Kidney Damage Seen in Most Patients With Long-Lasting T1D

This article originally appeared here.
Share this content:
Kidney Damage Seen in Most Patients With Long-Lasting T1D
Kidney Damage Seen in Most Patients With Long-Lasting T1D

MONDAY, Oct. 30, 2017 (HealthDay News) -- Most patients with type 1 diabetes (T1D) of long duration have some degree of kidney disease, according to a study published online Oct. 4 in Diabetes Care.

Tina Costacou, Ph.D., and Trevor J. Orchard, M.D., from the University of Pittsburgh examined the 50-year cumulative kidney complication risk in 932 participants from a childhood-onset T1D cohort diagnosed during 1950 to 1980. Overall, 144 participants died before baseline (1986 to 1988), 130 were followed with periodic surveys, and 658 were followed with biennial surveys.

The researchers found that end-stage renal disease (ESRD) affected 60 percent of the cohort by 50 years of T1D duration, while macroalbuminuria and microalbuminuria affected 72 and 88 percent, respectively. In recent cohorts there was little evidence for declines in cumulative incidence, except for ESRD, which had a 45 percent decrease by 40 years of T1D duration, while microalbuminuria increased 3 percent and macroalbuminuria did not change. The lowest risk was seen for onset before age 6 years, and there was usually no difference in incidence by sex.

"Some degree of kidney disease in T1D is virtually universal at long durations and not declining, which has major implications for health care and research strategies," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease


Sign up for myCME e-newsletters


More in Home

Automated Central System Offers Time Savings for Pharmacists

Automated Central System Offers Time Savings for Pharmacists

Cart-fill process using new automated system is more efficient, frees up time for other roles

Therapeutic Horseback Riding Can Help Alleviate PTSD in Veterans

Therapeutic Horseback Riding Can Help Alleviate PTSD in ...

Study found statistically and clinically significant reduction in PTSD scores after six weeks of THR

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Six-year antidiabetes treatment initiation rate also much lower after bariatric surgery

is free, fast, and customized just for you!

Already a member?

Sign In Now »