June 2015 Briefing - Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for June 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Three Issues to Consider Before Selecting EHR

TUESDAY, June 30, 2015 (HealthDay News) -- Work flow, features and functionality, and technical infrastructure should all be considered in advance of selecting an electronic heath record (EHR) system, according to an article published in Medical Economics.

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New Naloxone Capsule Safe for Opioid-Induced Constipation

TUESDAY, June 30, 2015 (HealthDay News) -- A new naloxone sustained release (NSR) capsule appears to be safe and efficacious for opioid-induced constipation (OIC), according to a study published online June 24 in Pain Medicine.

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Sequence of Shots May Lead to Effective HIV Vaccine

TUESDAY, June 30, 2015 (HealthDay News) -- A sequence of immunizations against HIV might hold the key to a successful vaccine, a new experimental study suggests. The study was published in the June 18 issue of Cell.

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Web Process to Provide Timely Guidance in HCV Management

TUESDAY, June 30, 2015 (HealthDay News) -- -- A living document has been developed to aid practitioners treating patients infected with hepatitis C virus (HCV). A document update and a summary of recommendations have been published online June 25 in Hepatology.

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Many Primary Care Physicians Misinformed About Opioids

MONDAY, June 29, 2015 (HealthDay News) -- Physicians who are ill-informed about opioids may be unintentionally contributing to their misuse, according to new research published online June 22 in the Clinical Journal of Pain.

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Statin Use Linked to Improved Post-Surgical Outcomes

MONDAY, June 29, 2015 (HealthDay News) -- Statin use might help reduce major complications after lung surgery, according to a study published in the June issue of the Journal of Thoracic and Cardiovascular Surgery.

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Indiana Lifts Ban on Needle Exchange to Curb HIV Outbreak

MONDAY, June 29, 2015 (HealthDay News) -- Allowing needle-exchange programs is one way to curtail the recent HIV outbreak in rural Indiana, according to a viewpoint piece published online June 24 in the New England Journal of Medicine.

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H3N2 Mutation to Blame for Low Efficacy of 2014-15 Flu Vaccine

MONDAY, June 29, 2015 (HealthDay News) -- A mutation in the H3N2 virus led to a mismatch between it and the H3N2 strain used to create the 2014-2015 vaccine, according to research published June 25 in Cell Reports.

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Methadone Linked to Initial QTc Prolongation in Chronic Pain

FRIDAY, June 26, 2015 (HealthDay News) -- For patients with chronic pain, methadone is associated with a small, but nonsignificant, initial increase in QTc, which does not persist, according to a study published in the June issue of Pain Medicine.

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SCOTUS Upholds Subsidies for Affordable Care Act

FRIDAY, June 26, 2015 (HealthDay News) -- The U.S. Supreme Court upheld on Thursday the legality of tax subsidies for millions of Americans who signed up for health insurance under the Affordable Care Act.

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Steroid Avoidance May Not Help Reduce Posttransplant Diabetes

FRIDAY, June 25, 2015 (HealthDay News) -- For kidney transplant recipients, steroid avoidance has limited impact for reducing new-onset diabetes after transplantation (NODAT), according to a study published in the July issue of the American Journal of Transplantation.

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Pharmacist-Managed Warfarin Therapy Beats Usual Care

THURSDAY, June 25, 2015 (HealthDay News) -- Pharmacist-managed warfarin therapy (PMWT) is superior to a usual medical care (UMC) model for management of warfarin therapy, according to a systematic review published online June 22 in the Journal of Clinical Pharmacology.

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'Smart Insulin Patch' Holds Promise for T1DM

THURSDAY, June 25, 2015 (HealthDay News) -- A microneedle-array patch ("smart insulin patch") containing glucose-responsive vesicles (GRVs), which are loaded with insulin and sensitive to hypoxia, can regulate blood glucose in a mouse model of type 1 diabetes. The findings were published online June 22 in the Proceedings of the National Academy of Sciences.

