Increase in HPV Prevalence Seen After Renal Transplant in Women

Share this content:
Increase in HPV Prevalence Seen After Renal Transplant in Women
Increase in HPV Prevalence Seen After Renal Transplant in Women

THURSDAY, Dec. 29, 2016 (HealthDay News) -- An increase in human papillomavirus (HPV) prevalence after renal transplantation (RT) may result from reactivation of latent HPV infections in women, according to a study published online Dec. 23 in the American Journal of Transplantation.

Floor Hinten, M.D., from the Radboud University Medical Center in the Netherlands, and colleagues assessed the prevalence of genital HPV before and after RT in 65 female patients. Gynecological examination was performed at first visit, as well as one and two years later. Every three months, HPV self-sampling and questionnaires on sexual behavior were performed.

The researchers found that high-risk HPV (hrHPV) increased significantly from 19 percent before RT to 31 percent after RT (P = 0.045) with the highly sensitive SPF10-LiPA25 test and increased from 10 percent before to 14 percent after RT (P = 0.31) with the Cobas 4800 HPV test. No changes in sexual behavior were reported during follow-up. Among 33 patients who were counseled, but did not undergo RT, the hrHPV prevalence was 21 percent at study entry and 27 percent after 12 months using the sensitive test; prevalence held stable at 16 percent with the clinically validated Cobas test.

"The results of this study indicate that activation of latent HPV infections may contribute to the increased risk of HPV-related (pre)malignant lesions in female renal transplant recipients," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ASA: Class-Specific Link Between Periodontal Disease and Stroke

ASA: Class-Specific Link Between Periodontal Disease and Stroke

Link strongest for thrombotic strokes, cardioembolic strokes

ASA: Not Enough Stroke Patients Being Treated With tPA

ASA: Not Enough Stroke Patients Being Treated With ...

Minorities, women, seniors on Medicare, rural residents less likely to be diagnosed in time for tPA

Cytomegalovirus May Up Risk of Diabetes, CVD in Some Women

Cytomegalovirus May Up Risk of Diabetes, CVD in ...

Conversely, for women with extreme obesity, CMV may offer protection against CVD, DM

is free, fast, and customized just for you!

Already a member?

Sign In Now »