January 2016 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for January 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Demand for Medical Office Space High and Increasing

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Demand for medical office space for ambulatory care is at a high point and looks likely to continue increasing, according to an article published in Forbes.

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Soy Foods May Blunt Reproductive Harm From BPA

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Soy intake may modify the association between bisphenol A (BPA) and fertility in women undergoing assisted reproduction, according to research published online Jan. 27 in the Journal of Clinical Endocrinology & Metabolism.

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Earlier Age at Menarche Linked to Increased Risk of GDM

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Earlier age at menarche is associated with increased risk of gestational diabetes mellitus (GDM), according to a study published online Jan. 26 in Diabetes Care.

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AMA Highlights Top Four Issues to Promote in State Legislation

THURSDAY, Jan. 28, 2016 (HealthDay News) -- The top four issues that will be promoted in state legislation in 2016 were discussed at the 2016 American Medical Association (AMA) State Legislative Strategy Conference, according to a report published by the AMA.

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New Approach Described for Type 1 Diabetes

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Alginate derivatives have been generated that can overcome the challenge of foreign body response in the use of implanted medical devices, and these materials show promise in diabetes, according to two studies published online Jan. 25 in Nature Biotechnology and Nature Medicine.

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Flavonol Intake May Contribute to Weight Maintenance

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Increased consumption of most flavonoid subclasses is inversely associated with weight change over time, according to a study published online Jan. 28 in The BMJ.

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Vitamin D Treatment Has No Effect in Prediabetes

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- For patients with prediabetes or diet-treated type 2 diabetes, high-dose vitamin D treatment has no effect on β-cell function, insulin sensitivity, or glycemic control, according to a study published online Jan. 19 in Diabetes Care.

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~1% of Physicians Account for One-Third of Malpractice Claims

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- A small number of physicians account for a considerable proportion of all paid malpractice claims, according to a study published in the Jan. 28 issue of the New England Journal of Medicine.

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Alternative Payment Models Can Help Improve Patient Care

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Alternative payment models (APMs) have been and are being developed that can allow physicians to offer new and improved services to their patients, according to a report published by the American Medical Association (AMA).

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Possibility for Health Care Legislation Changes in 2016

TUESDAY, Jan. 26, 2016 (HealthDay News) -- Given the current political climate and issues of bipartisan concern, 2016 could see certain changes to health care legislation, according to a report published in Medical Economics.

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Pulse Pressure Linked to Multiple Adverse Cardiovascular Outcomes

TUESDAY, Jan. 26, 2016 (HealthDay News) -- Pulse pressure (PP) is associated with multiple adverse cardiovascular outcomes, according to a study published in the Feb. 2 issue of the Journal of the American College of Cardiology.

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Overweight, Obesity Linked to Risk of Sudden Cardiac Death

TUESDAY, Jan. 26, 2016 (HealthDay News) -- Overweight and obese individuals are at increased risk of sudden cardiac death (SCD) and non-SCD, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

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At Least Three Factors Influence Timing of Dialysis Initiation

MONDAY, Jan. 25, 2016 (HealthDay News) -- The initiation of maintenance dialysis reflects an interplay between the care practices of physicians, sources of momentum for initiation, and physician-patient interactions, according to a study published online Jan. 25 in JAMA Internal Medicine.

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Hypoglycemia, Atherosclerosis Progression Link Explored

MONDAY, Jan. 25, 2016 (HealthDay News) -- In the Veterans Affairs Diabetes Trial, hypoglycemia was associated with coronary artery calcium (CAC) progression only in the standard therapy group (versus intensive therapy), according to research published online Jan. 19 in Diabetes Care.

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Estrogen Metabolism May Have an Impact on Stroke Recovery

MONDAY, Jan. 25, 2016 (HealthDay News) -- 2-methoxyestradiol (2-ME), an endogenous metabolite of estradiol, inhibits proliferation, pro-inflammatory responses, and phagocytosis in microglia, according to a study published online Jan. 5 in the American Journal of Physiology-Endocrinology and Metabolism.

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Considerable Symptom Burden With Adjuvant Endocrine Tx

MONDAY, Jan. 25, 2016 (HealthDay News) -- Patients treated with adjuvant endocrine therapy (ET) for primary breast cancer have considerable symptom burden, according to a study published online Jan. 19 in the Journal of Clinical Oncology.

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Patient Satisfaction With Doctors May Be on the Rise

FRIDAY, Jan. 22, 2016 (HealthDay News) -- More Americans than ever are satisfied with their visits to the doctor, according to a new survey conducted by The Harris Poll in September.

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Glucose Levels Linked to Cardiac Surgery Outcomes

FRIDAY, Jan. 22, 2016 (HealthDay News) -- For patients undergoing cardiac surgery, hyperglycemia is associated with worse outcomes for patients without diabetes, but with better outcomes for patients with insulin-treated diabetes, according to a study published online Jan. 19 in Diabetes Care.

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Review Shows Lasting Weight Loss for Very-Low-Energy Diets

THURSDAY, Jan. 21, 2016 (HealthDay News) -- Very-low-energy diets (VLEDs) seem to be beneficial for long-term weight loss, according to a review published online Jan. 18 in Obesity Reviews.

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Mutations in TUBB8 Linked to Form of Female Infertility

THURSDAY, Jan. 21, 2016 (HealthDay News) -- For a small number of women with a rare form of infertility, mutations in a particular gene may be the cause, according to a study published in the Jan. 21 issue of the New England Journal of Medicine.

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Antipsychotic-Exposed Youths Have Increased T2DM Risk

WEDNESDAY, Jan. 20, 2016 (HealthDay News) -- Youths treated with antipsychotics have increased cumulative risk and exposure-adjusted incidence of type 2 diabetes mellitus (T2DM), according to research published online Jan. 20 in JAMA Psychiatry.

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Less Hypoglycemia With Weight-Based Insulin in Hyperkalemia

WEDNESDAY, Jan. 20, 2016 (HealthDay News) -- Weight-based insulin dosing is associated with less hypoglycemia than standard dosing for patients with acute hyperkalemia weighing less than 95 kg, according to a study published online Jan. 13 in the Journal of Hospital Medicine.

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Guidelines Provided for Correct Way to Dismiss Patients

TUESDAY, Jan. 19, 2016 (HealthDay News) -- As insurers place increasing emphasis on evaluating physicians based on quality measures, management of noncompliant patients is becoming more complex, and can lead to patient dismissal, according to an article published in Medical Economics.

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Physicians Choose Less Aggressive Care at End of Life

TUESDAY, Jan. 19, 2016 (HealthDay News) -- Physicians facing death are less likely to demand aggressive care, according to two research letters published in the Jan. 19 issue of the Journal of the American Medical Association, a theme issue on death, dying, and end of life.

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B12 Deficiency Common in Long-Term Care Residents

TUESDAY, Jan. 19, 2016 (HealthDay News) -- Vitamin B12 deficiency is common among seniors in long-term care, according to a study published online Jan. 19 in the Applied Physiology, Nutrition, and Metabolism.

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Catch-Up Sleep May Reverse T2DM Risk Tied to Sleep Loss

TUESDAY, Jan. 19, 2016 (HealthDay News) -- Catch-up sleep may reverse the negative short-term impact of sleep loss on diabetes risk, at least in otherwise healthy fit young men, according to research published online Jan. 18 in Diabetes Care.

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Impact of T2DM Meds on Heart Failure Hospitalization Explored

TUESDAY, Jan. 19, 2016 (HealthDay News) -- For patients with type 2 diabetes, there is no association between hospitalization for heart failure and treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) versus sulfonylureas (SUs) or treatment with saxagliptin versus sitagliptin, according to a study published online Jan. 6 in Diabetes Care.

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Greater Transparency Being Promoted in Research

MONDAY, Jan. 18, 2016 (HealthDay News) -- Greater transparency is being promoted in clinical research, according to a health policy brief published online Jan. 14 in Health Affairs.

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Guidelines Presented for Primary Adrenal Insufficiency

MONDAY, Jan. 18, 2016 (HealthDay News) -- Recommendations have been developed to address the diagnosis and treatment of primary adrenal insufficiency. The new clinical practical guidelines were published online Jan. 13 in the Journal of Clinical Endocrinology & Metabolism.

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Ranolazine Added to Glimepiride Cuts HbA1c in T2DM

MONDAY, Jan. 18, 2016 (HealthDay News) -- For patients with type 2 diabetes on background glimepiride therapy, but not metformin, addition of ranolazine is associated with a significant reduction in hemoglobin A1c (HbA1c), according to research published online Jan. 8 in Diabetes, Obesity and Metabolism.

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Design of Physician Satisfaction Surveys Affects Results

MONDAY, Jan. 18, 2016 (HealthDay News) -- Patient satisfaction scores are influenced by the design and implementation of patient surveys, according to an article published in the January-February issue of Family Practice Management.

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Nonverbal Cues May Reveal a Physician's Racial Bias

FRIDAY, Jan. 15, 2016 (HealthDay News) -- A physician's body language may reveal racial bias against seriously ill black patients, according to research published in the January issue of the Journal of Pain and Symptom Management.

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Diabetes Mellitus Is Independent Risk Factor for A-Fib

FRIDAY, Jan. 15, 2016 (HealthDay News) -- Within a general population from China, diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF), with the correlation persisting after adjustment for cardiovascular risk factors, according to a study published online Jan. 8 in the Journal of Diabetes Investigation.

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Low Resilience to Stress in Teens May Up Later T2DM Risk

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Teens who have trouble coping with stress may be at increased risk for type 2 diabetes as adults, according to research published online Jan. 13 in Diabetologia.

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Sugar Warning Labels Might Help Parents Skip Soda for Children

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Health warning labels on sugar-sweetened beverages -- similar to those on cigarette packs -- might make parents less likely to buy such beverages for their children, according to research published online Jan. 14 in Pediatrics.

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Lower Live Birth Rate With Minimal Stimulation IVF

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Minimal stimulation in vitro fertilization (mini-IVF) is associated with reduced live birth rates compared with conventional IVF, according to a study published in the January issue of the American Journal of Obstetrics & Gynecology.

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Patient Race Linked to Failure to Achieve HbA1c Target

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Factors associated with failure to achieve a glycated hemoglobin (HbA1c) target in the standard therapy arm of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) glycemia trial have been identified, according to research published in the January issue of Diabetes, Obesity and Metabolism.

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PPARγ Antagonist Imatinib Improves Insulin Sensitivity

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation as an antagonist ligand, improving insulin sensitivity and promoting browning of white adipose tissue, according to a study published online Jan. 6 in Diabetes.

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Acute Ozone Exposure Ups Stress Hormone in Humans

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Acute ozone exposure increases stress hormones and causes alterations in peripheral lipid metabolism in humans, according to research published online Jan. 8 in the American Journal of Respiratory and Critical Care Medicine.

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Sugary Drinks Linked to Increase in Visceral Adipose Tissue

TUESDAY, Jan. 12, 2016 (HealthDay News) -- Regular consumption of sugar-sweetened beverages is associated with greater accumulation of visceral adipose tissue, according to research published online Jan. 11 in Circulation.

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Hyperbaric Oxygen Therapy No Benefit for Diabetic Foot Ulcers

TUESDAY, Jan. 12, 2016 (HealthDay News) -- For patients with diabetes and chronic diabetic foot ulcers (DFUs), hyperbaric oxygen therapy (HBOT) does not reduce indications for amputation, according to a study published online Jan. 6 in Diabetes Care.

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Reduction in Proximal, Distal Leg Muscle Strength in T2DM

MONDAY, Jan. 11, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), proximal and distal leg muscle strength is reduced, and proximal but not distal muscle volume is also reduced, according to a study published online Jan. 6 in Diabetes Care.

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FDA Approves Device for Diabetic Foot Ulcers

FRIDAY, Jan. 8, 2016 (HealthDay News) -- The Integra Omnigraft Dermal Regeneration Matrix has been approved by the U.S. Food and Drug Administration to treat diabetic foot ulcers.

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Extended-Release Niacin Lowers ApoB-48 Concentration in T2DM

FRIDAY, Jan. 8, 2016 (HealthDay News) -- For patients with type 2 diabetes, a statin plus extended-release niacin (ERN) lowers apolipoprotein B-48 (apoB-48) concentration compared to a statin alone, according to a study published online Dec. 18 in Diabetes, Obesity and Metabolism.

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New Guidelines Say Limit Added Sugars to <10 Percent of Calories

FRIDAY, Jan. 8, 2016 (HealthDay News) -- The 2015-2020 Dietary Guidelines for Americans offers five overarching guidelines that encourage healthy eating patterns, rather than focusing on individual dietary components such as food groups and nutrients as in previous editions.

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Trends in Insulin Use, Glycemic Control Explored

THURSDAY, Jan. 7, 2016 (HealthDay News) -- Since 1988, the proportion of patients with diabetes currently on any insulin has remained stable, according to research published online Dec. 30 in Diabetes Care.

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Diabetic Retinopathy Screening Varies Across Minority Groups

WEDNESDAY, Jan. 6, 2016 (HealthDay News) -- For patients with diabetes, diabetic retinopathy (DR) screening varies for different minority groups, according to research published online Dec. 30 in Diabetes Care.

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Many Patients Using E-Mail As First Method of Provider Contact

TUESDAY, Jan. 5, 2016 (HealthDay News) -- For patients with chronic conditions, the ability to communicate with their doctor via e-mail may help improve their health, according to a study published online Dec. 21 in the American Journal of Managed Care.

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Prevalence of Diabetic Macular Edema Varies by Test

TUESDAY, Jan. 5, 2016 (HealthDay News) -- Diabetic macular edema (DME) is more often diagnosed using monocular fundus photography than optical coherence tomography (OCT) central subfield thickness (CST), according to a study published online Dec. 30 in JAMA Ophthalmology.

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High Dose of Vitamin D Tied to Higher Risk of Falls in Elderly

TUESDAY, Jan. 5, 2016 (HealthDay News) -- Higher monthly doses of vitamin D have no benefit on lower extremity function and correlate with increased risk of falls compared with lower doses in elderly adults, according to a study published online Jan. 4 in JAMA Internal Medicine.

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Opioid Exposure Tied to Higher Odds of Low Testosterone Levels

MONDAY, Jan. 4, 2016 (HealthDay News) -- Exposure to opioids is associated with increased likelihood of low testosterone levels, with increased odds as age and number of comorbidities increase, according to a study published in the December issue of Pain Medicine.

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