Low Rate of Recurrence Seen for Serious Reactions to Vaccines

Share this content:
Low Rate of Recurrence Seen for Serious Reactions to Vaccines
Low Rate of Recurrence Seen for Serious Reactions to Vaccines

TUESDAY, Aug. 29, 2017 (HealthDay News) -- Severe vaccine reactions recur rarely, if ever, when a child receives the same vaccine again, or one with similar ingredients, according to a review published online Aug. 28 in Pediatrics.

Investigators with the Canadian Immunization Research Network, who were led by Gaston De Serres, M.D., Ph.D., searched the medical literature for research on recurrent vaccine side effects. They found 29 studies done between 1982 and 2016; most focused on children. Several studies followed children and adults who'd had allergy symptoms after a vaccination -- ranging from rashes and eye symptoms to anaphylaxis.

The researchers found that, overall, 5 percent had another allergic response after being re-vaccinated. No patient had anaphylaxis again. A few studies focused on hypotonic hyporesponsive episodes (HHEs). The investigators found that of 398 children who'd developed HHEs after being vaccinated, only three -- or 0.8 percent -- had a repeat episode the next time they were immunized. Fevers recur more often, the authors said. One study, for instance, focused on babies and young children who'd developed a fever after getting the flu shot: Just over half (52 percent) had the same reaction the next time around.

"Based on the published literature, reimmunization appears to be safe for patients with mild to moderate AEFIs [adverse events following immunization]," the authors write. "However, the data are insufficient to draw firm conclusions regarding the safety of reimmunization after a severe AEFI. High-quality studies by researchers estimating the vaccine-specific risk of recurrence and predictors of recurrence for each AEFI are needed to inform evidence-based immunization practices in this population."

Abstract/Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease


Sign up for myCME e-newsletters


More in Home

24-Hour Primary Care Clinics Would Improve Continuity of Care

24-Hour Primary Care Clinics Would Improve Continuity of ...

Model involving multiple doctors working shifts in their own clinic offers many benefits

Repeat BP Reading Needed in Children With Initial High Result

Repeat BP Reading Needed in Children With Initial ...

Based on initial reading, more than half of children would have incorrect classification

Brochure Can Improve Opioid Disposal Rates After Surgery

Brochure Can Improve Opioid Disposal Rates After Surgery

Patients more likely to dispose of unused opioids after getting information and recommendations

is free, fast, and customized just for you!

Already a member?

Sign In Now »