May 2017 Briefing - Cardiology

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Here are what the editors at HealthDay consider to be the most important developments in Cardiology for May 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Self-Pay for Obesity Treatment Doesn't Improve Weight Loss

WEDNESDAY, May 31, 2017 (HealthDay News) -- For individuals in a weight management program, paying out-of-pocket is not associated with a significant difference in weight loss compared to that seen for employees with insurance coverage, according to a report published online May 24 in Obesity.

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Distinct Maternal, Fetal Risks for Anticoagulants in Pregnancy

WEDNESDAY, May 31, 2017 (HealthDay News) -- Anticoagulation for mechanical heart valves during pregnancy is associated with distinct maternal and fetal risks, according to a review published in the June 6 issue of the Journal of the American College of Cardiology.

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Evacetrapib Appears Futile in High-Risk Vascular Disease

WEDNESDAY, May 31, 2017 (HealthDay News) -- For patients with high-risk vascular disease, evacetrapib does not affect the primary efficacy end point of first occurrence of any component of a composite of death from cardiovascular causes, myocardial infarction, stroke, coronary revascularization, or hospitalization for unstable angina, according to a study published in the May 18 issue of the New England Journal of Medicine.

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Social Psychology May Help With Physician Error Disclosure

TUESDAY, May 30, 2017 (HealthDay News) -- Lessons from social psychology can be used to improve behavioral changes in terms of error disclosure, according to research published online May 18 in Medical Education.

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Cessation of Meth Abuse Linked to Reversal of Heart Damage

TUESDAY, May 30, 2017 (HealthDay News) -- With proper medical treatment, it may be possible to reverse heart damage in methamphetamine users who stop using the drug, according to a study published in the June 1 issue of JACC: Heart Failure.

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Breaking Up Sedentary Time With Upper Body Activity Beneficial

TUESDAY, May 30, 2017 (HealthDay News) -- For obese adults, performing short bouts of arm ergometry during prolonged sitting is associated with reduced mean blood glucose and insulin incremental area under the curve (iAUC), according to a study published online May 23 in Diabetes, Obesity and Metabolism.

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Reduced Cellular Aging Seen With Regular, Strenuous Exercise

TUESDAY, May 30, 2017 (HealthDay News) -- People who consistently engage in high levels of physical activity have longer telomeres than those who have sedentary lifestyles, as well as those who are moderately active, according to a study scheduled for publication in the July issue of Preventive Medicine.

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High-Risk Pools May Represent Step Back for U.S. Health Care

TUESDAY, May 30, 2017 (HealthDay News) -- Proposed legislation as part of the American Health Care Act, which includes the option of high-risk pools, is not likely to reduce costs, according to an Ideas and Opinions piece published online May 23 in the Annals of Internal Medicine.

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New Bill Intends to Repeal Limits on Physician-Owned Hospitals

FRIDAY, May 26, 2017 (HealthDay News) -- A new bill introduced in the U.S. House of Representatives would repeal the federal law essentially banning construction of physician-owned hospitals and making it difficult for these facilities to grow, according to a report published by the American Medical Association (AMA).

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New Health Care Act Could Result in 23 Million Losing Insurance

FRIDAY, May 26, 2017 (HealthDay News) -- The Republican-led bill to repeal and replace the Affordable Care Act (ACA) that passed the House this month would result in 23 million Americans losing their health insurance coverage, according to a report issued by the Congressional Budget Office (CBO).

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Factors Raise Risk of Pregnancy-Related Stroke in Preeclampsia

FRIDAY, May 26, 2017 (HealthDay News) -- Several factors raise the risk of pregnancy-related stroke in women with preeclampsia, according to a study published online May 25 in Stroke.

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Targeting ANGPTL3 Can Significantly Lower Cholesterol

FRIDAY, May 26, 2017 (HealthDay News) -- Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block the angiopoietin-like 3 (ANGPTL3) gene. The findings were published online May 24 in the New England Journal of Medicine.

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New Interactive Module Aims to Clarify Professional Boundaries

THURSDAY, May 25, 2017 (HealthDay News) -- A new interactive training module in medical ethics can help physicians to understand professional boundaries, according to a report published by the American Medical Association (AMA).

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Remission Up for Mepolizumab in Eosinophilic Granulomatosis

THURSDAY, May 25, 2017 (HealthDay News) -- Mepolizumab is associated with significantly more weeks in remission than placebo among patients with eosinophilic granulomatosis with polyangiitis, according to a study published in the May 18 issue of the New England Journal of Medicine.

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Path to Empathy Deemed As Vital As Being Empathetic

THURSDAY, May 25, 2017 (HealthDay News) -- Different paths to perspective of another's experience are associated with varying effect on helpers' health during helping behavior, according to a study published online April 16 in the Journal of Experimental Social Psychology.

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Orthostatic Hypotension in T2DM Linked to Riser Type Circadian BP

THURSDAY, May 25, 2017 (HealthDay News) -- For patients with type 2 diabetes, orthostatic hypotension (OH) is associated with riser patterns in the blood pressure (BP) circadian rhythm, as well as increased rates of mortality and major adverse cardiac and cerebrovascular events, according to a study published online May 11 in the Journal of Diabetes Investigation.

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Reducing Caloric Intake Appears to Slow Biological Aging

WEDNESDAY, May 24, 2017 (HealthDay News) -- Limiting calorie intake may slow aging, according to a study published online May 22 in the Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.

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Regular Chocolate Consumption May Lower Risk of A-Fib

WEDNESDAY, May 24, 2017 (HealthDay News) -- Regular chocolate consumption may lead to a lower risk of atrial fibrillation (AF), according to research published online May 23 in Heart.

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Mortality Rates Found Lower at Major Teaching Hospitals

WEDNESDAY, May 24, 2017 (HealthDay News) -- Older adults treated at major teaching facilities are less likely to die in the weeks and months following their discharge than patients admitted to community hospitals, according to research published in the May 23/30 issue of the Journal of the American Medical Association.

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Statin Therapy Found to Be of Little Benefit in Older Adults

TUESDAY, May 23, 2017 (HealthDay News) -- The benefit of pravastatin for primary prevention in older adults with moderate hyperlipidemia and hypertension is questionable, according to a study published online May 22 in JAMA Internal Medicine.

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Risk Up for Triple Tx Versus DAPT in DES Implantation With A-Fib

TUESDAY, May 23, 2017 (HealthDay News) -- For patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES), atrial fibrillation (AF) is associated with increased risks, with no benefit and higher risk seen for triple therapy compared to dual antiplatelet therapy (DAPT), according to a study published online May 17 in JACC: Cardiovascular Interventions.

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Poverty Affects Severity of Organ Damage Due to Lupus

MONDAY, May 22, 2017 (HealthDay News) -- Poverty and race are tied to the health of lupus patients in the United States, according to two new studies.

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Patients Often Prescribed Futile Drugs in Last Months of Life

MONDAY, May 22, 2017 (HealthDay News) -- Patients with life-limiting illness often receive medications of questionable benefit given their remaining life span, according to a report published online May 15 in The American Journal of Medicine.

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Nine of Ten Practices Surveyed Have Dismissed Patients

MONDAY, May 22, 2017 (HealthDay News) -- The majority of medical practices have dismissed patients, according to a research letter published online May 15 in JAMA Internal Medicine.

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Eating More Fruits, Vegetables May Lower Risk of PAD

FRIDAY, May 19, 2017 (HealthDay News) -- Eating plenty of fruits and vegetables may help reduce the risk of peripheral artery disease (PAD), according to a study published online May 18 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Similar Outcomes for Bivalirudin, Heparin in STEMI With PCI

FRIDAY, May 19, 2017 (HealthDay News) -- Similar outcomes are seen for use of bivalirudin and heparin as anticoagulant agents in patients with ST-segment elevation myocardial infarction (STEMI) treated with radial primary percutaneous coronary intervention (PCI), according to a study published online May 17 in JACC: Cardiovascular Interventions.

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Beetroot Juice Can Reduce Central Sympathetic Outflow

FRIDAY, May 19, 2017 (HealthDay News) -- Acute dietary nitrate supplementation using beetroot (BR) juice can decrease central sympathetic outflow at rest and during exercise, according to a study published online May 5 in the American Journal of Physiology-Heart and Circulatory Physiology.

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Tips Provided to Help Physicians Plan for Retirement

THURSDAY, May 18, 2017 (HealthDay News) -- Physicians should consider their retirement and plan ahead at all stages of their career, according to an article published in Medical Economics.

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Global Burden of Cardiovascular Disease Assessed

THURSDAY, May 18, 2017 (HealthDay News) -- Cardiovascular disease (CVD) is a major global burden, despite declines in the mortality rate due to CVD in high-income and some middle-income countries, according to a study published online May 17 in the Journal of the American College of Cardiology.

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Most Routine Coagulation Tests Reliable Up to Eight Hours

THURSDAY, May 18, 2017 (HealthDay News) -- Most routine coagulation tests can be reliably evaluated after storage at room temperature for up to eight hours after blood collection, according to a study published online May 8 in the International Journal of Laboratory Hematology.

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Treatment in Hospital by Older Doctors Tied to Higher Mortality

WEDNESDAY, May 17, 2017 (HealthDay News) -- Hospitalized patients 65 and older may face a slightly higher risk of dying within a month of their admittance when treated by an older versus younger physician, according to research published online May 16 in The BMJ.

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Acute MI Risk Significantly Up Following Respiratory Infection

WEDNESDAY, May 17, 2017 (HealthDay News) -- The risk of acute myocardial infarction (AMI) increases sharply after a respiratory infection, according to a study published in the May issue of the Internal Medicine Journal.

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CDC: Slowing of Decline in Number of Uninsured Adults

WEDNESDAY, May 17, 2017 (HealthDay News) -- The decline in the number of Americans without health insurance stalled in 2016 after five years of progress, according to a U.S. Centers for Disease Control and Prevention report released Tuesday.

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HRT Not Advised for Disease Prevention Post Menopause

WEDNESDAY, May 17, 2017 (HealthDay News) -- Using hormone therapy to prevent chronic health issues, such as cardiovascular disease and bone loss, in postmenopausal women may do more harm than good, the U.S. Preventive Services Task Force (USPSTF) says.

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Iron Rx Doesn't Improve Exercise Capacity in Iron-Deficient HFrEF

TUESDAY, May 16, 2017 (HealthDay News) -- Oral iron supplementation doesn't improve the exercise capacity of iron-deficient patients with heart failure with reduced left ventricular ejection fraction (HFrEF), according to a study published in the May 16 issue of the Journal of the American Medical Association.

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Plan Suggested for Reducing Health Care Costs

TUESDAY, May 16, 2017 (HealthDay News) -- Health care costs can be reduced, with a nine-step plan suggested as a starting place, according to an article published in Medical Economics.

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Younger Age at Menopause Tied to Higher Risk of Heart Failure

TUESDAY, May 16, 2017 (HealthDay News) -- Women who undergo menopause early or who never gave birth might have an increased risk of heart failure, according to a study published in the May 23 issue of the Journal of the American College of Cardiology.

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Findings Support More Targeted Approach to Cholesterol Screens

TUESDAY, May 16, 2017 (HealthDay News) -- The prevalence of elevated cardiovascular risk is low in normotensive, nonsmoking women younger than 50 years and men younger than 40 years, according to a study published online May 16 in the Annals of Internal Medicine.

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Warning Against Domperidone Use for Lactating Women

MONDAY, May 15, 2017 (HealthDay News) -- The dopamine receptor antagonist domperidone, which may increase milk production in lactating women, is associated with serious cardiac risks, and should not be used for lactation enhancement, according to a commentary published in the June issue of Obstetrics and Gynecology.

