Long-Term Insulin Pump Use Reduces Mortality in T1DM

Share this content:
Long-Term Insulin Pump Use Reduces Mortality in T1DM
Long-Term Insulin Pump Use Reduces Mortality in T1DM

FRIDAY, Aug. 14, 2015 (HealthDay News) -- For individuals with type 1 diabetes, long-term use of continuous subcutaneous insulin infusion (insulin pump therapy) is associated with reduced cardiovascular and all-cause mortality, according to a study published online June 22 in The BMJ.

Isabelle Steineck, M.D., from the Aarhus University Hospital in Denmark, and colleagues examined the long-term effects of insulin pump therapy on cardiovascular diseases and mortality. Data were included for 18,168 people with type 1 diabetes, of whom 2,441 used insulin pump therapy and 15,727 used multiple daily insulin injections. Patients were followed for a mean of 6.8 years, with 114,135 person-years.

The researchers found that, compared with multiple daily injections, insulin pump therapy led to adjusted hazard ratios that were significantly lower for fatal coronary heart disease (0.55), fatal cardiovascular disease (coronary heart disease or stroke; 0.58), and all-cause mortality (0.73). For fatal or non-fatal coronary heart disease and fatal or non-fatal cardiovascular disease, hazard ratios were lower, but not significantly so. Per 1,000 person-years, the unadjusted differences were 3.0 events of fatal coronary heart disease, 3.3 events of fatal cardiovascular disease, and 5.7 events for all-cause mortality. The results of subgroup analyses were similar when lower body mass index and previous cardiovascular diseases were excluded.

"Among people with type 1 diabetes, use of insulin pump therapy is associated with lower cardiovascular mortality than treatment with multiple daily insulin injections," the authors write.

One author disclosed receiving lecture fees from Sanofi and Novo Nordisk

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Dietary changes, other meds, and even surgery can lower cardiovascular risk similarly to statins

Negative Effects Seen With Video Gaming 9 Hours/Week

Negative Effects Seen With Video Gaming 9+ Hours/Week

Benefits seen with one hour a week, but behavioral problems appear to rise at nine hours a week

Improved Adult Lung Function Linked to Childhood Farm Life

Improved Adult Lung Function Linked to Childhood Farm ...

First study to report beneficial effects of growing up on a farm on adult FEV1

is free, fast, and customized just for you!

Already a member?

Sign In Now »