January 2017 Briefing - Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for January 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Review: Cardiopulmonary Event Rate Not Up With Propofol Use

TUESDAY, Jan. 31, 2017 (HealthDay News) -- The risk of cardiopulmonary adverse events is similar for propofol sedation and traditional sedation agents for gastrointestinal endoscopic procedures, according to a review published in the February issue of Clinical Gastroenterology and Hepatology.

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Diabetes Mellitus Prevalence Higher in HIV-Infected Adults

TUESDAY, Jan. 31, 2017 (HealthDay News) -- HIV-infected adults have diabetes mellitus (DM) prevalence of 10.3 percent, which is higher than general population adults, according to a study published in the January issue of BMJ Open Diabetes Research & Care.

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Guidelines Developed for Use of Growth Hormone in Children

TUESDAY, Jan. 31, 2017 (HealthDay News) -- Use of growth hormone (GH) in children and adolescents should be considered carefully, with assessment of the risks and benefits necessary for each patient, according to guidelines published in the January issue of Hormone Research in Paediatrics.

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Azithromycin Given in Labor Cuts Maternal, Neonatal Infections

TUESDAY, Jan. 31, 2017 (HealthDay News) -- Administration of azithromycin during labor is associated with a reduction in maternal and neonatal clinical infections, according to a study published online Jan. 27 in Pediatrics.

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Insulin Glargine 300 U/mL Beats Glargine 100 U/mL in T1DM

TUESDAY, Jan. 31, 2017 (HealthDay News) -- For patients with type 1 diabetes, receipt of insulin glargine 300 U/mL (Gla-300) is associated with better glucose control than glargine 100 U/mL (Gla-100), regardless of injection time, according to a study published online Jan. 23 in Diabetes Care.

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Very Low LDL-C Levels Well Tolerated With Alirocumab

MONDAY, Jan. 30, 2017 (HealthDay News) -- For patients treated with alirocumab, very low low-density lipoprotein cholesterol (LDL-C) levels are not associated with increased treatment-emergent adverse event rates, according to research published in the Feb. 7 issue of the Journal of the American College of Cardiology.

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Hypoglycemia Induces Pro-Inflammatory Functional Changes

MONDAY, Jan. 30, 2017 (HealthDay News) -- Hypoglycemia can promote mobilization of specific subsets of leukocytes and induce pro-inflammatory functional changes in immune cells, according to a study published online Jan. 23 in Diabetes.

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Economic Benefit for Combo Statin/TG-Specific Tx in T2DM

FRIDAY, Jan. 27, 2017 (HealthDay News) -- For patients with type 2 diabetes mellitus, there is a substantial economic benefit to treatment with statin-triglyceride (TG)-specific combination lipid therapy compared with monotherapy or no lipid pharmacotherapy, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

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HT to Preserve Fertility Doesn't Appreciably Affect Survival

FRIDAY, Jan. 27, 2017 (HealthDay News) -- For young patients with endometrial cancer, survival does not appear to be significantly impacted by hormone therapy (HT) before surgery to preserve fertility, according to a study published online Dec. 27 in Cancer.

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Ketone Monitoring Infrequent in Patients With Type 1 Diabetes

FRIDAY, Jan. 27, 2017 (HealthDay News) -- For patients with type 1 diabetes (T1D), self-reported ketone monitoring is infrequent overall, according to research published online Jan. 18 in Diabetes Care.

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Aromatase Inhibitor + Growth Hormone Can Optimize Height

FRIDAY, Jan. 27, 2017 (HealthDay News) -- Use of an aromatase inhibitor in combination with growth hormone seems effective for optimizing height in 11β-hydroxylase-deficient congenital adrenal hyperplasia (CAH), according to a case report published online Jan. 26 in Pediatrics.

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Unusual Amnestic Syndrome Seen With Opioid Abuse

FRIDAY, Jan. 27, 2017 (HealthDay News) -- Short-term memory loss may be yet another price of America's opioid addiction epidemic, according to a report published in the Jan. 27 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Nephrologists Often Don't Treat Depression in Dialysis Patients

FRIDAY, Jan. 27, 2017 (HealthDay News) -- Depression is common among kidney failure patients undergoing dialysis, but efforts to get them on antidepressants often fail, according to research published online Jan. 26 in the Clinical Journal of the American Society of Nephrology.

