A Telemedical Lifestyle Intervention Program (TeLiPro) can improve glycemic control in advanced-stage type 2 diabetes, according to a study published online May 12 in Diabetes Care.

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Body Size Linked to Primary Hyperparathyroidism in Women

WEDNESDAY, May 17, 2017 (HealthDay News) -- Body size seems to be associated with increased risk of primary hyperparathyroidism (P-HPTH) in women, according to a study published online May 10 in the Journal of Bone and Mineral Research.

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Plan Suggested for Reducing Health Care Costs

TUESDAY, May 16, 2017 (HealthDay News) -- Health care costs can be reduced, with a nine-step plan suggested as a starting place, according to an article published in Medical Economics.

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Warmer Temperatures May Up Risk of Gestational Diabetes

TUESDAY, May 16, 2017 (HealthDay News) -- Outdoor air temperature may influence a pregnant woman's risk of developing gestational diabetes, according to a study published online May 15 in CMAJ, the journal of the Canadian Medical Association.

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Pharmacist-Involved Collaborative Care Benefits T2DM

MONDAY, May 15, 2017 (HealthDay News) -- Multidisciplinary collaborative care with pharmacist follow-up is beneficial for Asian patients with uncontrolled type 2 diabetes, according to a study published online April 27 in the Journal of Clinical Pharmacy and Therapeutics.

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Hospitals Need to Be Prepared for Ransomware Attacks

FRIDAY, May 12, 2017 (HealthDay News) -- Hackers are increasingly targeting hospitals, using viruses to lock their computer systems and hold sensitive medical data and other files hostage, according to an observation piece published online May 11 in The BMJ.

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Activation of Estrogen Receptor α-AF1 May Target Adiposity

FRIDAY, May 12, 2017 (HealthDay News) -- Selective activation of estrogen receptor α (ERα) activation function-1 (AF1) prevents obesity, steatosis, and insulin resistance in a mouse model, according to an experimental study published online May 11 in The American Journal of Pathology.

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Never Breastfeeding Linked to Increased Risk of T1DM

FRIDAY, May 12, 2017 (HealthDay News) -- Never breastfeeding seems to be associated with increased risk of type 1 diabetes, according to a study published online May 9 in Diabetes Care.

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Bioengineered Intraabdominal Endocrine Pancreas Feasible

THURSDAY, May 11, 2017 (HealthDay News) -- In a research letter published in the May 11 issue of the New England Journal of Medicine, scientists report a step forward in the plan to create a truly artificial pancreas, offering new hope to patients with type 1 diabetes.

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Practice Prices Linked to Some Measures of Care Coordination

THURSDAY, May 11, 2017 (HealthDay News) -- High-price practices have higher scores on certain measures of care coordination and management, but the overall relationship between higher prices and quality and efficiency of care is weak, according to a report published in the May issue of Health Affairs.

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Patients Satisfied With Telehealth Primary Care Visits

THURSDAY, May 11, 2017 (HealthDay News) -- Patients express satisfaction with telehealth primary care video visits, with most reporting interest in continuing use of video visits as an alternative to in-person visits, according to a study published in the May/June issue of the Annals of Family Medicine.

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Outpatient Wait Times Are Longer for Medicaid Recipients

THURSDAY, May 11, 2017 (HealthDay News) -- Medicaid patients have slightly longer waits at medical appointments than those with private insurance, according to a report published in the May issue of Health Affairs.

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Biomarker ID'd for Pregnancy-Induced Glucose Intolerance

THURSDAY, May 11, 2017 (HealthDay News) -- One measurement of plasma glycated CD59 (pGCD59) in pregnancy can predict glucose intolerance, according to a study published online May 3 in Diabetes Care.

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Increases in Rates of Insured Don't Harm Continuously Insured

WEDNESDAY, May 10, 2017 (HealthDay News) -- Increases in insurance coverage from 2008 to 2014 were not associated with worse access to care for continuously insured adults, according to a study published in the May issue of Health Affairs.

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Vitamin D Doesn't Impact Insulin Sensitivity, Secretion in T2DM

WEDNESDAY, May 10, 2017 (HealthDay News) -- For patients with type 2 diabetes (T2D) and vitamin D deficiency, vitamin D supplementation has no impact on insulin sensitivity or secretion, according to a study published online May 3 in Diabetes Care.

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Postmarket Safety Events for 32 Percent of Novel Therapeutics

WEDNESDAY, May 10, 2017 (HealthDay News) -- From 2001 to 2010, 32 percent of novel therapeutics approved by the U.S. Food and Drug Administration had a postmarket safety event, according to a study published in the May 9 issue of the Journal of the American Medical Association.

