Intra-Arterial Treatment Effective With Extracranial Carotid Disease

Share this content:
Intra-Arterial Treatment Effective With Extracranial Carotid Disease
Intra-Arterial Treatment Effective With Extracranial Carotid Disease

THURSDAY, June 1, 2017 (HealthDay News) -- Acute intra-arterial treatment (IAT) seems to be as effective for patients with acute ischemic stroke caused by intracranial proximal occlusion with, versus those without, extracranial carotid disease (ECD), according to research published online May 23 in the Annals of Internal Medicine.

Olvert A. Berkhemer, M.D., Ph.D., from the Academic Medical Center in Amsterdam, and colleagues conducted a prespecified subgroup analysis of a randomized clinical trial of endovascular treatment for intracranial proximal anterior circulation occlusion in 16 hospitals in the Netherlands. Participants received either IAT or no IAT.

The researchers found that the functional outcome was associated with an adjusted common odds ratio (acOR) of 1.67 (95 percent confidence interval [CI], 1.21 to 2.30) in favor of the intervention. In the prespecified subgroup of patients with ECD, the acOR was 3.1 (95 percent CI, 1.7 to 5.8), compared to 1.3 (95 percent CI, 0.9 to 1.9) in patients presenting without ECD (P for interaction = 0.07).

"Intra-arterial treatment may be at least as effective in patients with ECD as in those without ECD, and it should not be withheld in these complex patients with acute ischemic stroke," the authors write.

Several authors disclosed financial ties to biopharmaceutical companies, including AngioCare, Medtronic/Covidien/EV3, MEDAC/LAMEPRO, Penumbra, Stryker, and Top Medical/Concentric, all of which partially funded the study.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

NAFLD Linked to Smaller Total Cerebral Brain Volume

NAFLD Linked to Smaller Total Cerebral Brain Volume

Significant correlation even after adjustment for all covariates, including age, sex, alcohol consumption

Salivary miRNAs Can ID Duration of Concussion Symptoms

Salivary miRNAs Can ID Duration of Concussion Symptoms

Pediatric patients with prolonged symptoms were accurately identified by levels of five miRNAs

Treatment Trajectories Vary for Children With Depression

Treatment Trajectories Vary for Children With Depression

Most common class got psychotherapy monotherapy, and had lowest incidence of attempted suicide

is free, fast, and customized just for you!

Already a member?

Sign In Now »