May 2016 Briefing - Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for May 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Approves Ocaliva for Primary Biliary Cholangitis

TUESDAY, May 31, 2016 (HealthDay News) -- Ocaliva (obeticholic acid) has been approved by the U.S. Food and Drug Administration to treat primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

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Possible Benefit Found for Betrixaban in Acutely Ill

TUESDAY, May 31, 2016 (HealthDay News) -- Betrixaban may be beneficial versus enoxaparin in acutely ill medical patients, according to a study published online May 27 in the New England Journal of Medicine. The research was published to coincide with the annual meeting of the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee, held from May 25 to 28 in Montpellier, France.

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AHRQ Communication Toolkit Can Help After Patient Harm Occurs

TUESDAY, May 31, 2016 (HealthDay News) -- A new communication toolkit created by the Agency for Healthcare Research and Quality (AHRQ) can help health care organizations and providers communicate with patients and families when harm occurs to patients.

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Cephalexin Failure Rate Similar for Morbidly Obese, Non-Obese

TUESDAY, May 31, 2016 (HealthDay News) -- For patients receiving cephalexin monotherapy for non-purulent cellulitis, the rate of therapeutic failure does not differ for morbidly obese and non-obese, according to a study published online May 19 in the Journal of Clinical Pharmacy and Therapeutics.

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DAPT Score Improves Risk Prediction of Continued DAPT

TUESDAY, May 31, 2016 (HealthDay News) -- A decision tool (dual antiplatelet therapy [DAPT] score) improves risk prediction for continued DAPT beyond assessment of myocardial infarction (MI) history, according to a study published in the May 31 issue of the Journal of the American College of Cardiology.

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Glucocorticoid Use Ups Diabetes Risk in Rheumatoid Arthritis

TUESDAY, May 31, 2016 (HealthDay News) -- For patients with rheumatoid arthritis (RA), glucocorticoid treatment is associated with increased risk of diabetes mellitus (DM), according to a study published in the May issue of Arthritis & Rheumatology.

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U.S. Has First Documented Case of Superbug Resistant to Colistin

FRIDAY, May 27, 2016 (HealthDay News) -- The first case of a patient infected with a superbug resistant to a last-resort antibiotic has been documented in the United States. The report was published online May 26 in Antimicrobial Agents and Chemotherapy.

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Intermittent Steroids Reduce Some Asthma Exacerbations

FRIDAY, May 27, 2016 (HealthDay News) -- There is strong evidence to support intermittent inhaled corticosteroids (ICS) for prevention of wheeze exacerbations in preschool children with intermittent asthma or viral-triggered wheezing, according to a review published online May 26 in Pediatrics.

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Prednisone Use Linked to Increased Risk of Mortality in RA

FRIDAY, May 27, 2016 (HealthDay News) -- For patients with rheumatoid arthritis (RA), prednisone use is associated with an increased risk of mortality, according to a study published in the May issue of Arthritis Care & Research.

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PPI Use Ups NSAID-Induced Small Bowel Injury

FRIDAY, May 27, 2016 (HealthDay News) -- Proton pump inhibitors (PPIs) increase the risk of nonsteroidal anti-inflammatory drug-induced small bowel injury, according to a study published in the June issue of Clinical Gastroenterology and Hepatology.

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Remaining Uninsured May Be Difficult to Reach Via ACA

FRIDAY, May 27, 2016 (HealthDay News) -- Uninsurance rates have decreased since the introduction of the Affordable Care Act (ACA), but reaching the remaining uninsured may prove challenging, according to a health policy brief published online May 23 in Health Affairs.

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Triptorelin Doesn't Prevent Chemo-Induced Ovarian Failure

FRIDAY, May 27, 2016 (HealthDay News) -- Triptorelin plus norethisterone (GnRHa) does not prevent chemotherapy-induced premature ovarian failure (POF) in young patients with lymphoma, according to a study published online May 23 in the Journal of Clinical Oncology.