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Intradermal HBV Vaccine Efficient for Intramuscular Nonresponders

THURSDAY, June 25, 2015 (HealthDay News) -- For intramuscular hepatitis B virus (HBV) vaccine nonresponders, intradermal vaccine administration seems efficacious and safe, according to a study published online June 23 in the Journal of Gastroenterology and Hepatology.

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Lack of Consistent Supplement Use Documentation for Inpatients

THURSDAY, June 25, 2015 (HealthDay News) -- Upon hospital admission, most patients are not asked if they take dietary supplements, according to a study published recently in Patient Education and Counseling.

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Prenatal Exposure to H2 Blockers, PPIs Ups Asthma Risk

THURSDAY, June 25, 2015 (HealthDay News) -- Prenatal exposure to H2 blockers (H2Bs) or proton pump inhibitors (PPIs) is associated with a small but significantly increased risk of asthma in offspring, according to a study published online June 20 in the Journal of Clinical Pharmacology.

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Viagra, Other ED Meds Don't Raise Melanoma Risk

WEDNESDAY, June 24, 2015 (HealthDay News) -- A new review of data involving over 20,000 men does find a slightly higher risk of melanoma in men who took erectile dysfunction (ED) medications versus those who didn't; however, the increased risk is tied to lifestyle factors rather than the medications themselves. The findings were published in the June 23/30 issue of the Journal of the American Medical Association.

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Drug for Rheumatoid Arthritis May Also Help Ease Vitiligo

WEDNESDAY, June 24, 2015 (HealthDay News) -- Researchers report that a drug for rheumatoid arthritis may be a promising treatment for vitiligo. The findings were published online June 24 in JAMA Dermatology.

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Dermatologist Tutorial Helps Minimize Acne Rx Side Effects

WEDNESDAY, June 24, 2015 (HealthDay News) -- For Korean patients with acne, fixed-dose combination adapalene 0.1 percent and benzoyl peroxide 2.5 percent gel (A-BPO) is more efficacious than benzoyl peroxide (BPO), with similar skin irritation levels that can be improved with dermatologists' tutorials for A-BPO application, according to a study published online June 20 in the Journal of Dermatology.

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Edible Cannabis Products Often Mislabeled

WEDNESDAY, June 24, 2015 (HealthDay News) -- Most edible cannabis products sampled in three major U.S. cities are mislabeled, often containing more or less active ingredient than indicated on the packaging, according to a report published in the June 23/30 issue of the Journal of the American Medical Association.

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ACOG: Doctors Should Urge Against Prenatal Marijuana Use

TUESDAY, June 23, 2015 (HealthDay News) -- Doctors should discourage women from using marijuana during pregnancy and breastfeeding, due to the potential effects that the drug's active ingredients can have on a child's brain development, new guidance states. The committee opinion was released Monday by the American College of Obstetricians and Gynecologists (ACOG) and published in the July issue of Obstetrics & Gynecology.

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FDA Approves New Antiplatelet Drug for Patients Undergoing PCI

TUESDAY, June 23, 2015 (HealthDay News) -- Kengreal (cangrelor) has been approved by the U.S. Food and Drug Administration to prevent blood clots from forming during angioplasty.

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VA/DoD Release Guidelines for Dyslipidemia Management

TUESDAY, June 23, 2015 (HealthDay News) -- A joint clinical practice guideline for the management of dyslipidemia for cardiovascular disease risk reduction in adults has been summarized and published online June 22 in the Annals of Internal Medicine.

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Variability Identified in Bridging Practices Among Pharmacists

TUESDAY, June 23, 2015 (HealthDay News) -- Optimal management of subtherapeutic international normalized ratios (INRs) is unclear, with differences in bridging practices among pharmacists seen for levels of experience, residency training, and prescribing privileges. These findings were published online June 18 in the Journal of Clinical Pharmacy and Therapeutics.