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U.S. Children Make Over 6 Million Office Visits/Year for ADHD

FRIDAY, Jan. 27, 2017 (HealthDay News) -- An average 6.1 million physician visits in 2012 to 2013 were made by children aged 4 to 17 with a primary diagnosis of attention-deficit/hyperactivity disorder (ADHD), according to a January data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Antibiotics, Not Poor Hygiene, Main Cause of C. difficile Outbreak

FRIDAY, Jan. 27, 2017 (HealthDay News) -- Reducing the use of fluoroquinolones has curbed an outbreak of Clostridium difficile that began in 2006 in England, according to a study published online Jan. 24 in The Lancet Infectious Diseases.

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Study Questions Tx of Subclinical Hypothyroidism in Pregnancy

THURSDAY, Jan. 26, 2017 (HealthDay News) -- Treatment of subclinical hypothyroidism in pregnancy may not always be the best option, according to a study published online Jan. 25 in The BMJ.

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Universal CAR T-Cell Therapy Helped Treat ALL in Two Infants

THURSDAY, Jan. 26, 2017 (HealthDay News) -- Two infants with B-cell acute lymphoblastic leukemia (ALL) are in remission after treatment with genetically modified immune system cells, according to a report on the two cases published in the Jan. 25 issue of Science Translational Medicine.

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Bezlotoxumab Promising Against Recurrent Clostridium difficile

THURSDAY, Jan. 26, 2017 (HealthDay News) -- Bezlotoxumab (Zinplava) is effective in reducing the risk of recurrent Clostridium difficile infection, according to research published in the Jan. 26 issue of the New England Journal of Medicine.

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Verapamil Benefits Chronic Rhinosinusitis With Nasal Polyps

THURSDAY, Jan. 26, 2017 (HealthDay News) -- For patients with chronic rhinosinusitis with nasal polyps (CRSwNP), the first-generation inhibitor of epithelial P-glycoprotein (P-gp; an efflux pump that is overexpressed in CRSwNP), verapamil hydrochloride (HCl), is associated with improvement in outcome measures, according to a letter to the editor study published online Jan. 23 in the Journal of Allergy and Clinical Immunology.

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Most PCPs Oppose Complete Repeal of the Affordable Care Act

THURSDAY, Jan. 26, 2017 (HealthDay News) -- A majority of primary care doctors oppose full repeal of the Affordable Care Act, according to a perspective piece published online Jan. 25 in the New England Journal of Medicine.

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Study Assesses Sublingual Fentanyl Vs Morphine for CA Pain

THURSDAY, Jan. 26, 2017 (HealthDay News) -- For patients with severe cancer pain episodes, fentanyl sublingual tablets (FST) offer analgesia with modest to moderate increased risk of lower efficacy compared with subcutaneous morphine (SCM), according to a study published online Jan. 23 in the Journal of Clinical Oncology.

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Chemo May Be Overused in Younger Patients With Colon CA

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- Young and middle-aged colon cancer patients may be getting chemotherapy more often than is warranted, according to a study published online Jan. 25 in JAMA Surgery.

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Climbazole Ups Retinoid-Linked Biological Activities

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- Climbazole enhances retinoid-associated biological activities in vivo and in vitro, according to a study published online Jan. 19 in the International Journal of Cosmetic Science.

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Meta-Analysis: Caprini Score IDs Benefit of VTE Prophylaxis

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- Perioperative venous thromboembolism (VTE) prophylaxis is beneficial only for surgical patients with Caprini scores of ≥7, according to a meta-analysis published online Jan. 23 in the Annals of Surgery.

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Continuous Glucose Monitoring Ups Control in T1DM Patients

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- A continuous glucose monitor (CGM) helps patients with type 1 diabetes better manage their blood glucose levels, according to two studies published in the Jan. 24/31 issue of the Journal of the American Medical Association.

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Diabetes Requiring Insulin Tied to Increased Stroke Risk in A-Fib

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- For patients with atrial fibrillation (AF), diabetes requiring insulin, but not diabetes without insulin treatment, is associated with an increased risk of stroke/systemic embolism, according to a study published in the Jan. 31 issue of the Journal of the American College of Cardiology.