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Recognition of Patient Expertise Can Improve Adherence

FRIDAY, May 27, 2016 (HealthDay News) -- Recognizing the unique role of patients and their expertise within the physician-patient interaction can help to prevent non-adherence based on disagreement, according to an article published online May 18 in the Journal of Evaluation in Clinical Practice.

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New Findings Offer Hope for Those With Severe Hemophilia

THURSDAY, May 26, 2016 (HealthDay News) -- Two new studies could pave the way to major changes in how severe cases of hemophilia are treated. Both studies were published in the May 26 issue of the New England Journal of Medicine.

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Many Americans Have Reservations About Clinical Trials

WEDNESDAY, May 25, 2016 (HealthDay News) -- Just four in 10 Americans have a positive impression of clinical trials, and only about one-third of Americans would be likely to enroll in one, according to a study commissioned by the Memorial Sloan Kettering Cancer Center in New York City.

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Many Antidepressant Scripts Written for Off-Label Purpose

WEDNESDAY, May 25, 2016 (HealthDay News) -- Depression accounts for only a little more than half the antidepressant prescriptions issued by Quebec physicians during the past decade, and two out of every three non-depression prescriptions are for an off-label purpose, according to a research letter published in the May 24/31 issue of the Journal of the American Medical Association.

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Chemotherapy Toxicity Predictive Model Validated

WEDNESDAY, May 25, 2016 (HealthDay News) -- A predictive model for chemotherapy toxicity has been validated for older patients with solid tumors, according to a study published online May 16 in the Journal of Clinical Oncology.

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Lip Cancer Risk Up for Some Solid Organ Transplant Recipients

TUESDAY, May 24, 2016 (HealthDay News) -- For solid organ transplant recipients, azathioprine dose and duration of immunosuppression are associated with increased risk of lip cancer, according to a study published in the June issue of the Journal of the American Academy of Dermatology.

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Metformin Combats Adipose Tissue Expansion Via AMPK

TUESDAY, May 24, 2016 (HealthDay News) -- AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1 (TGF-β1), according to a study published online May 13 in Diabetes.

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AAP Recommends at Least One Full-Time Nurse in Every School

MONDAY, May 23, 2016 (HealthDay News) -- Every school should have at least one full-time registered nurse, according to a new American Academy of Pediatrics (AAP) policy statement published online May 23 in Pediatrics.

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Women Battling Cancer Need More Fertility Preservation Info

MONDAY, May 23, 2016 (HealthDay News) -- Many young female cancer survivors say they don't receive enough information about preserving their fertility, according to a study published online May 23 in Cancer.

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Some Sun Protection Behaviors Up With History of NMSC

MONDAY, May 23, 2016 (HealthDay News) -- Individuals with previous nonmelanoma skin cancer (NMSC) are more likely to engage in certain sun protection behaviors than those without previous NMSC, according to a study published online May 16 in the Journal of the American Academy of Dermatology.

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Opioid Prescriptions Drop for First Time in Two Decades

MONDAY, May 23, 2016 (HealthDay News) -- In a sign that the opioid epidemic might be waning, new data show that the number of opioid prescriptions has dropped for the first time in 20 years.

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Two New Drugs Added to Heart Failure Clinical Practice Guideline

MONDAY, May 23, 2016 (HealthDay News) -- An updated clinical guideline adds two new types of drugs to the list of treatment options for heart failure. The updated guideline was published online May 20 in the Journal of the American College of Cardiology, Circulation, and the Journal of Cardiac Failure.

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Major Stroke May Be Prevented by Taking Aspirin After TIA

FRIDAY, May 20, 2016 (HealthDay News) -- Taking aspirin immediately after a transient ischemic attack (TIA) significantly reduces the risk of a major stroke, according to research published online May 18 in The Lancet.

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Danazol Treatment Linked to Telomere Elongation

FRIDAY, May 20, 2016 (HealthDay News) -- In patients with telomere diseases, treatment with the synthetic sex hormone danazol is associated with telomere elongation, according to a study published in the May 18 issue of the New England Journal of Medicine.