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Acid Suppression Medications Up C. difficile Risk in Children

TUESDAY, June 23, 2015 (HealthDay News) -- Use of acid suppression medication is associated with increased risk of Clostridium difficile infection (CDI) in infants and children, according to a study published online June 9 in Clinical Infectious Diseases.

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Medical Identity Theft Incidents Increasing

MONDAY, June 22, 2015 (HealthDay News) -- Medical identity theft is on the rise, costly to consumers, and challenging to resolve, according to the fifth annual report published by the Ponemon Institute.

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Subclinical Hypothyroidism Ups DM Risk Only With Statin Use

MONDAY, June 22, 2015 (HealthDay News) -- Hypothyroidism is associated with increased risk of diabetes mellitus (DM); however, subclinical hypothyroidism appears to increase this risk only with statin use, according to research published online June 12 in Diabetes Care.

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Caution in Social Media Age: Self-Promotion Can Backfire

FRIDAY, June 19, 2015 (HealthDay News) -- In a series of experiments, researchers found that people who self-promote often offend others. The study was published in the June issue of Psychological Science.

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Nephrologists Actively Manage Meds After Kidney Transplant

FRIDAY, June 19, 2015 (HealthDay News) -- For adult kidney transplant recipients, nephrologists take an active approach to medication management, according to a study published online June 17 in the Journal of Evaluation in Clinical Practice.

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Osteoarthritis Care Not Lining Up With Recommendations

FRIDAY, June 19, 2015 (HealthDay News) -- The quality of osteoarthritis care is inadequate for all treatment domains, according to a meta-analysis published online June 17 in the Journal of Evaluation in Clinical Practice.

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Hundreds Arrested Nationwide for Medicare/Medicaid Fraud

FRIDAY, June 19, 2015 (HealthDay News) -- Hundreds of people have been charged after health care fraud sweeps were made across the United States, the federal government said Thursday.

Health Highlights: June 19, 2015

FDA Cracks Down on Online Sale of Illegal Medical Products

FRIDAY, June 19, 2015 (HealthDay News) -- The U.S. Food and Drug Administration, along with international partners, moved this week against more than 1,050 websites that sell potentially dangerous counterfeit medicines and medical devices, the agency said Thursday.

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CDC: Narcon Overdose-Reversal Kits Are Saving Addicts' Lives

FRIDAY, June 19, 2015 (HealthDay News) -- Friends and family members have saved the lives of tens of thousands of opioid users from overdoses by using emergency injection kits containing naloxone (Narcan), according to a new federal report. The findings were published in the June 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Medications Can Increase Risk of Heat-Related Illness

FRIDAY, June 19, 2015 (HealthDay News) -- Commonly used medications may increase the risk of dehydration and heat-related illness during hot weather, according to an article published online June 13 in the Journal of Clinical Pharmacy and Therapeutics.

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TNF Inhibitors May Not Modify Polyarticular JIA Disease Process

THURSDAY, June 18, 2015 (HealthDay News) -- For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis factor inhibitor (TNFi) therapy, according to a study published in the May issue of Arthritis Care & Research.

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Antibiotics May Be Enough for Some Appendicitis Patients

WEDNESDAY, June 17, 2015 (HealthDay News) -- Although surgical removal of the appendix has long been a standard treatment, new research suggests that almost three-quarters of people treated with antibiotics could be spared appendectomy. The findings were published in the June 16 issue of the Journal of the American Medical Association.

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Ixekizumab Shows Promise in Psoriasis Treatment

WEDNESDAY, June 17, 2015 (HealthDay News) -- Ixekizumab, a humanized monoclonal antibody against the proinflammatory cytokine interleukin 17A, may offer a new and efficacious option for patients with moderate-to-severe psoriasis, according to two phase 3 clinical trials reported online June 10 in The Lancet.

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Direct Messaging Not Yet Widely Adopted by Physicians

TUESDAY, June 16, 2015 (HealthDay News) -- Direct secure messaging (Direct), which is a standardized protocol for exchanging clinical messages and attachments, has not been widely adopted by physicians, despite its potential for improving care coordination, according to an article published in Medical Economics.

