Lidocaine, Hyaluronidase Mix Works Faster in Myofascial Pain

This article originally appeared here.
Share this content:
Lidocaine, Hyaluronidase Mix Works Faster in Myofascial Pain
Lidocaine, Hyaluronidase Mix Works Faster in Myofascial Pain

THURSDAY, Oct. 29, 2015 (HealthDay News) -- In patients with myofascial pain syndrome (MPS), trigger point injection (TPI) with lidocaine and hyaluronidase works more quickly on the first day following injection than lidocaine alone, but there are no significant differences between the methods after four days, according to a study published online Oct. 7 in Pain Practice.

Ji Won Choi, M.D., from the Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues randomized 61 adults (aged 25 to 75 years) with MPS affecting both trapezius muscles to treatment with either lidocaine (31 patients; 3.2 mL 0.5 percent) or hyaluronidase (30 patients; 3.2 mL 0.5 percent lidocaine + hyaluronidase 600 IU/mL). All patients received TPI. The verbal numerical rating scale (VNRS), the neck disability index (NDI), and the short form of brief pain inventory (BPI-SF) were used to evaluate outcomes.

The researchers found that in both groups, VNRS decreased on days four, seven, and 14, compared to pre-TPI. In the lidocaine + hyaluronidase group, there was also a decrease in VNRS on day one. However, there were no significant VNRS differences between the groups. Both groups experienced significant decreases in NDI and BPI-SF scores after TPI.

"TPI consisting of lidocaine mixed with hyaluronidase worked more effectively than lidocaine alone on post-TPI day one," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

CDC Concerned About Falling Flu Vaccination Rates

CDC Concerned About Falling Flu Vaccination Rates

Decline among vulnerable older adults is of particular concern

One in Five With Non-Valvular A-Fib Receiving Digoxin

One in Five With Non-Valvular A-Fib Receiving Digoxin

Indication for digoxin use was considered inappropriate in 59.8 percent in Turkish cohort

Rapid, Successful Response to ART for Many Patients With HIV

Rapid, Successful Response to ART for Many Patients ...

Factors associated with virological success include having undetectable viral load, use of three drugs

is free, fast, and customized just for you!

Already a member?

Sign In Now »