Intraocular Pressure Down With Anesthesia in Children

This article originally appeared here.
Share this content:
Intraocular Pressure Down With Anesthesia in Children
Intraocular Pressure Down With Anesthesia in Children

THURSDAY, July 14, 2016 (HealthDay News) -- Pediatric patients undergoing general anesthesia have reductions in intraocular pressure (IOP), with the lowest IOP measured after induction of anesthesia, according to a study published online July 5 in Pediatric Anesthesia.

Julia Termühlen, from the University of Muenster Medical Center in Germany, and colleagues examined normal distribution of IOP during general anesthesia in healthy children. Participants included 100 pediatric patients with no history of glaucoma scheduled for nonintraocular surgery. The patients underwent general anesthesia induced with sevoflurane (s) or propofol (p) and maintained with sevoflurane with remifentanil (S) or propofol with remifentanil (P). Depending on the anesthetics used during induction and maintenance, the patients were grouped as sS, sP, pP, pS. Hemodynamic measures and IOP were measured before anesthesia induction (M1), in apnea immediately after induction (M2), in deep anesthesia (M3), and after extubation (M4).

The researchers observed a significant reduction in IOP with general anesthesia. The mean IOP was distributed normally (mean 7.4 ± 2.89 mm Hg at M1) and it decreased to a minimum of 5.6 ± 3.04 mm Hg at M2. Comparable decreases in IOP were seen between M1 and M2 in all groups. The IOP increased again during deep anesthesia (M3) and reversal (M4) in all groups. The sS group had a significantly lower IOP than the sP and pP groups during reversal.

"Sevoflurane and propofol, both in combination with remifentanil, significantly lower IOP in children," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

GDM Found to Increase Risk for Postpartum Depression

GDM Found to Increase Risk for Postpartum Depression

Researchers find odds up even more if woman has suffered an earlier bout of depression

Cervical Cancer Mortality Higher Among Older, Black Women

Cervical Cancer Mortality Higher Among Older, Black Women

Rates rose when latest study excluded women who'd already undergone hysterectomy

Many Advanced NSCLC Patients Not Getting Helpful Treatment

Many Advanced NSCLC Patients Not Getting Helpful Treatment

Study found 21 percent went without therapy, even though it could boost survival

is free, fast, and customized just for you!

Already a member?

Sign In Now »