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GI Antispasmodic, Anticholinergic Rx Use May Raise Injury Risk

TUESDAY, June 16, 2015 (HealthDay News) -- Gastrointestinal (GI) antispasmodic and anticholinergic medication use is associated with increased risk of injury in older adults, according to a study published online June 11 in the Journal of the American Geriatrics Society.

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ADHD Rx Studied for Cognitive Boost in Menopause

TUESDAY, June 16, 2015 (HealthDay News) -- Lisdexamfetamine (Vyvanse), a stimulant usually prescribed to children and adults with attention-deficit/hyperactivity disorder (ADHD), may help to improve menopausal women's executive function, a new, small study suggests. The findings were published online June 11 in Psychopharmacology.

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Review Examines Inappropriate Prescribing of IV Fluids

TUESDAY, June 16, 2015 (HealthDay News) -- Inappropriate prescribing of intravenous (IV) fluids most often involves incorrect volumes and types of IV fluids prescribed, according to a review published online June 11 in the Journal of Clinical Pharmacy and Therapeutics.

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Testosterone + Fenofibrate Yields Strongest Effect on Cardio Risks

TUESDAY, June 16, 2015 (HealthDay News) -- A combination of testosterone and fenofibrate may offer men with high cholesterol and late-onset hypogonadism the most cardiometabolic benefit, according to a study published online May 29 in Cardiovascular Therapeutics.

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Asthma Rx Deemed Less Likely to Work in Patients Aged 30 and Up

MONDAY, June 15, 2015 (HealthDay News) -- Asthma treatments, especially inhaled corticosteroids, are less likely to work for older patients, according to a study published online June 11 in the American Journal of Respiratory and Critical Care Medicine.

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Women Get Year's Worth of Birth Control Under New Oregon Law

MONDAY, June 15, 2015 (HealthDay News) -- A first-of-a-kind insurance law that allows women to obtain a year's worth of birth control at a time will take effect in Oregon on Jan. 1.

Health Highlights: June 12, 2015

DMARDs May Be Underused for Low Back Pain

MONDAY, June 15, 2015 (HealthDay News) -- Disease-modifying antirheumatic drugs (DMARDs) may be underutilized for treatment of low back pain (LBP), according to a review published online June 1 in Pain Practice.

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Low-Salt Diet Boosts Efficacy of Antihypertensives

MONDAY, June 15, 2015 (HealthDay News) -- A low-salt diet further improves the efficacy of antihypertensive drug regimens, according to a study published May 29 in the Journal of Clinical Pharmacology.

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Use of Novel Oral Anticoagulants Increasing in A-Fib

MONDAY, June 15, 2015 (HealthDay News) -- For patients with atrial fibrillation hospitalized with stroke or transient ischemic attack, use of novel oral anticoagulants (NOACs) has increased over time, according to a study published online June 9 in Circulation: Cardiovascular Quality and Outcomes.

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Younger Adults Receiving Excess Anticoagulant Dosing in PCI

FRIDAY, June 12, 2015 (HealthDay News) -- Many younger adults with acute myocardial infarction undergoing percutaneous coronary intervention (PCI) receive excess dosing of anticoagulants, with evidence of a trend toward an association between excess dosing and increased bleeding, according to a study published in the July 1 issue of The American Journal of Cardiology.

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Macrolide Resistance Doesn't Impact Pneumonia Outcomes

FRIDAY, June 12, 2015 (HealthDay News) -- Patients hospitalized with macrolide-resistant Streptococcus pneumoniae pneumonia are not more severely ill and do not have worse outcomes, according to a study published in the June 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Car Crash Risk Up for New Users of Sedating Sleep Meds

FRIDAY, June 12, 2015 (HealthDay News) -- Sedating sleep medications increase the risk for car accidents among new users compared with nonusers, with risk continued for up to a year among regular users, according to a new report published online June 11 in the American Journal of Public Health.

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Shorter Antibiotic Course Post Abdominal Surgery May Be Viable

THURSDAY, June 11, 2015 (HealthDay News) -- A shorter course of antibiotic treatment for abdominal infections after surgery may be as equally effective as a longer course, a new study suggests. The findings were published in the May 21 issue of the New England Journal of Medicine.

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FDA Panel Recommends Approval of Second PCSK9 Inhibitor

THURSDAY, June 11, 2015 (HealthDay News) -- On Wednesday, U.S. health officials recommended the approval of a second new PCSK9 inhibitor, evolocumab (Repatha).

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Venous Thromboembolism Rates Low After Colorectal Surgery

THURSDAY, June 11, 2015 (HealthDay News) -- For patients undergoing colorectal surgery, venous thromboembolism (VTE) rates are generally low, according to a study published online June 10 in JAMA Surgery.

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Duloxetine Appears Beneficial for Osteoarthritis Knee Pain

THURSDAY, June 11, 2015 (HealthDay News) -- Duloxetine significantly improves osteoarthritis knee (OAK) pain, according to a meta-analysis published online June 5 in Pain Medicine.

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Proton Pump Inhibitors Linked to Increased Risk of MI

WEDNESDAY, June 10, 2015 (HealthDay News) -- For U.S. adults with gastroesophageal reflux disease (GERD), the risk of myocardial infarction (MI) is slightly elevated among those using proton pump inhibitors, according to a review published online June 10 in PLOS ONE.

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Report Offers Guidance on Medical Ethics Education

WEDNESDAY, June 10, 2015 (HealthDay News) -- An analysis of the current state of medical ethics education in the United States has been published in the June issue of Academic Medicine. The article, the Romanell Report, also offers guidance to assist medial ethics educators in meeting expectations.

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Greater Decline in Renal Function With Warfarin in A-Fib

WEDNESDAY, June 10, 2015 (HealthDay News) -- For patients with atrial fibrillation, decline in renal function is significantly greater with warfarin versus dabigatran etexilate (DE), according to a study published in the June 16 issue of the Journal of the American College of Cardiology.

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One Vaccine Dose May Adequately Protect Against HPV

WEDNESDAY, June 10, 2015 (HealthDay News) -- One dose of the human papillomavirus (HPV) vaccine Cervarix could prevent as many cases of cervical cancer as the current two- and three-dose schedules, a new study contends. The findings were published online June 9 in The Lancet Oncology.

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FDA Panel Recommends Approval for PCSK9 Inhibitor

WEDNESDAY, June 10, 2015 (HealthDay News) -- U.S. health experts voted on Tuesday to recommend approval of the first of two drugs in a new class of cholesterol medications that reduce low-density lipoprotein (LDL) cholesterol in patients who don't fare well on statins. The related research was published online April 28 in the Annals of Internal Medicine.

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CDC: Drug-Resistant Foodborne Bacteria on Rise

WEDNESDAY, June 10, 2015 (HealthDay News) -- Antibiotic-resistant infections from foodborne germs still cause about 440,000 illnesses in the United States each year, the U.S. Centers for Disease Control and Prevention reported Tuesday.

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Rotavirus Vaccination Reduces Gastroenteritis Hospitalizations

TUESDAY, June 9, 2015 (HealthDay News) -- The widespread use of rotavirus vaccine has been very successful in the United States, according to a study published in the June 9 issue of the Journal of the American Medical Association.

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Ketorolac Doesn't Reduce Pain With IUD Placement

TUESDAY, June 9, 2015 (HealthDay News) -- For patients undergoing intrauterine device (IUD) placement, ketorolac does not reduce pain with placement, but is associated with pain reduction at five and 15 minutes after placement, according to a study published online June 5 in Obstetrics & Gynecology.