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Sulfonylureas May Inhibit KATP Channel Neuroprotection

FRIDAY, May 20, 2016 (HealthDay News) -- Treatment with sulfonylureas (ATP-sensitive potassium [KATP] channel blockers) may inhibit the neuroprotective effects of KATP channel activation and increase the risk of stroke, according to an experimental study published online May 13 in Diabetes.

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FDA Approves Tecentriq to Treat Urothelial Carcinoma

THURSDAY, May 19, 2016 (HealthDay News) -- The U.S. Food and Drug Administration has approved atezolizumab (Tecentriq), a PD-1/PD-L1 inhibitor, for treatment of patients with locally-advanced or metastatic urothelial carcinoma whose disease has worsened during or following platinum-containing chemotherapy, or within 12 months of receiving platinum-containing chemotherapy, either before or after surgery.

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Strategies Can Help Streamline Revenue-Related Processes

THURSDAY, May 19, 2016 (HealthDay News) -- Strategies can be employed to maximize the amount of time available for patient care by streamlining revenue-related processes, according to the American Medical Association (AMA).

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Pregabalin in Pregnancy Linked to Increased Risk of Birth Defects

THURSDAY, May 19, 2016 (HealthDay News) -- The widely prescribed drug pregabalin (Lyrica) may slightly increase the risk for birth defects, according to a study published online May 18 in Neurology.

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Nocturnal Hypoglycemia Often Occurs in Children With T1DM

THURSDAY, May 19, 2016 (HealthDay News) -- Nocturnal hypoglycemia frequently occurs in children with type 1 diabetes, and is mainly asymptomatic, according to a research letter published online May 13 in Diabetes Care.

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Unrealistic Expectations for Many Men With Localized Prostate CA

THURSDAY, May 19, 2016 (HealthDay News) -- Men with localized prostate cancer (LPC) often have unrealistic survival expectations, according to a study published in the May/June issue of the Annals of Family Medicine.

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Cancer Treatment Lacking for HIV-Infected Patients

WEDNESDAY, May 18, 2016 (HealthDay News) -- While powerful HIV medications are allowing patients to live longer, these same patients are less likely to get treatment for cancer if it develops, according to a study published online May 17 in Cancer.

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Skeletal Muscle TRIB3 Mediates Diet-Induced Insulin Resistance

WEDNESDAY, May 18, 2016 (HealthDay News) -- Skeletal muscle TRIB3 mediates glucose-induced insulin resistance (GIIR) in a mouse model of diabetes, according to a study published online May 10 in Diabetes.

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Prophylactic High-Dose rhEPO No Benefit for Preemies

WEDNESDAY, May 18, 2016 (HealthDay News) -- Prophylactic early high-dose recombinant human erythropoietin (rhEPO) given intravenously to very preterm infants does not improve neurodevelopmental outcomes at 2 years corrected age, according to a study published in the May 17 issue of the Journal of the American Medical Association.

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For New Antipsychotic Users, Dose, Duration Impact Mortality

TUESDAY, May 17, 2016 (HealthDay News) -- Dose and duration of therapy are associated with mortality for new antipsychotic users, according to a study published online May 10 in the Journal of the American Geriatrics Society.

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Hospitalists Need Strategies for Providing Adequate Pain Relief

MONDAY, May 16, 2016 (HealthDay News) -- Hospitalists report limited success and satisfaction for management of acute exacerbations of chronic pain with opioids, according to a study published online May 9 in the Journal of Hospital Medicine.

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Specific Language Important in Heart Failure Communication

MONDAY, May 16, 2016 (HealthDay News) -- Specific language is important for patient experience and shared decision-making in heart failure, according to research published in the June 1 issue of The American Journal of Cardiology.

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Novel Index Predicts Survival After Chemo in Pancreatic Cancer

MONDAY, May 16, 2016 (HealthDay News) -- For patients with advanced pancreatic cancer receiving chemotherapy, the systemic inflammation response index (SIRI), based on peripheral neutrophil, monocyte, and lymphocyte counts, can predict survival, according to a study published online May 6 in Cancer.

