Maternal Overweight, Obesity May Increase Childhood Epilepsy

Share this content:
Maternal Overweight, Obesity May Increase Childhood Epilepsy
Maternal Overweight, Obesity May Increase Childhood Epilepsy

TUESDAY, April 4, 2017 (HealthDay News) -- The rates of childhood epilepsy increase with maternal overweight and obesity, according to a study published online April 3 in JAMA Neurology.

Neda Razaz, M.P.H., Ph.D., from the Karolinska University Hospital in Stockholm, and colleagues examined the correlation between early pregnancy body mass index (BMI) and the risk of childhood epilepsy in a population-based cohort study involving 1,441,551 live single births at 22 or more completed gestational weeks, with complete covariate information available.

The researchers found that 0.5 percent of the children were diagnosed with epilepsy (46.5 percent female). Among children aged 28 days to 16 years, the overall incidence of epilepsy was 6.79 per 10,000 child-years. The adjusted hazard ratios for epilepsy among offspring by maternal BMI categories compared with normal-weight mothers were 1.11 for overweight, 1.20 for obesity grade I, 1.30 for obesity grade II, and 1.82 for obesity grade III. Children with malformations of the nervous system, hypoxic ischemic encephalopathy, and neonatal convulsions had significantly increased rates of epilepsy (adjusted hazard ratios, 46.4, 23.6, and 33.5, respectively). The rates of epilepsy were significantly increased among children with neonatal hypoglycemia, respiratory distress syndrome, and neonatal jaundice (adjusted hazard ratios, 2.10, 2.43, and 1.47, respectively).

"Given that overweight and obesity are modifiable, prevention of obesity may be an important public health strategy to reduce the incidence of childhood epilepsy," the authors write.

Abstract/Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Osimertinib Tops Standard EGFR-TKI for EGFR NSCLC

Osimertinib Tops Standard EGFR-TKI for <i>EGFR</i>&#43; NSCLC

Significantly longer median progression-free survival for osimertinib in previously untreated NSCLC

Distinct Features for Drug Use-Related Endophthalmitis

Distinct Features for Drug Use-Related Endophthalmitis

Injection drug users have fewer comorbidities and more improvement in visual acuity after intervention

Dating Violence Victimization, Nonmedical Rx Med Use Linked

Dating Violence Victimization, Nonmedical Rx Med Use Linked

Nonmedical use of prescription drugs linked to dating violence for male, female high school students

is free, fast, and customized just for you!

Already a member?

Sign In Now »