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USPSTF Does Not Recommend Routine Thyroid Cancer Screening

TUESDAY, May 9, 2017 (HealthDay News) -- Clinicians should not routinely screen adults for thyroid cancer if they have no symptoms or warning signs of the disease, according to a final recommendation statement issued by the U.S. Preventative Services Task Force and published in the May 9 issue of the Journal of the American Medical Association.

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Evidence-Based Medicine Course Beneficial for Critical Thinking

TUESDAY, May 9, 2017 (HealthDay News) -- An evidence-based medicine (EBM) course has some positive effect on medical student critical thinking (CT), according to a study published online April 27 in the Journal of Evidence-Based Medicine.

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PCSK9 Linked to New-Onset Diabetes After Renal Transplant

TUESDAY, May 9, 2017 (HealthDay News) -- For renal transplant recipients (RTRs) without diabetes, circulating proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with new-onset diabetes after transplantation (NODAT), according to a study published online May 1 in Diabetes Care.

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Most Physician Mothers Report Perceived Discrimination

TUESDAY, May 9, 2017 (HealthDay News) -- A considerable proportion of physician mothers report perceived discrimination, according to a research letter published online May 8 in JAMA Internal Medicine.

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Only 10 Percent of Daily Salt Intake Comes From Shaker

TUESDAY, May 9, 2017 (HealthDay News) -- Most of the salt that Americans consume comes from processed foods and restaurant meals, according to a report published in the May 9 issue of Circulation.

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Geographic Disparities Seen for Longevity in the United States

MONDAY, May 8, 2017 (HealthDay News) -- Life expectancy can differ by as much as two decades between various U.S. counties, according to research published online May 8 in JAMA Internal Medicine.

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More Women Than Men Leaving Practice of Medicine

MONDAY, May 8, 2017 (HealthDay News) -- More women than men leave the practice of medicine, according to an article published in Medical Economics.

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Linear Association for Weight Loss, HbA1c Reduction in T2DM

MONDAY, May 8, 2017 (HealthDay News) -- For overweight and obese adults with type 2 diabetes (T2D), weight loss is associated with a reduction in hemoglobin A1c (HbA1c) in a dose-dependent manner, according to a review published online April 18 in Diabetes, Obesity and Metabolism.

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Weight-Loss Behavioral Program Beneficial for Adults

FRIDAY, May 5, 2017 (HealthDay News) -- A weight-management group behavioral program is more effective than an intervention comprising brief advice and self-help materials, according to a study published online May 3 in The Lancet.

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Case Report Describes Insulin Autoimmune Syndrome

FRIDAY, May 5, 2017 (HealthDay News) -- In a case report published online May 1 in Diabetes Care, resolution of hypoglycemia and cardiovascular dysfunction after rituximab treatment of insulin autoimmune syndrome is described.

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Nocebo Effect Reported for Statin Therapy Use

FRIDAY, May 5, 2017 (HealthDay News) -- The rate of muscle-related adverse event (AE) reports is increased when patients and their doctors are aware that statins are being used, according to a study published online May 2 in The Lancet.

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More Side Effects With CRT Plus Metformin in Head, Neck Cancer

FRIDAY, May 5, 2017 (HealthDay News) -- Patients with advanced head and neck cancer undergoing chemoradiotherapy (CRT) and receiving metformin experience more side effects than patients not on metformin, according to research published online April 27 in Head & Neck.

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Poll: Many Americans Concerned About ACA Repeal

THURSDAY, May 4, 2017 (HealthDay News) -- Only one in five Americans support a repeal of the Affordable Care Act (ACA), a new HealthDay/Harris Poll reveals.

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Stair Walking Combats Fatigue Better Than Caffeine

THURSDAY, May 4, 2017 (HealthDay News) -- Easy stair walking may boost energy more effectively than drinking caffeine, according to research published online recently in Physiology & Behavior.

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CMS Releases Resources to Help With Payment System

THURSDAY, May 4, 2017 (HealthDay News) -- The Centers for Medicare & Medicaid Services (CMS) recently added three new online resources to assist physicians already participating in the Merit-based Incentive Payment System (MIPS) and those exploring the opportunities available.

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Lower Incidence of Chronic Illness for Centenarians

THURSDAY, May 4, 2017 (HealthDay News) -- Among elderly veterans, the incidence of chronic illness is lower for centenarians than octogenarians and nonagenarians, according to a study published online April 19 in the Journal of the American Geriatrics Society.

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Teprotumumab More Effective Than Placebo for Ophthalmopathy

THURSDAY, May 4, 2017 (HealthDay News) -- A human monoclonal antibody inhibitor of insulin-like growth factor I receptor, teprotumumab, is more effective than placebo for patients with thyroid-associated ophthalmopathy, according to a study published in the May 4 issue of the New England Journal of Medicine.

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Cardiometabolic Disease Staging Score Quantifies Diabetes Risk

THURSDAY, May 4, 2017 (HealthDay News) -- For overweight and obese individuals, the Cardiometabolic Disease Staging (CMDS) score can quantify the risk of diabetes and predict the effectiveness of weight-loss therapy for preventing diabetes, according to research published online April 28 in Diabetes Care.

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H2 Injection Aids Diabetes Outcomes in Animal Model

WEDNESDAY, May 3, 2017 (HealthDay News) -- Subcutaneous injection of H2 significantly improves type 2 diabetes mellitus (T2DM)-related outcomes in a mouse model, according to a study published online April 8 in the Journal of Diabetes Investigation.

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Half of U.S. Doctors Receive Payments From Industry

WEDNESDAY, May 3, 2017 (HealthDay News) -- About half of U.S. doctors received payments from the pharmaceutical and medical device industries in 2015, amounting to $2.4 billion, and any form or amount of compensation can influence prescribing behavior, according to research published in the May 2 issue of the Journal of the American Medical Association, a theme issue on conflict of interest.

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CDC: Mortality Rate for Black Americans Drops 25 Percent

WEDNESDAY, May 3, 2017 (HealthDay News) -- While the overall mortality rate among black Americans dropped 25 percent between 1999 and 2015, the average life expectancy still lags behind whites by almost four years, according to research published in the May 2 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Optimal Cardiovascular Health in Middle Age Adds Years to Life

TUESDAY, May 2, 2017 (HealthDay News) -- Individuals with optimal cardiovascular health in middle age live an average of four years longer than their peers who have at least two risk factors for cardiovascular disease, and almost five years longer free of chronic disease, according to a study published in the May 2 issue of Circulation.

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Too Few Americans Know the Warning Signs of Stroke

TUESDAY, May 2, 2017 (HealthDay News) -- About 35 percent of Americans experience symptoms of a transient ischemic attack (TIA), yet only 3 percent get immediate medical attention, according to findings from the American Heart Association/American Stroke Association.

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Alternate-Day Fasting Not More Effective for Weight Loss

TUESDAY, May 2, 2017 (HealthDay News) -- Alternate-day fasting does not produce superior weight loss or weight maintenance compared with daily calorie restriction, according to a study published online May 1 in JAMA Internal Medicine.

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Combo of Exercise, Vitamin D May Boost Effects on Heart Health

TUESDAY, May 2, 2017 (HealthDay News) -- Physical activity and vitamin D appear to have synergistic beneficial effects on the risk of atherosclerotic cardiovascular disease, according to a study published in the April 1 issue of the Journal of Clinical Endocrinology & Metabolism.

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Aging Substantially Ups Risk for Needing Help With Money, Meds

TUESDAY, May 2, 2017 (HealthDay News) -- Many seniors over age 85 need help with finances and/or managing their medications, according to research published online April 5 in the Journal of the American Geriatrics Society.

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Intense Interval Training Cuts Hypoglycemia Awareness in T1DM

TUESDAY, May 2, 2017 (HealthDay News) -- For patients with type 1 diabetes and normal awareness of hypoglycemia (NAH), high-intensity interval training (HIIT) is associated with reduced awareness of subsequent hypoglycemia, according to a study published online April 18 in Diabetes.

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Screen Size, Shape Affect User Perception of Smartwatches

MONDAY, May 1, 2017 (HealthDay News) -- Large screens are more effective for promoting the hedonic (perceived attractiveness) and pragmatic (perceived control) qualities of smartwatches, while round and square screens are associated with hedonic and pragmatic quality, respectively, according to a study published online April 21 in the Journal of Computer Mediated Communication.

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Decreased Cortical Thickness Seen in Type 2 Diabetes

MONDAY, May 1, 2017 (HealthDay News) -- Patients with type 2 diabetes mellitus (T2DM) -- particularly those who are overweight or obese -- have decreased cortical thickness in several areas of the brain, according to research published online April 27 in Diabetologia.

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