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Complementary Medicine Use Up With Chronic Conditions

MONDAY, May 16, 2016 (HealthDay News) -- Adults with multiple chronic conditions frequently use complementary and alternative medicine (CAM), according to a study published online May 5 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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FDA Issues Stronger Warning on Side Effects of Fluoroquinolones

FRIDAY, May 13, 2016 (HealthDay News) -- Stronger warnings about the possible side effects of fluoroquinolones were issued Thursday by the U.S. Food and Drug Administration.

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CAM Use May Affect Breast Cancer Patients' Chemo Decisions

FRIDAY, May 13, 2016 (HealthDay News) -- Women with early-stage breast cancer who utilize complementary and alternative medicine (CAM) may delay recommended chemotherapy, according to research published online May 12 in JAMA Oncology.

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Fewer Self-Injury Events With Lithium for Bipolar Disorder

FRIDAY, May 13, 2016 (HealthDay News) -- Patients with bipolar disorder taking lithium have lower rates of self-harm and unintentional injury compared to those taking other mood stabilizers, according to research published online May 11 in JAMA Psychiatry.

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Fall Risk Up With Initiation, Intensification of HTN Meds

FRIDAY, May 13, 2016 (HealthDay News) -- For older adults, initiation and intensification of antihypertensive medication is associated with a short-term increased risk of serious fall injuries, according to a study published online May 10 in Circulation: Cardiovascular Quality and Outcomes.

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New Insight Might Aid Diagnosis, Treatment of Sjögren's Syndrome

THURSDAY, May 12, 2016 (HealthDay News) -- Rab3D and Rab27 proteins play an important role in the enhanced release of cathepsin S (CTSS) from lacrimal gland acinar cells (LGAC) in Sjögren's syndrome (SS), according to an experimental study published online April 13 in the American Journal of Physiology-Cell Physiology.

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Two Years of Tamoxifen Offers Long-Term Survival Benefit

THURSDAY, May 12, 2016 (HealthDay News) -- For premenopausal women with breast cancer, two years of tamoxifen is associated with long-term survival benefit, according to a study published online May 9 in the Journal of Clinical Oncology.

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DEA Weighing Change in Medical Marijuana Rules

WEDNESDAY, May 11, 2016 (HealthDay News) -- The U.S. Drug Enforcement Administration (DEA) is weighing whether to loosen its classification of marijuana, which would remove many restrictions on its use in medical research. If that occurs, doctors could start getting answers to the questions they regularly receive from patients regarding marijuana's clinical benefits.

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Metreleptin Ups Resting-State Connectivity in Lipodystrophy

WEDNESDAY, May 11, 2016 (HealthDay News) -- For patients with lipodystrophy (LD), resting-state connectivity is significantly increased in three brain areas with metreleptin treatment, with decreased hunger feelings and diminished incentive value of food, according to a study published online May 10 in Diabetes.

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Nilotinib Associated With Case of Scurvy

WEDNESDAY, May 11, 2016 (HealthDay News) -- Nilotinib is associated with scurvy, possibly because of its effects on cutaneous metabolism, according to a letter to the editor published online April 28 in the Journal of Cutaneous Pathology.

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Misoprostol Should Be Considered in Postpartum Hyperthermia

WEDNESDAY, May 11, 2016 (HealthDay News) -- The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia, rigors, and tachycardia, according to a case report published in the June issue of Obstetrics & Gynecology.

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Ketamine May Ease Suicidal Thoughts in Major Depression

WEDNESDAY, May 11, 2016 (HealthDay News) -- Low doses of ketamine may quickly reduce suicidal thoughts in patients with treatment-resistant depression, according to a study published online May 10 in the Journal of Clinical Psychiatry.

