Maternal Hyperglycemia Not Linked to Obesity in Offspring

This article originally appeared here.
Share this content:
Maternal Hyperglycemia Not Linked to Obesity in Offspring
Maternal Hyperglycemia Not Linked to Obesity in Offspring

MONDAY, June 29, 2015 (HealthDay News) -- Maternal hyperglycemia seems not to be a risk factor for obesity in offspring aged 5 to 7 years after adjustment for maternal body mass index (BMI), according to a study published online June 19 in Diabetes Care.

Parag K. Thaware, from the Royal Victoria Hospital in Belfast, U.K., and colleagues examined the correlation between hyperglycemia during pregnancy and anthropometry in 5- to 7-year-old offspring. Women underwent a 75-gram oral glucose tolerance test (OGTT) at about 28 weeks of gestation. Overall, 1,320 offspring underwent weight, height, and skinfold thickness measures at age 5 to 7 years.

The researchers found that there was no correlation for maternal fasting plasma glucose (FPG), one-hour plasma glucose, or two-hour plasma glucose with BMI Z score or offspring skinfold sum independent of maternal BMI at OGTT and offspring birth weight Z score. With the offspring BMI Z score expressed as ≥85th, ≥95th, or 99th percentile and the sum of skinfolds expressed as ≥90th percentile specific for sex, this lack of correlation with maternal glycemia persisted. Maternal BMI at OGTT accounted for the initially significant relation between FPG and all offspring adiposity measures.

"After adjustment for maternal BMI at the OGTT, higher maternal FPG concentration during pregnancy (short of diabetes) is no longer a risk factor for obesity, as reflected by BMI and the sum of skinfolds in offspring aged 5 to 7 years," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »