Hypoglycemia, Bradycardia Up in Neonates Exposed to β-Blockers

Share this content:
Hypoglycemia, Bradycardia Up in Neonates Exposed to β-Blockers
Hypoglycemia, Bradycardia Up in Neonates Exposed to β-Blockers

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Neonates born to mothers exposed to β-blockers at the time of delivery have increased risk of neonatal hypoglycemia and bradycardia, according to a study published in online Aug. 30 in Pediatrics.

Brian T. Bateman, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from 2,292,116 completed pregnancies linked to live-born infants of Medicaid-enrolled women from 2003 to 2007 to examine the risks of neonatal hypoglycemia and neonatal bradycardia associated with maternal exposure to β-blockers. The authors controlled for potential confounders using propensity score matching.

The researchers identified 10,585 pregnancies that were exposed to β-blockers at the time of delivery. The risk of neonatal hypoglycemia was 4.3 and 1.2 percent in the β-blocker-exposed and unexposed neonates, respectively. Risk remained elevated for neonatal hypoglycemia and bradycardia among exposed versus unexposed pregnancies after adjustment for confounders (adjusted odds ratios, 1.68 and 1.29, respectively).

"Our findings suggest that neonates born to mothers exposed to β-blockers in late pregnancy, including labetalol, are at elevated risk for neonatal hypoglycemia and bradycardia," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

FDA Approves First Drug for Rare Form of Rickets

FDA Approves First Drug for Rare Form of ...

Crysvita approved for adults and children ages 1 year and older with x-linked hypophosphatemia

High FGF-23 Linked to Recurrent Cardiac Events After ACS

High FGF-23 Linked to Recurrent Cardiac Events After ...

FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization

Medical Cannabis Not Recommended for Sleep Apnea

Medical Cannabis Not Recommended for Sleep Apnea

American Academy of Sleep Medicine says evidence insufficient to recommend cannabis for apnea

is free, fast, and customized just for you!

Already a member?

Sign In Now »