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Macitentan Doesn't Reduce Number of New Digital Ulcers

WEDNESDAY, May 11, 2016 (HealthDay News) -- The endothelin-1 blocker macitentan does not reduce the number of new digital ulcers over 16 weeks among patients with systemic sclerosis and active ischemic digital ulcers, according to a study published in the May 10 issue of the Journal of the American Medical Association.

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PPI Exposure Accelerates Aging in Lab Endothelial Cells

WEDNESDAY, May 11, 2016 (HealthDay News) -- Esomeprazole accelerates aging of endothelial cells in lab tests, raising red flags about its long-term effect on cardiovascular health, according to research published online May 10 in Circulation Research.

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CDC Updates Zika Testing Guidance for Urine Samples

TUESDAY, May 10, 2016 (HealthDay News) -- The interim diagnostic testing guidance for Zika virus in public health laboratories has been updated, according to a report published in the May 10 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Marijuana-Linked Fatal MVAs Up in WA State After Legalization

TUESDAY, May 10, 2016 (HealthDay News) -- The number of fatal motor vehicle crashes involving marijuana more than doubled after Washington state legalized the sale of the drug, according to a study from the AAA Foundation for Traffic Safety.

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Topical Bimatoprost Ocular Insert Reduces IOP

TUESDAY, May 10, 2016 (HealthDay News) -- Use of a topical bimatoprost ocular insert is associated with a clinically relevant reduction in mean intraocular pressure (IOP) over six months, according to a study published online May 5 in Ophthalmology.

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Drug Allergy Passport Advised for Patients With Hypersensitivity

TUESDAY, May 10, 2016 (HealthDay News) -- A drug allergy passport, providing information on culprit drugs, clinical manifestations, and alternate drugs to prescribe, should be provided to patients with drug hypersensitivity, according to a position paper published online May 4 in Allergy.

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Cutting Brand-Name Drug Use Could Save U.S. $73 Billion

TUESDAY, May 10, 2016 (HealthDay News) -- Americans could save tens of billions of dollars with more efficient drug use, replacing brand-name drugs with their generic equivalents whenever possible, according to a study published online May 9 in JAMA Internal Medicine.

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Survival for HCV Cirrhosis, SVR Same As General Population

TUESDAY, May 10, 2016 (HealthDay News) -- For patients with compensated hepatitis C virus (HCV) cirrhosis, those who achieve sustained virologic response (SVR) on an interferon-based (IFN) regimen have survival comparable to that of the general population, according to research published online April 5 in the Journal of Hepatology.

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Genetic Variants ID Treatment Response in Psoriasis

TUESDAY, May 10, 2016 (HealthDay News) -- Genetic variants have been identified in psoriasis patients that correlate with anti-tumor necrosis factor (TNF)-α treatment response, according to research published online April 30 in the Journal of Dermatology.

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Preadmission SSRI Use Ups Stroke Mortality in Diabetes

MONDAY, May 9, 2016 (HealthDay News) -- For patients with diabetes, preadmission selective serotonin reuptake inhibitor (SSRI) use is associated with increased risk of stroke mortality, according to a study published online May 3 in the Journal of Internal Medicine.

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Venlafaxine-Induced Rise in Intraocular Pressure Described

MONDAY, May 9, 2016 (HealthDay News) -- In a case report published online April 30 in Clinical & Experimental Ophthalmology, venlafaxine-induced increase in intraocular pressure (IOP) is described in a patient with open angle glaucoma.

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Regular Aspirin Use May Protect Against Bile Duct Cancer

MONDAY, May 9, 2016 (HealthDay News) -- Regular aspirin use may lower the risk of bile duct cancer, according to a study published online April 26 in Hepatology.

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Microbiome Linked to Infectious Complications in AML

MONDAY, May 9, 2016 (HealthDay News) -- For patients with acute myelogenous leukemia (AML) undergoing induction chemotherapy (IC), gastrointestinal microbiome composition is associated with infectious complications, according to a study published online May 3 in Cancer.

