Low-Fat, Higher-Complex Carb Diet Aids Gestational Diabetes

This article originally appeared here.
Share this content:
Low-Fat, Higher-Complex Carb Diet Aids Gestational Diabetes
Low-Fat, Higher-Complex Carb Diet Aids Gestational Diabetes

TUESDAY, Aug. 11, 2015 (HealthDay News) -- A higher-complex carbohydrate/lower-fat (CHOICE) diet significantly improves gestational diabetes mellitus (GDM)-associated markers compared to the conventionally recommended low-carbohydrate/higher-fat (LC/CONV) diet, according to a small study published online July 29 in Diabetes Care.

Teri L. Hernandez, Ph.D., R.N., from the University of Colorado in Aurora, and colleagues randomized 12 diet-controlled overweight/obese women with GDM (at 31 weeks) to an isocaloric LC/CONV (40 percent carbohydrate/45 percent fat/15 percent protein; six participants) or CHOICE (60 percent/25 percent/15 percent, respectively; six participants) diet. All meals were provided. Adipose tissue (AT) was assessed via biopsy at 37 weeks.

The researchers found that after approximately seven weeks, fasting glucose (P = 0.03) and free fatty acids (P = 0.06) decreased on CHOICE, whereas fasting glucose increased on LC/CONV (P = 0.03). On the CHOICE diet, insulin suppression of AT lipolysis was improved, compared with LC/CONV (56 versus 31 percent; P = 0.005), consistent with improved insulin resistance. AT expression of multiple proinflammatory genes was lower (P < 0.01) on the CHOICE diet, compared to LC/CONV. With CHOICE, infant adiposity trended lower also.

"A CHOICE diet may improve maternal IR and infant adiposity, challenging recommendations for a LC/CONV diet," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »