Increased VTE Risk for Men Starting Testosterone Therapy

Share this content:
Increased VTE Risk for Men Starting Testosterone Therapy
Increased VTE Risk for Men Starting Testosterone Therapy

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Starting testosterone treatment is associated with an increased risk of venous thromboembolism (VTE), peaking within six months and declining thereafter, according to a study published online Nov. 30 in The BMJ.

Carlos Martinez, M.D., of the Institute for Epidemiology, Statistics and Informatics in Frankfurt, Germany, and colleagues reviewed data from 19,215 British patients with confirmed VTE. These men were compared with 909,530 age-matched patients in a control group.

Within the first six months of testosterone treatment, the rate ratio of VTE was 1.63 compared to those not taking the hormone, the researchers found. The rate ratios after more than six months' treatment and treatment cessation were 1.00 and 0.68, respectively.

"Our study suggests a transient increase in the risk of VTE that peaks during the first three to six months and declines gradually thereafter. Failure to investigate the timing of VTEs in relation to the duration of testosterone use could result in masking of an existing transient association," the authors write. "Future research is needed to confirm this temporal increase in the risk of VTE and to investigate the risk in first-time testosterone users and confirm the absence of risk with long-term use."

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Gene Tx Approved for Certain Types of B-Cell Lymphoma

Gene Tx Approved for Certain Types of B-Cell ...

First such treatment for certain types of non-Hodgkin lymphoma

Uninsurance Down by One-Third for Cancer Diagnoses in 2014

Uninsurance Down by One-Third for Cancer Diagnoses in ...

Significant decreases in uninsurance seen across all stages and sites assessed in first year of ACA

Diabetes Ups Risk of MACE in Acute Coronary Syndromes

Diabetes Ups Risk of MACE in Acute Coronary ...

Diabetes, but not pre-diabetes, tied to increased risk of major adverse cardiac events in adjusted model

is free, fast, and customized just for you!

Already a member?

Sign In Now »