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United States Still Has Shortages of Acute, Non-Acute Drugs

FRIDAY, May 6, 2016 (HealthDay News) -- Drug shortages remain a problem in the United States despite government legislation meant to increase availability, according to a study published in the May issue of Health Affairs.

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Long-Term Treatment Benefit Seen in Relapse-Onset MS

FRIDAY, May 6, 2016 (HealthDay News) -- For patients with relapse-onset multiple sclerosis (MS), disease-modifying therapy protects against long-term disability accrual, according to a study published online May 4 in the Annals of Neurology.

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Analytics Approach Could Improve Chemo Combinations

FRIDAY, May 6, 2016 (HealthDay News) -- Models based on machine learning and optimization could improve chemotherapy regimens to be tested in phase III clinical trials without altering the toxicity outcomes, according to a study published in the May issue of Management Science.

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Cilostazol Doesn't Prevent Periprocedural MI in ACS

FRIDAY, May 6, 2016 (HealthDay News) -- For patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), adjunctive loading dose of cilostazol is not associated with prevention of periprocedural myocardial infarction (PMI), according to a study published online May 1 in Cardiovascular Therapeutics.

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New Rule Extends FDA Authority Over Tobacco, Nicotine Products

THURSDAY, May 5, 2016 (HealthDay News) -- The U.S. Food and Drug Administration said Thursday that it is banning the sale of electronic cigarettes to minors, as part of its long-awaited plan to extend the agency's regulatory powers across all tobacco products.

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Probiotic Supplements Beneficial in Rheumatoid Arthritis

THURSDAY, May 5, 2016 (HealthDay News) -- Probiotic supplementation seems beneficial for patients with rheumatoid arthritis (RA), according to a study published online May 2 in the International Journal of Rheumatic Diseases.

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Fluconazole Use May Raise Risk of Certain Birth Defects

THURSDAY, May 5, 2016 (HealthDay News) -- Prenatal use of low-dose fluconazole is associated with cleft lip with cleft palate and d-transposition of the great arteries, according to a study published in the May issue of the American Journal of Obstetrics & Gynecology.

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No Benefit Found for Perioperative Statin Therapy

THURSDAY, May 5, 2016 (HealthDay News) -- Taking statins right before cardiac surgery, once touted as a way to prevent common postoperative complications, has no benefit and may even cause harm, according to a study published in the May 5 issue of the New England Journal of Medicine.

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Ozanimod Shows Promise for Ulcerative Colitis Remission

WEDNESDAY, May 4, 2016 (HealthDay News) -- A daily dose of ozanimod (1 mg) shows potentially positive results for clinical remission of ulcerative colitis, compared to placebo, according to a preliminary study published in the May 5 issue of the New England Journal of Medicine.

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Laparoscopic Antireflux Sx May Provide Added Benefits in GERD

WEDNESDAY, May 4, 2016 (HealthDay News) -- Laparoscopic antireflux surgery (LARS) and esomeprazole are both beneficial for patients with chronic gastroesophageal reflux disease (GERD), but surgery may have an edge, according to research published in the May issue of Clinical Gastroenterology and Hepatology.

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Price Transparency Tool Doesn't Cut Health Care Spending

WEDNESDAY, May 4, 2016 (HealthDay News) -- Employee use of a price transparency tool does not cut health care spending, according to a study published in the May 3 issue of the Journal of the American Medical Association.

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Additional Treatments Offer Little Benefit for Pancreatic Cancer

WEDNESDAY, May 4, 2016 (HealthDay News) -- Additional treatments for locally advanced pancreatic cancer don't appear to improve survival, according to a study published in the May 3 issue of the Journal of the American Medical Association.

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CDC: Behavioral Therapy Recommended First for ADHD

WEDNESDAY, May 4, 2016 (HealthDay News) -- Behavior modification therapy is preferable to medication for treating children 2 to 5 years old who have attention-deficit/hyperactivity disorder (ADHD), U.S. health officials say.