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Hospitals Need to Be Prepared for Ransomware Attacks

FRIDAY, May 12, 2017 (HealthDay News) -- Hackers are increasingly targeting hospitals, using viruses to lock their computer systems and hold sensitive medical data and other files hostage, according to an observation piece published online May 11 in The BMJ.

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Practice Prices Linked to Some Measures of Care Coordination

THURSDAY, May 11, 2017 (HealthDay News) -- High-price practices have higher scores on certain measures of care coordination and management, but the overall relationship between higher prices and quality and efficiency of care is weak, according to a report published in the May issue of Health Affairs.

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New VTE Often Occurs During Chemo in Ovarian Cancer

THURSDAY, May 11, 2017 (HealthDay News) -- For patients with ovarian cancer, new diagnosis of venous thromboembolism frequently occurs during neoadjuvant or adjuvant chemotherapy, according to a study published in the June issue of Obstetrics and Gynecology.

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Outpatient Wait Times Are Longer for Medicaid Recipients

THURSDAY, May 11, 2017 (HealthDay News) -- Medicaid patients have slightly longer waits at medical appointments than those with private insurance, according to a report published in the May issue of Health Affairs.

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AAN: Families Should Ask About Body Cooling After Cardiac Arrest

THURSDAY, May 11, 2017 (HealthDay News) -- Therapeutic hypothermia should be utilized to minimize the risk of brain damage for cardiac arrest patients in a coma, according to a new guideline published online May 10 in Neurology.

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Outcomes Up With Same Hospital Readmissions in Heart Failure

THURSDAY, May 11, 2017 (HealthDay News) -- Heart failure patients who are readmitted to the same hospital after their initial treatment are more likely to survive compared to those treated at a different hospital, according to research published online May 10 in the Journal of the American Heart Association.

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Patients Satisfied With Telehealth Primary Care Visits

THURSDAY, May 11, 2017 (HealthDay News) -- Patients express satisfaction with telehealth primary care video visits, with most reporting interest in continuing use of video visits as an alternative to in-person visits, according to a study published in the May/June issue of the Annals of Family Medicine.

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Initiation of NSAID Use Associated With Risk of Acute MI

WEDNESDAY, May 10, 2017 (HealthDay News) -- Nonsteroidal anti-inflammatory drugs (NSAIDs) increase the risk of acute myocardial infarction (MI) by 20 to 50 percent, with elevated risk as early as the first week of use, according to a report published online May 9 in The BMJ.

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Increases in Rates of Insured Don't Harm Continuously Insured

WEDNESDAY, May 10, 2017 (HealthDay News) -- Increases in insurance coverage from 2008 to 2014 were not associated with worse access to care for continuously insured adults, according to a study published in the May issue of Health Affairs.

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Postmarket Safety Events for 32 Percent of Novel Therapeutics

WEDNESDAY, May 10, 2017 (HealthDay News) -- From 2001 to 2010, 32 percent of novel therapeutics approved by the U.S. Food and Drug Administration had a postmarket safety event, according to a study published in the May 9 issue of the Journal of the American Medical Association.

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Clinical Benefits for CRT-D Over ICD Even With Comorbidity

WEDNESDAY, May 10, 2017 (HealthDay News) -- For patients with left bundle branch block, the benefit of cardiac resynchronization therapy with defibrillator (CRT-D) over implantable cardioverter-defibrillator (ICD) alone persists with comorbidity, according to a study published in the May 16 issue of the Journal of the American College of Cardiology.

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Evidence-Based Medicine Course Beneficial for Critical Thinking

TUESDAY, May 9, 2017 (HealthDay News) -- An evidence-based medicine (EBM) course has some positive effect on medical student critical thinking (CT), according to a study published online April 27 in the Journal of Evidence-Based Medicine.

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Most Physician Mothers Report Perceived Discrimination

TUESDAY, May 9, 2017 (HealthDay News) -- A considerable proportion of physician mothers report perceived discrimination, according to a research letter published online May 8 in JAMA Internal Medicine.