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Review Explores Effect of Sulfonylureas on Lipids in T2DM

TUESDAY, June 9, 2015 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), sulfonylureas seem to increase levels of free fatty acids (FFA) and triglycerides (TG) and lower low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), according to a meta-analysis published online June 4 in the Journal of Evidence-Based Medicine.

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Analysis Targets U.S. Hospitals With Highest Markups

TUESDAY, June 9, 2015 (HealthDay News) -- The 50 U.S. hospitals with the highest charge-to-cost ratio have markups approximately 10 times the Medicare-allowable costs, and most of these hospitals are for profit, according to a study published in the June issue of Health Affairs.

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Anticoagulation Appears Safe for Patients With Brain Mets

WEDNESDAY, June 3, 2015 (HealthDay News) -- Therapeutic anticoagulation is safe for treating venous thromboembolism in patients with cancer that has metastasized to the brain, according to new research. The study was published online May 18 in Blood.

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Larazotide Acetate 0.5 mg Found Beneficial in Celiac Disease

MONDAY, June 8, 2015 (HealthDay News) -- Larazotide acetate 0.5 mg is associated with improvement in symptoms of celiac disease (CeD), according to a study published in the June issue of Gastroenterology.

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Pain Care Providers at High Risk for Violence

MONDAY, June 8, 2015 (HealthDay News) -- Chronic pain care providers (CPCPs) are high risk targets for violence, according to research published online June 2 in Pain Medicine.

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CDC: Vaccine Production for 2015-16 Flu Season Underway

MONDAY, June 8, 2015 (HealthDay News) -- Having acknowledged that the 2014-15 flu vaccine was mismatched to the circulating influenza strains, U.S. health officials have strengthened next season's vaccine for broader protection.

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CDC Guidelines Update Treatment, Management of STDs

MONDAY, June 8, 2015 (HealthDay News) -- New recommendations have been provided to update the 2010 guidelines on the treatment and management of sexually transmitted diseases (STDs). The 2015 guidelines are available online in the June 5 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Misuse of Stimulants May Begin Earlier Than Expected

MONDAY, June 8, 2015 (HealthDay News) -- Misuse of prescription stimulant medications such as Ritalin and Adderall may begin at an earlier age than previously believed, according to research published in the July 1 issue of Drug and Alcohol Dependence.

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Majority of Fibromyalgia Drug Trials Are Industry Sponsored

FRIDAY, June 5, 2015 (HealthDay News) -- Most fibromyalgia drug therapy randomized controlled trials (FM-RCTs) are funded by industry, and many authors have financial conflicts of interest (FCOIs), according to a study published online May 27 in the International Journal of Rheumatic Diseases.

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Review: Short vs. Long Duration Dual Antiplatelet Tx After Stent

FRIDAY, June 5, 2015 (HealthDay News) -- Dual antiplatelet therapy (DAPT) continued beyond six months after drug-eluting stent implantation is associated with reduced stent thrombosis and myocardial infarction but also increased bleeding and all-cause mortality as compared to shorter-term DAPT therapy, according to a review published online May 25 in Cardiovascular Therapeutics.

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Gastritis Linked to Metformin-Related GI Side Effects in T2DM

FRIDAY, June 5, 2015 (HealthDay News) -- For patients with type 2 diabetes, asymptomatic gastritis is associated with metformin-related gastrointestinal side effects, according to a study published online May 29 in the Journal of Clinical Pharmacy and Therapeutics.

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FDA Panel Votes 18-6 to Approve Rx for Female Libido

FRIDAY, June 5, 2015 (HealthDay News) -- An advisory panel to the U.S. Food and Drug Administration recommended approval Thursday of flibanserin, a medication designed to treat hypoactive sexual desire disorder in premenopausal women.

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Statin + Ezetimibe May Benefit After Acute Coronary Syndrome

THURSDAY, June 4, 2015 (HealthDay News) -- In treatment following acute coronary syndrome, ezetimibe added to statin therapy appears beneficial, according to a study published online June 3 in the New England Journal of Medicine.