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Safety Profile of Red Yeast Rice Found Similar to Statins

TUESDAY, Jan. 24, 2017 (HealthDay News) -- The cholesterol-lowering supplement red yeast rice could pose the same health risks to users as statin drugs, according to a study published online Jan. 19 in the British Journal of Clinical Pharmacology.

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Severe Side Effects Common Among Breast Cancer Patients

TUESDAY, Jan. 24, 2017 (HealthDay News) -- About half of early-stage breast cancer patients experience severe side effects from their treatment, according to a study published online Jan. 24 in Cancer.

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Diabetes Care Compromised for Hispanics With Limited English

TUESDAY, Jan. 24, 2017 (HealthDay News) -- Hispanic-American type 2 diabetes patients who lack proficiency in English are much less likely than non-Hispanic patients to take newly prescribed diabetes medications as directed, according to a study published online Jan. 23 in JAMA Internal Medicine.

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Extending Rx Exclusivity Could Boost Study for Rare Diseases

MONDAY, Jan. 23, 2017 (HealthDay News) -- Extending the market exclusivity for existing drugs that are granted subsequent U.S. Food and Drug Administration (FDA) approval for a new rare disease indication would provide manufacturers with substantial compensation, often in excess of the cost of conducting the trials, according to research published in the January issue of Health Affairs.

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Exenatide, Pioglitazone Effective for Poorly Controlled T2DM

MONDAY, Jan. 23, 2017 (HealthDay News) -- For patients with long-standing poorly controlled type 2 diabetes mellitus (T2DM) on metformin plus a sulfonylurea, combination therapy with exenatide and pioglitazone is effective and safe, according to a study published online Jan. 17 in Diabetes Care.

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Androgen Suppression Tx May Prevent Intravesical Recurrence

FRIDAY, Jan. 20, 2017 (HealthDay News) -- For men with bladder cancer, androgen suppression therapy may be prophylactic for intravesical recurrence, according to a study published in the February issue of The Journal of Urology.

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FDA Approves Trulance for Chronic Idiopathic Constipation

FRIDAY, Jan. 20, 2017 (HealthDay News) -- Trulance (plecanatide) has been approved by the U.S. Food and Drug Administration to treat persistent idiopathic constipation in adults.

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Early Study Results Promising for Genital Herpes Vaccine

FRIDAY, Jan. 20, 2017 (HealthDay News) -- A new vaccine for herpes simplex virus type 2 could be nearing human clinical trials, according to research published online Jan. 19 in PLOS Pathogens.

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High SPF Sunscreen Offers Better Protection Than Beach Umbrella

FRIDAY, Jan. 20, 2017 (HealthDay News) -- Sunscreen with a high sun protection factor offers better protection than a standard beach umbrella, although neither completely prevents sunburn, according to a study published online Jan. 19 in JAMA Dermatology.

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Iatrogenic Cushing's Syndrome Described in 9-Year-Old Girl

FRIDAY, Jan. 20, 2017 (HealthDay News) -- In a case report published online Jan. 19 in Pediatrics, iatrogenic Cushing's syndrome (CS) is described in a 9-year-old girl who received topical ocular glucocorticoid (GC) treatment for bilateral iridocyclitis.

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Effectiveness of One-Dose MenACWY-D Drops Over Time

THURSDAY, Jan. 19, 2017 (HealthDay News) -- For adolescents, the effectiveness of the one-dose meningococcal (groups A, C, W, and Y) polysaccharide diphtheria toxoid conjugate vaccine (MenACWY-D) decreases at three to less than eight years post-vaccination, according to a study published online Jan. 18 in Pediatrics.

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Experimental Drug May Simplify Macular Degeneration Treatment

THURSDAY, Jan. 19, 2017 (HealthDay News) -- An experimental drug, AXT107, may one day make treatment simpler for patients with age-related macular degeneration, according to research published in the Jan. 18 issue of Science Translational Medicine.

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Oxytocin Ups Feeding, Social Skills in Infants With Prader-Willi

WEDNESDAY, Jan. 18, 2017 (HealthDay News) -- For infants with Prader-Willi syndrome (PWS), oxytocin (OXT) administration is associated with improvement in feeding and social skills, according to a study published online Jan. 18 in Pediatrics.

