Lower Rate of Adverse Events With Outpatient Treatment of PE

Share this content:
Lower Rate of Adverse Events With Outpatient Treatment of PE
Lower Rate of Adverse Events With Outpatient Treatment of PE

MONDAY, Feb. 6, 2017 (HealthDay News) -- For patients with hemodynamically stable pulmonary embolism (PE), outpatient management is associated with a lower rate of adverse events, according to research published online Jan. 20 in the Journal of Thrombosis and Haemostasis.

Pierre-Marie Roy, M.D., Ph.D., from Université d'Angers in France, and colleagues conducted a retrospective cohort propensity score analysis to determine the net clinical benefit of hospitalization versus outpatient management of normotensive patients with acute PE. A total of 1,081 hemodynamically stable PE patients were included in the matched cohort: 576 were treated as inpatients and 505 as outpatients.

The researchers found that the 14-day rate of adverse events was 13.0 and 3.3 percent for inpatients and outpatients, respectively (adjusted odds ratio, 5.07). For inpatients and outpatients, the three-month adverse event rate was 21.7 and 6.9 percent, respectively (odds ratio, 4.90). The 14-day rate of adverse events was 16.5 and 4.5 percent in the high-risk subgroup for hospitalized patients and outpatients, respectively (odds ratio, 4.16).

"Outpatient treatment of hemodynamically stable PE patients seems associated with a lower rate of adverse events than hospitalization and, if confirmed, may be considered as first-line management in patients not requiring specific in-hospital care, regardless of their initial risk stratification, if proper outpatient care can be provided," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Approves New Parkinson's Add-On Drug Xadago

FDA Approves New Parkinson's Add-On Drug Xadago

To help prevent 'off' episodes among users of levodopa/carbidopa

Infant Mortality Down in United States From 2005 to 2014

Infant Mortality Down in United States From 2005 ...

Largest decreases seen for infants of Asian or Pacific Islander and non-Hispanic black women

Intensive Strategy Addresses Hypoxemia After Cardiac Surgery

Intensive Strategy Addresses Hypoxemia After Cardiac Surgery

Intensive alveolar recruitment strategy linked to less severe pulmonary complications after cardiac sx

is free, fast, and customized just for you!

Already a member?

Sign In Now »