Ivermectin Has Topical Anti-Inflammatory Properties

Share this content:
Ivermectin Has Topical Anti-Inflammatory Properties
Ivermectin Has Topical Anti-Inflammatory Properties

MONDAY, Jan. 9, 2017 (HealthDay News) -- Ivermectin (IVM) has anti-inflammatory properties that could be beneficial in treatment of T-cell mediated skin inflammatory diseases, according to an experimental study published online Jan. 4 in Allergy.

Erwan Ventre, Ph.D., from the Université de Lyon in France, and colleagues examined the activity of IVM in a murine model of atopic dermatitis induced by repeated exposure to Dermatophagoides farinae and in cellular immunology assays.

The researchers found that topical IVM correlated with improvement in allergic skin inflammation, with reduction of the priming and activation of allergen-specific T cells and the production of inflammatory cytokines. IVM had no major effect on dendritic cell functions in vivo and in vitro, but following polyclonal and antigen-specific stimulation, IVM did impair T-cell activation, proliferation, and cytokine production.

"Altogether, our results show that IVM is endowed with topical anti-inflammatory properties that could have important applications for the treatment of T-cell mediated skin inflammatory diseases," the authors write.

Several authors were employed by Galderma, which manufactures ivermectin and funded the study.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease


Sign up for myCME e-newsletters


More in Home

Walmart Launches Disposal Solution for Opioids, Rx Meds

Walmart Launches Disposal Solution for Opioids, Rx Meds

DisposeRx, available at no cost, transforms prescription drugs into non-divertible, biodegradable gel

ADHD Meds Increasingly Prescribed to Reproductive-Aged Women

ADHD Meds Increasingly Prescribed to Reproductive-Aged Women

Increase of 344 percent, from 0.9 percent of women in 2003 to 4 percent of women in 2015

Bikram Yoga Improves Vascular Health With or Without Heat

Bikram Yoga Improves Vascular Health With or Without ...

Increase in brachial artery flow-mediated dilation seen in heated and thermoneutral environment

is free, fast, and customized just for you!

Already a member?

Sign In Now »