International Variation in Prevalence of Celiac in T1DM

Share this content:
International Variation in Prevalence of Celiac in T1DM
International Variation in Prevalence of Celiac in T1DM

THURSDAY, July 13, 2017 (HealthDay News) -- Celiac disease (CD) is a common comorbidity in young people with type 1 diabetes, and the prevalence appears to vary internationally, according to a study published online June 29 in Diabetes Care.

Maria E. Craig, M.B.B.S., Ph.D., from the Children's Hospital at Westmead in Sydney, and colleagues examined international differences in CD prevalence and characteristics of children with coexisting type 1 diabetes and CD versus type 1 diabetes only. Data were included for 52,721 young people aged <18 years.

The researchers found that 3.5 percent of young people had biopsy-confirmed CD, which was diagnosed at a median age of 8.1 years. The prevalence of CD ranged from 1.9 to 7.7 percent in the U.S. T1D Exchange Clinic Network and Australasian Diabetes Data Networks, respectively; prevalence was higher for girls than boys (4.3 versus 2.7 percent; P < 0.001). Compared to those with type 1 diabetes only, children with coexisting CD were younger at diabetes diagnosis (5.4 versus 7.0 years; P < 0.001) and fewer were non-white (15 versus 18 percent; P < 0.001). Those with CD had lower height standard deviation score (0.36 versus 0.48; adjusted P < 0.001), and fewer were overweight/obese (34 versus 37 percent; adjusted P < 0.001). The mean hemoglobin A1c values were comparable (8.3 ± 1.5 versus 8.4 ± 1.6 percent).

"Differences in CD prevalence may reflect international variation in screening and diagnostic practices, and/or CD risk," the authors write.

One author disclosed holding an equity fund that may contain stock from pharmaceutical companies.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Automated Central System Offers Time Savings for Pharmacists

Automated Central System Offers Time Savings for Pharmacists

Cart-fill process using new automated system is more efficient, frees up time for other roles

Therapeutic Horseback Riding Can Help Alleviate PTSD in Veterans

Therapeutic Horseback Riding Can Help Alleviate PTSD in ...

Study found statistically and clinically significant reduction in PTSD scores after six weeks of THR

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Six-year antidiabetes treatment initiation rate also much lower after bariatric surgery

is free, fast, and customized just for you!

Already a member?

Sign In Now »