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Number of Infants Born to Women Using Opioids Up Sharply

WEDNESDAY, Jan. 18, 2017 (HealthDay News) -- Over a decade, there was a nearly five-fold increase in the number of infants born each year to American women who used opioids during the pregnancy, according to a new report prepared for the U.S. Congress by the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA). There was also a dramatic rise in the number of infants born with a dependency on opioids.

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Hypertension Onset After Age 80 May Protect Against Dementia

WEDNESDAY, Jan. 18, 2017 (HealthDay News) -- Developing hypertension in very old age may provide some protection from dementia, according to a study published online Jan. 17 in Alzheimer's & Dementia.

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Physician Excess Charges Create Financial Burden for Patients

TUESDAY, Jan. 17, 2017 (HealthDay News) -- Many doctors bill their private-paying patients two, three, even six times more than what Medicare pays for the same services, according to a research letter published in the Jan. 17 issue of the Journal of the American Medical Association.

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Antiplatelets Cut Preterm Birth in Those at Risk for Preeclampsia

TUESDAY, Jan. 17, 2017 (HealthDay News) -- Among women at risk for preeclampsia, antiplatelet agents reduce the risk of spontaneous preterm birth at less than 37 and less than 34 weeks of gestation, according to a meta-analysis published in the February issue of Obstetrics & Gynecology.

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Interaction Between Antibiotics, Obesity Is Complex

TUESDAY, Jan. 17, 2017 (HealthDay News) -- The interaction between antibiotics and human growth and obesity is explored in a historical perspective piece published in the Jan. 17 issue of the Annals of Internal Medicine.

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Glyburide, Metformin Have Similar Effect in Gestational DM

TUESDAY, Jan. 17, 2017 (HealthDay News) -- For patients with gestational diabetes mellitus (GDM), glyburide and metformin are comparable in terms of glucose control and safety, according to a study published online Jan. 11 in Diabetes Care.

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Lower Inpatient Costs for Dabigatran, Rivaroxaban in A-Fib

TUESDAY, Jan. 17, 2017 (HealthDay News) -- For patients with newly diagnosed atrial fibrillation (AF), inpatient costs are lower with dabigatran and rivaroxaban than with warfarin, according to a letter published online in the Jan. 24 issue of the Journal of the American College of Cardiology.

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Patient Perception of Provider Concern Impacts Satisfaction

MONDAY, Jan. 16, 2017 (HealthDay News) -- For patients with chronic pain receiving opioids, provider satisfaction is not associated with functional outcomes; however, patient perception of provider concern impacts perceived satisfaction, according to a study published online Jan. 13 in Pain Practice.

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Addition of Cetuximab to CRT Cuts Locoregional Failure in Anal CA

MONDAY, Jan. 16, 2017 (HealthDay News) -- Addition of cetuximab to chemoradiation (CRT) is associated with a reduction in locoregional failure (LRF) rates in squamous cell carcinoma of the anal canal (SCCAC), according to a study published online Jan. 9 in the Journal of Clinical Oncology.

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Pace of Influenza Activity Picking Up Across the United States

FRIDAY, Jan. 13, 2017 (HealthDay News) -- The pace of flu activity continues to quicken across the United States, and probably hasn't peaked yet, according to an assessment by the U.S. Centers for Disease Control and Prevention.

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Fecal Transplant No Better Than Oral Antibiotic for C. difficile

FRIDAY, Jan. 13, 2017 (HealthDay News) -- A single fecal transplant delivered by enema is apparently no more effective than oral antibiotics in treating recurring cases of Clostridium difficile infection, according to research published recently in Clinical Infectious Diseases.

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Modest Links for Systemic Medication Use, IOP in Glaucoma

FRIDAY, Jan. 13, 2017 (HealthDay News) -- Some systemic medication has a modest effect on intraocular pressure (IOP) among Asian patients with glaucoma, according to research published online Jan. 12 in JAMA Ophthalmology.

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Cognitive Stress Reduces Levodopa Effect in Parkinson's

FRIDAY, Jan. 13, 2017 (HealthDay News) -- Cognitive co-activation is associated with a significantly smaller levodopa effect on resting tremor in Parkinson's disease (PD), according to a study published online Jan. 10 in CNS Neuroscience & Therapeutics.

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177Lu-Dotatate Ups PFS in Midgut Neuroendocrine Tumors

THURSDAY, Jan. 12, 2017 (HealthDay News) -- For patients with advanced midgut neuroendocrine tumors, lutetium-177 (177Lu)-Dotatate is associated with longer progression-free survival than high-dose octreotide long-acting repeatable (LAR), according to a study published in the Jan. 12 issue of the New England Journal of Medicine.

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Tetracycline + Colchicine Effective in Hidradenitis Suppurativa

THURSDAY, Jan. 12, 2017 (HealthDay News) -- Tetracycline combined with colchicine is effective for treatment of hidradenitis suppurativa (HS), according to a study published online Jan. 4 in the International Journal of Dermatology.

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β-Blockers Linked to Reduced Mortality in HFrEF, A-Fib

THURSDAY, Jan. 12, 2017 (HealthDay News) -- β-blockers are associated with significantly reduced mortality, but not hospitalizations, in patients with heart failure and reduced ejection fraction (HFrEF) and atrial fibrillation (AF), according to a study published online Jan. 11 in JACC: Heart Failure.

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Sitagliptin Has Neutral CV Risk Effect in Elderly With T2DM, CVD

THURSDAY, Jan. 12, 2017 (HealthDay News) -- Sitagliptin has a neutral effect on cardiovascular risk among older patients with type 2 diabetes, according to a study published online Jan. 5 in Diabetes Care.

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Worsening QoL Linked to Early Tx Discontinuation in Breast Cancer

THURSDAY, Jan. 12, 2017 (HealthDay News) -- For women with breast cancer, experiencing a worsening in menopause-specific quality of life (QoL) is associated with early treatment discontinuation, according to a study published online Jan. 9 in the Journal of Clinical Oncology.

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Achieving LDL-Particle Targets Deemed Cost-Effective

WEDNESDAY, Jan. 11, 2017 (HealthDay News) -- Achieving targets of low-density lipoprotein (LDL), as measured by LDL particle number (LDL-P) compared with LDL-cholesterol (LDL-C), is cost-effective, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

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Excessive FDA Regulation Driving High Drug Prices

WEDNESDAY, Jan. 11, 2017 (HealthDay News) -- The excessive regulatory regime at the U.S. Food and Drug Administration is an important driver of high drug prices, and should be curbed to introduce more competition and lower prices, according to a report published online Jan. 5 by the National Center for Policy Analysis.

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Many Families Find High Health Care Deductibles Burdensome

WEDNESDAY, Jan. 11, 2017 (HealthDay News) -- High-deductible health plans have multiplied in recent years, and they may pose a significant financial burden on Americans with chronic conditions, according to two studies published online Jan. 9 in JAMA Internal Medicine.

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USPSTF Reaffirms Endorsement of Prenatal Folic Acid Supplements

TUESDAY, Jan. 10, 2017 (HealthDay News) -- In a recommendation statement published in the Jan. 10 issue of the Journal of the American Medical Association, the U.S. Preventive Services Task Force (USPSTF) reaffirms that folic acid supplements reduce the risk of neural tube defects.

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Acid Suppression in Pregnancy Linked to Childhood Asthma

TUESDAY, Jan. 10, 2017 (HealthDay News) -- Women who take acid-suppressing medications during pregnancy may have a child at increased risk of developing asthma, according to a review published online Jan. 9 in the Journal of Allergy and Clinical Immunology.

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Dual Antiplatelet Tx Similar to Aspirin Post-CABG in Diabetes

TUESDAY, Jan. 10, 2017 (HealthDay News) -- For post-coronary artery bypass grafting (CABG) patients with diabetes, cardiovascular and bleeding outcomes do not differ significantly with use of dual antiplatelet therapy (DAPT) versus aspirin, according to a study published in the Jan. 17 issue of the Journal of the American College of Cardiology.

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Mathematical Model Can Simulate HbA1c Progression in T2DM

TUESDAY, Jan. 10, 2017 (HealthDay News) -- A mathematical model (MM) can simulate hemoglobin A1c (HbA1c) trajectories in type 2 diabetes mellitus (T2DM) models, according to a study published online Dec. 27 in Diabetes, Obesity and Metabolism.

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Many Ischemic Stroke Survivors Not Prescribed Anticoagulants

TUESDAY, Jan. 10, 2017 (HealthDay News) -- Many patients surviving ischemic stroke are not discharged with an oral anticoagulant (OAC), according to a study published online Dec. 30 in the Journal of the American Geriatrics Society.

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Valerian Root Supplement Use Linked to Severe Hyponatremia

MONDAY, Jan. 9, 2017 (HealthDay News) -- A case of acute severe hyponatremia secondary to polydipsia in association with increased use of herbal remedies has been presented in BMJ Case Reports.

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Panic Disorder May Up Odds of Depression Rx Side Effects

MONDAY, Jan. 9, 2017 (HealthDay News) -- For patients with chronic depression, comorbid panic disorder is associated with increased likelihood of side effects during treatment, according to a study published online Jan. 3 in the Journal of Clinical Psychiatry.

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Ivermectin Has Topical Anti-Inflammatory Properties

MONDAY, Jan. 9, 2017 (HealthDay News) -- Ivermectin (IVM) has anti-inflammatory properties that could be beneficial in treatment of T-cell mediated skin inflammatory diseases, according to an experimental study published online Jan. 4 in Allergy.

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Delayed Chemo After Surgery Still Beneficial in Lung Cancer

FRIDAY, Jan. 6, 2017 (HealthDay News) -- Chemotherapy that's been delayed due to slow recovery from non-small-cell lung cancer (NSCLC) surgical resection can still provide real benefit to patients, according to a study published online Jan. 5 in JAMA Oncology.

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Sorafenib Effect on HCC Survival Depends on Hepatitis Status

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For patients with advanced unresectable hepatocellular carcinoma, the effect of sorafenib on overall survival (OS) is dependent on patients' hepatitis status, according to a meta-analysis published online Jan. 3 in the Journal of Clinical Oncology.

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Data on Effectiveness of Morning Sickness Drug May Be Flawed

FRIDAY, Jan. 6, 2017 (HealthDay News) -- Pyridoxine-doxylamine (Diclectin), used to manage the nausea and vomiting associated with morning sickness, may not be as effective as once believed, according to a new analysis published online Jan. 4 in PLOS One.

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Fibromyalgia Symptoms Improve With CoQ10 Supplementation

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For patients with fibromyalgia (FM), coenzyme Q10 (CoQ10) supplementation is associated with improvement in clinical symptoms, according to a letter to the editor published online Jan. 4 in CNS Neuroscience & Therapeutics.

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Acid Suppression Rx Linked to Risk of C. difficile, Campylobacter

FRIDAY, Jan. 6, 2017 (HealthDay News) -- Proton pump inhibitor (PPI) and H2 receptor antagonist (H2RA) users may be at higher risk of infection with Clostridium difficile and Campylobacter bacteria, according to a study published online Jan. 5 in the British Journal of Clinical Pharmacology.

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Continuing Warfarin Protective After Diagnosis of Dementia

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For veterans receiving warfarin for nonvalvular atrial fibrillation, continuing warfarin after a diagnosis of dementia is associated with a protective effect in prevention of stroke and mortality, according to a study published online Dec. 30 in the Journal of the American Geriatrics Society.

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Chemo Benefits Patients After Nephroureterectomy in UTUC

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For patients undergoing radical nephroureterectomy (RNU) for pT3/T4 and/or pN+ upper tract urothelial carcinoma (UTUC), adjuvant chemotherapy (AC) use is associated with an overall survival benefit, according to a study published online Jan. 3 in the Journal of Clinical Oncology.

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Meta-Analysis Links Omega-3 Fatty Acid Consumption to T2DM

THURSDAY, Jan. 5, 2017 (HealthDay News) -- Consumption of single omega-3 is associated with an increased risk of type 2 diabetes (T2D), with dosage, ethnicity, trial duration, and recruited age influencing the effect, according to a meta-analysis published online Dec. 29 in the Journal of Diabetes Investigation.

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2000 to 2011 Saw Shift in Treatment for Advanced NSCLC

THURSDAY, Jan. 5, 2017 (HealthDay News) -- From 2000 to 2011 there were shifts in the treatment of advanced-stage non-small-cell lung cancer (NSCLC), with modest survival gains, according to a study published online Jan. 3 in the Journal of Clinical Oncology.

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Letrozole Tops Aspirin for Halting Ovarian Hyperstimulation

THURSDAY, Jan. 5, 2017 (HealthDay News) -- For high-risk women, letrozole is more effective than aspirin for decreasing the incidence of moderate and severe early-onset ovarian hyperstimulation syndrome, according to a study published in the January issue of the American Journal of Obstetrics & Gynecology.

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Too Few U.S. Young Adults Being Prescribed Needed Statins

WEDNESDAY, Jan. 4, 2017 (HealthDay News) -- Too few American young adults are receiving needed statin medications, according to findings published online Jan. 4 in JAMA Cardiology.

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Fenofibrate May Reduce CVD in Patients With DM, Dyslipidemia

WEDNESDAY, Jan. 4, 2017 (HealthDay News) -- Fenofibrate therapy may reduce cardiovascular disease (CVD) in statin-treated patients with diabetes and dyslipidemia, according to a study published online Dec. 28 in JAMA Cardiology.

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Non-Liver-Related Critical Events Down With SVR in HCV+Cirrhosis

WEDNESDAY, Jan. 4, 2017 (HealthDay News) -- For patients with hepatitis C virus (HCV) infection and biopsy-proven cirrhosis, sustained viral response (SVR) is associated with a reduction in critical events, both liver and non-liver related, according to research published in the January issue of Gastroenterology.

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Metformin Tied to Better Clinical Outcomes in CKD, CHF, CLD

WEDNESDAY, Jan. 4, 2017 (HealthDay News) -- For patients with chronic kidney disease (CKD), congestive heart failure (CHF), or chronic liver disease (CLD) with hepatic impairment, metformin use is associated with improvements in clinical outcomes, according to a review published online Jan. 3 in the Annals of Internal Medicine.

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Sequential Empagliflozin, Linagliptin Diabetes Tx Effective

WEDNESDAY, Jan. 4, 2017 (HealthDay News) -- After metformin failure, sequential treatment escalation with empagliflozin and linagliptin is an effective diabetes treatment option due to additive effects on postprandial glucose control, according to a study published online Dec. 23 in Diabetes, Obesity and Metabolism.

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Zoledronic Acid Every 12 Weeks Noninferior in Bone Metastases

TUESDAY, Jan. 3, 2017 (HealthDay News) -- Use of zoledronic acid every 12 weeks does not result in increased risk of skeletal events compared with use every four weeks among patients with bone metastases due to breast cancer, prostate cancer, or multiple myeloma, according to a study published in the Jan. 3 issue of the Journal of the American Medical Association.

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ACP Updates Recommendations for Oral Medications in T2DM

TUESDAY, Jan. 3, 2017 (HealthDay News) -- The American College of Physicians (ACP) has updated recommendations on the oral pharmacologic treatment of type 2 diabetes in adults. The clinical practice guideline update was published online Jan. 3 in the Annals of Internal Medicine.

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Retailers Often Recommend Age-Restricted Supplements to Teens

TUESDAY, Jan. 3, 2016 (HealthDay News) -- Health food store employees frequently recommend creatine and testosterone boosters to under-age, male high school athletes, according to a study published online Jan. 2 in Pediatrics.

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More Cognitive Difficulties for Patients After Chemotherapy

TUESDAY, Jan. 3, 2016 (HealthDay News) -- Compared with non-cancer controls, patients with breast cancer treated with chemotherapy have more cognitive difficulties up to six months after treatment, according to a study published online Dec. 28 in the Journal of Clinical Oncology.

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Plasma Catecholamines Predict Post-Op A-Fib After Cardiac Sx

Plasma Catecholamines Predict Post-Op A-Fib After Cardiac Sx

Composite preoperative catecholamine marker linked to four-fold increased occurrence of POAF

Race, Sex Impact Risk of ESRD for Living Kidney Donors

Race, Sex Impact Risk of ESRD for Living ...

Increased risk of ESRD with black race and male sex; older age tied to increased risk in nonblack donors

Algorithm Integrated Into App Forecasts Glucose Levels

Algorithm Integrated Into App Forecasts Glucose Levels

Method using Gaussian process models produces personalized, nutrition-based forecast

is free, fast, and customized just for you!

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