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Vaccine Tied to Less Postherpetic Neuralgia in Shingles

THURSDAY, June 4, 2015 (HealthDay News) -- Even when herpes zoster vaccination does not prevent the disease, it reduces the risk of postherpetic neuralgia (PHN), according to a new study published June 1 in the Journal of Infectious Diseases.

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Withholding ARBs After Surgery Linked to Higher Mortality

THURSDAY, June 4, 2015 (HealthDay News) -- For veterans regularly prescribed angiotensin receptor blockers (ARBs) admitted for noncardiac surgery, failure to resume ARB therapy by postoperative day two is associated with increased mortality risk, according to a study published online May 30 in Anesthesiology.

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Metabolic Syndrome Up With ADT in Prostate Cancer

THURSDAY, June 4, 2015 (HealthDay News) -- For patients with prostate cancer treated with androgen deprivation therapy there are increases in components of metabolic syndrome and in the prevalence of full metabolic syndrome, according to a study published in the June issue of The Journal of Urology.

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NASH-Linked Changes Impact Metformin Pharmacokinetics

THURSDAY, June 4, 2015 (HealthDay News) -- Nonalcoholic steatohepatitis (NASH)-associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics, according to an experimental study published online May 27 in Diabetes Care.

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Most Part D Plans Cover at Least One Biologic DMARD

WEDNESDAY, June 3, 2015 (HealthDay News) -- Although most Medicare Part D plans cover at least one biologic disease-modifying antirheumatic drug (DMARD), copayments are high, according to a study published in the June issue of Arthritis & Rheumatology.

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Omega-3s May Be Useful Adjunct to Opioids in Pain Therapy

WEDNESDAY, June 3, 2015 (HealthDay News) -- Chronic omega-3 fatty acid (O3) supplementation has an additive effect when combined with acute dosages of morphine in an animal model, according to a study published online May 25 in the Journal of Pharmacy and Pharmacology.

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Some Varenicline Concerns Not Supported by Evidence

WEDNESDAY, June 3, 2015 (HealthDay News) -- Varenicline (Chantix) doesn't increase the risk of suicidal behavior, mental illness, criminal acts, or traffic accidents, according to a study published June 2 in The BMJ.

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Menopausal Symptoms Unaffected by Vitamin D, Calcium

WEDNESDAY, June 3, 2015 (HealthDay News) -- Vitamin D and calcium supplements do not help ease the symptoms of menopause, according to study results published online June 1 in Maturitas.

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Risk to Infant From SSRI Use in Late Pregnancy Deemed Small

TUESDAY, June 2, 2015 (HealthDay News) -- Infants born to mothers taking antidepressants in late pregnancy may be slightly more likely to develop persistent pulmonary hypertension of the newborn (PPHN), a new study suggests, but the risk is very small. The findings were published in the June 2 issue of the Journal of the American Medical Association.

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Review: Monitor Weight for Youth on Antipsychotics

TUESDAY, June 2, 2015 (HealthDay News) -- Youth prescribed antipsychotic medication should be monitored for exaggerated weight gain, and agents other than olanzapine, clozapine, and risperidone may be best in patients where obesity is a pre-existing concern, according to a review published online May 28 in Obesity Reviews.

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Women With HTN, Diabetes Less Likely to Use Alternative Rx

TUESDAY, June 2, 2015 (HealthDay News) -- Women with hypertension and diabetes are less likely to consult with a complementary and alternative medicine (CAM) practitioner and to self-prescribe CAM, according to a study published in the June 15 issue of The American Journal of Cardiology.

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Physician Intervention Doesn't Cut Maternal Vaccine Hesitancy

MONDAY, June 1, 2015 (HealthDay News) -- A physician-targeted communication intervention does not reduce maternal vaccine hesitancy, and schools with high levels of personal belief exemptions (PBEs) are often colocated with schools with elevated personal medical exemption (PME) rates, according to two studies published online June 1 in Pediatrics.

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