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Flu Vaccine in Pregnancy Protects Mother and Infant

TUESDAY, May 3, 2016 (HealthDay News) -- Pregnant women who receive influenza vaccination may be protecting their infants as well as themselves against the virus, according to a new report published online May 3 in Pediatrics.

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Still Too Many Antibiotic Prescriptions Being Written

TUESDAY, May 3, 2016 (HealthDay News) -- Nearly one-third of the antibiotics prescribed in the United States aren't appropriate for the conditions being treated, according to research published in the May 3 issue of the Journal of the American Medical Association.

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Adding Antiviral to Sorafenib Is Cost-Effective in HCC

TUESDAY, May 3, 2016 (HealthDay News) -- The addition of antiviral therapy to sorafenib is a cost-effective option compared with sorafenib monotherapy in patients with advanced hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in China, according to a study published online April 27 in the Journal of Gastroenterology and Hepatology.

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Cognitive Behavioral Therapy Advised for Chronic Insomnia

TUESDAY, May 3, 2016 (HealthDay News) -- Cognitive behavioral therapy is recommended as the initial treatment for all adults with chronic insomnia disorder, according to a clinical practice guideline published online May 3 in the Annals of Internal Medicine.

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Artemisia Extract Ups Insulin Sensitivity in GDM

TUESDAY, May 3, 2016 (HealthDay News) -- For women with gestational diabetes mellitus, daily administration of Artemisia extract is associated with improved insulin sensitivity, according to a study published online April 27 in the Journal of Clinical Pharmacology.

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Report: Why Health Care Costs Are Lower in Europe Than U.S.

TUESDAY, May 3, 2016 (HealthDay News) -- European residents have access to the same health care services as U.S. residents but pay much less, and this is related to several specific factors, according to a report published by INDIGOMED on April 25.

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FDA: Brintellix Changing Name to Avoid Confusion With Brilinta

TUESDAY, May 3, 2016 (HealthDay News) -- Following a July 2015 Drug Safety Communication that warned about name confusion between Brintellix and Brilinta resulting in prescribing errors, the antidepressant Brintellix (vortioxetine) is changing its name to Trintellix, according to the U.S. Food and Drug Administration.

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Psychotherapy May Ease Chemo-Related Cognitive Dysfunction

MONDAY, May 2, 2016 (HealthDay News) -- Cognitive-behavioral therapy (CBT) might help cancer survivors manage the long-term cognitive dysfunction some experience after chemotherapy, according to research published online May 2 in Cancer.

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FDA Approves Nuplazid for Parkinson's Hallucinations

MONDAY, May 2, 2016 (HealthDay News) -- Nuplazid (pimavanserin) has been approved by the U.S. Food and Drug Administration to treat hallucinations and delusions associated with Parkinson's disease.

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2017 May Offer Fewer Choices for Affordable Care Act Enrollees

MONDAY, May 2, 2016 (HealthDay News) -- With the nation's largest health insurer exiting all but a few Affordable Care Act exchanges next year, some Americans may be left with fewer choices and some might see higher monthly premiums.

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Markers That Predict Omalizumab Response Identified

MONDAY, May 2, 2016 (HealthDay News) -- Baseline serum periostin levels and levels of serum free immunoglobulin E (IgE) during treatment follow-up may be useful in assessing response to omalizumab treatment for asthma, according to a study published online April 26 in Allergy.

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Patients Often Dissatisfied With Acne Care

MONDAY, May 2, 2016 (HealthDay News) -- Patients frequently report ineffective consultations in acne care, according to a study published online April 26 in the British Journal of Dermatology.

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Exenatide Reduces Liver Fat in Type 2 Diabetes With Obesity

MONDAY, May 2, 2016 (HealthDay News) -- For patients with obesity and type 2 diabetes, exenatide reduces epicardial adipose tissue (EAT) and liver fat content, according to a study published online April 23 in Diabetes, Obesity and Metabolism.

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Many Doctors Reluctant to Reveal Mental Health Issues

Perceived stigma, fear of career repercussions hinder treatment, study suggests

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