Low-Dose Isotretinoin Therapeutic for Seborrhea

Share this content:
Low-Dose Isotretinoin Therapeutic for Seborrhea
Low-Dose Isotretinoin Therapeutic for Seborrhea

MONDAY, Oct. 31, 2016 (HealthDay News) -- For patients with moderate-to-severe seborrhea and seborrheic dermatitis, low-dose oral isotretinoin can be therapeutic, according to a study published online Oct. 25 in the International Journal of Dermatology.

Cristhine de Souza Leão Kamamoto, M.D., Ph.D., from the Universidade Federal de São Paulo in Brazil, and colleagues determined the efficacy and safety of low-dose oral isotretinoin in the treatment of moderate-to-severe seborrhea and seborrheic dermatitis on the scalp and/or face. Over six months the trial was conducted in two groups: Patients in Group ISO received isotretinoin 10 mg every other day; patients in Group X received antiseborrheic topical treatment.

There were 45 patients with a mean age of 28.7 ± 5.8 years in Group ISO and 29.8 ± 6.5 years in Group X. The researchers observed a significant decrease in the rate of sebum production in Group ISO. In both groups, patient opinion, investigator, and quality of life assessments improved.

"Low-dose oral isotretinoin can be a therapeutic modality for moderate to severe seborrhea and seborrheic dermatitis," the authors write.

Germed Pharma donated the oral isotretinoin; L'Oréal Brasil and Galderma Brasil donated the topical products.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Illicit Marijuana Use Up in States With Legal Medical Use

Illicit Marijuana Use Up in States With Legal ...

Cannabis use disorder is also rising faster in states with legalization laws

Chromosome Instability Test Prognostic in NSCLC

Chromosome Instability Test Prognostic in NSCLC

Chromosome instability associated with higher risk of relapse, death within 2 years

CDC: Opioid-Related Mortality Rate Might Be Underestimated

CDC: Opioid-Related Mortality Rate Might Be Underestimated

Death certificates from drug-linked infections may not label opioids as possible cause

is free, fast, and customized just for you!

Already a member?

Sign In Now »