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Only 10 Percent of Daily Salt Intake Comes From Shaker

TUESDAY, May 9, 2017 (HealthDay News) -- Most of the salt that Americans consume comes from processed foods and restaurant meals, according to a report published in the May 9 issue of Circulation.

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Geographic Disparities Seen for Longevity in the United States

MONDAY, May 8, 2017 (HealthDay News) -- Life expectancy can differ by as much as two decades between various U.S. counties, according to research published online May 8 in JAMA Internal Medicine.

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More Women Than Men Leaving Practice of Medicine

MONDAY, May 8, 2017 (HealthDay News) -- More women than men leave the practice of medicine, according to an article published in Medical Economics.

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Research Supports Pulmonary Benefits for ACEIs, ARBs

MONDAY, May 8, 2017 (HealthDay News) -- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) might play an important role in the prevention and treatment of emphysema, according to a study published in the May 1 issue of the Annals of the American Thoracic Society.

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Even 'Social Smoking' Negatively Affects Cardiovascular Health

FRIDAY, May 5, 2017 (HealthDay News) -- Social smokers have the same risk for hypertension and elevated cholesterol as regular smokers do, according to a study published online May 2 in the American Journal of Health Promotion.

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Weight-Loss Behavioral Program Beneficial for Adults

FRIDAY, May 5, 2017 (HealthDay News) -- A weight-management group behavioral program is more effective than an intervention comprising brief advice and self-help materials, according to a study published online May 3 in The Lancet.

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Disability Reduced When Bystander CPR Is Performed

FRIDAY, May 5, 2017 (HealthDay News) -- Quick action from bystanders can have a long-lasting impact for patients with cardiac arrest, according to a study published in the May 4 issue of the New England Journal of Medicine.

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E-Health-Based Management of Oral Anticoagulation Tx Beneficial

FRIDAY, May 5, 2017 (HealthDay News) -- Electronic-health-based management of oral anticoagulation (OAC) therapy is associated with fewer adverse events, according to a study published online April 29 in the Journal of Thrombosis and Haemostasis.

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Nocebo Effect Reported for Statin Therapy Use

FRIDAY, May 5, 2017 (HealthDay News) -- The rate of muscle-related adverse event (AE) reports is increased when patients and their doctors are aware that statins are being used, according to a study published online May 2 in The Lancet.

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Case Report Describes Insulin Autoimmune Syndrome

FRIDAY, May 5, 2017 (HealthDay News) -- In a case report published online May 1 in Diabetes Care, resolution of hypoglycemia and cardiovascular dysfunction after rituximab treatment of insulin autoimmune syndrome is described.

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Poll: Many Americans Concerned About ACA Repeal

THURSDAY, May 4, 2017 (HealthDay News) -- Only one in five Americans support a repeal of the Affordable Care Act (ACA), a new HealthDay/Harris Poll reveals.

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Stair Walking Combats Fatigue Better Than Caffeine

THURSDAY, May 4, 2017 (HealthDay News) -- Easy stair walking may boost energy more effectively than drinking caffeine, according to research published online recently in Physiology & Behavior.

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CMS Releases Resources to Help With Payment System

THURSDAY, May 4, 2017 (HealthDay News) -- The Centers for Medicare & Medicaid Services (CMS) recently added three new online resources to assist physicians already participating in the Merit-based Incentive Payment System (MIPS) and those exploring the opportunities available.

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Lower Incidence of Chronic Illness for Centenarians

THURSDAY, May 4, 2017 (HealthDay News) -- Among elderly veterans, the incidence of chronic illness is lower for centenarians than octogenarians and nonagenarians, according to a study published online April 19 in the Journal of the American Geriatrics Society.

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Ischemic Outcomes Don't Vary With Gender in ACS Patients

THURSDAY, May 4, 2017 (HealthDay News) -- For acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) and receiving clopidogrel, prasugrel, or ticagrelor, ischemic outcome does not differ by gender, according to a study published online April 29 in Cardiovascular Therapeutics.

