Laser Alone or With Peel Effective for Mixed Melasma

This article originally appeared here.
Share this content:
Laser Alone or With Peel Effective for Mixed Melasma
Laser Alone or With Peel Effective for Mixed Melasma

WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- Low-fluence Q-switched Nd-YAG laser alone or with modified Jessner's peel are equally effective regimens for mixed melasma hyperpigmentation, according to a study published online Oct. 22 in the Journal of Cosmetic Dermatology.

Fatma Saleh, M.D., from Minia University in Egypt, and colleagues compared the efficacy of Q-switched Nd-YAG laser alone or with modified Jessner's peel in mixed melasma in dark skin. Nineteen patients received six sessions of laser on the left side of the face and alternating laser and modified Jessner's on the right side. Clinical evaluation was performed through modified melasma area and severity index at one month after the last session. Histopathological, immunohistochemical, and computerized morphometric analysis were used for assessments.

The researchers found that there was significant clinical improvement on both sides of the face without a significant difference between the two sides. Ill-defined mottled hypopigmentation was observed in 21.05 percent of patients at the sixth laser session on the left side of the face. After two treatment modalities, histopathologically, melanin particle surface area and number of MART-1-positive cells (total, epidermal, and dermal) were significantly decreased without significant difference in the reduction percentage between both sides of the face.

"Combined method is preferred, especially in dark skin, for obtaining better cosmetic result with fewer side effects of multiple laser sessions and decreasing cost rate of laser," conclude the authors.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

High Costs Associated With Physician Burnout, Attrition

High Costs Associated With Physician Burnout, Attrition

Economic loss at Stanford over two years expected to range from $15.5 million to $55.5 million

Insulin Doesn't Prevent Diabetes in Relatives of T1DM Patients

Insulin Doesn't Prevent Diabetes in Relatives of T1DM ...

Oral insulin doesn't delay onset in autoantibody-positive relatives of patients with type 1 diabetes

Workplace Sexual Harassment Ongoing in Women, Up for Men

Workplace Sexual Harassment Ongoing in Women, Up for ...

Women report more adverse effects after SH than men, but SH can trigger depression, anxiety in men

is free, fast, and customized just for you!

Already a member?

Sign In Now »