Lower Infection Risk for Coiled Versus Noncoiled Leads

This article originally appeared here.
Share this content:
Lower Infection Risk for Coiled Versus Noncoiled Leads
Lower Infection Risk for Coiled Versus Noncoiled Leads

MONDAY, Oct. 3, 2016 (HealthDay News) -- Percutaneous leads used for neurostimulation of the peripheral nervous system have a much lower risk of infection with a coiled design compared to noncoiled leads, according to a review published online Sept. 27 in Pain Practice.

Brian M. Ilfeld, M.D., from University of California, San Diego, and colleagues conducted a literature review to identify clinical studies of percutaneous neurostimulation of the peripheral nervous system. Eligible studies had neurostimulation of more than two days, included explicit information on adverse events, and had a primary end point of the number of infections per 1,000 indwelling days.

The researchers identified 43 studies that included both coiled (21 studies) and noncoiled (25 studies) leads. Three studies evaluated both. The risk of infection with noncoiled leads was 25 times greater than with coiled leads (P = 0.006). For coiled leads the infection rate was 0.03 infections per 1,000 indwelling days, and for noncoiled leads the infection rate was 0.83 infections per 1,000 indwelling days (P = 0.006).

"With many therapeutic goals such as functional improvements and the relief of pain requiring multiple weeks of stimulation, these findings could have significant implications in the choice of a lead design and the potential for extending the use of percutaneous peripheral neurostimulation," the authors write.

Several authors disclosed financial ties to pharmaceutical and medical device companies, including SPR Therapeutics, which partially funded the study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

900 Steps Tied to Functional Decline in Hospitalized Seniors

<900 Steps Tied to Functional Decline in Hospitalized ...

Walking <900 steps/day linked to hospitalization-associated functional decline

Thromboprophylaxis Not Effective After Knee Arthroplasty, Casting

Thromboprophylaxis Not Effective After Knee Arthroplasty, Casting

Does not prevent venous thromboembolism after knee arthroplasty, casting of lower leg

ASH: Lower Rate of Sickle Cell Pain Crises With Crizanlizumab

ASH: Lower Rate of Sickle Cell Pain Crises ...

Lower rate of crises per year; longer median time to first, second crises with high-dose therapy

is free, fast, and customized just for you!

Already a member?

Sign In Now »