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Gluten-Free Diet Not Healthy for Patients Without Celiac Disease

WEDNESDAY, May 3, 2017 (HealthDay News) -- Going gluten-free when there's no medical need to do so won't boost cardiovascular health -- and might even harm it, according to a study published online May 2 in The BMJ.

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Angiography Beneficial for Management of Unstable Angina

WEDNESDAY, May 3, 2017 (HealthDay News) -- Use of routine invasive coronary angiography is beneficial for management of patients with unstable angina, according to a study published online May 1 in the Annals of Internal Medicine.

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Low Use of Medications, Lifestyle Counseling in PAD Patients

WEDNESDAY, May 3, 2017 (HealthDay News) -- Patients with peripheral artery disease (PAD) have low use of medication therapy and lifestyle counseling, according to a study published in the May 9 issue of the Journal of the American College of Cardiology.

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Half of U.S. Doctors Receive Payments From Industry

WEDNESDAY, May 3, 2017 (HealthDay News) -- About half of U.S. doctors received payments from the pharmaceutical and medical device industries in 2015, amounting to $2.4 billion, and any form or amount of compensation can influence prescribing behavior, according to research published in the May 2 issue of the Journal of the American Medical Association, a theme issue on conflict of interest.

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CDC: Mortality Rate for Black Americans Drops 25 Percent

WEDNESDAY, May 3, 2017 (HealthDay News) -- While the overall mortality rate among black Americans dropped 25 percent between 1999 and 2015, the average life expectancy still lags behind whites by almost four years, according to research published in the May 2 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Optimal Cardiovascular Health in Middle Age Adds Years to Life

TUESDAY, May 2, 2017 (HealthDay News) -- Individuals with optimal cardiovascular health in middle age live an average of four years longer than their peers who have at least two risk factors for cardiovascular disease, and almost five years longer free of chronic disease, according to a study published in the May 2 issue of Circulation.

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Too Few Americans Know the Warning Signs of Stroke

TUESDAY, May 2, 2017 (HealthDay News) -- About 35 percent of Americans experience symptoms of a transient ischemic attack (TIA), yet only 3 percent get immediate medical attention, according to findings from the American Heart Association/American Stroke Association.

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Alternate-Day Fasting Not More Effective for Weight Loss

TUESDAY, May 2, 2017 (HealthDay News) -- Alternate-day fasting does not produce superior weight loss or weight maintenance compared with daily calorie restriction, according to a study published online May 1 in JAMA Internal Medicine.

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Aging Substantially Ups Risk for Needing Help With Money, Meds

TUESDAY, May 2, 2017 (HealthDay News) -- Many seniors over age 85 need help with finances and/or managing their medications, according to research published online April 5 in the Journal of the American Geriatrics Society.

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Combo of Exercise, Vitamin D May Boost Effects on Heart Health

TUESDAY, May 2, 2017 (HealthDay News) -- Physical activity and vitamin D appear to have synergistic beneficial effects on the risk of atherosclerotic cardiovascular disease, according to a study published in the April 1 issue of the Journal of Clinical Endocrinology & Metabolism.

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Von Willebrand Factor Multimers Predict Regurgitation in TAVR

TUESDAY, May 2, 2017 (HealthDay News) -- Assessment of defects in high-molecular-weight (HMW) multimers of von Willebrand factor or point-of-care assessment of hemostasis can monitor aortic regurgitation during transcatheter aortic-valve replacement (TAVR), according to a study published recently in the New England Journal of Medicine.

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Mechanical Thrombectomy Safe in Older Ischemic Stroke Patients

MONDAY, May 1, 2017 (HealthDay News) -- For older adults with acute ischemic stroke, endovascular therapy seems safe and efficacious, according to a study published online April 19 in the Journal of the American Geriatrics Society.

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Screen Size, Shape Affect User Perception of Smartwatches

MONDAY, May 1, 2017 (HealthDay News) -- Large screens are more effective for promoting the hedonic (perceived attractiveness) and pragmatic (perceived control) qualities of smartwatches, while round and square screens are associated with hedonic and pragmatic quality, respectively, according to a study published online April 21 in the Journal of Computer Mediated Communication.

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