Hyperglycemia Tied to Outcomes in Pediatric Stroke

This article originally appeared here.
Share this content:
Hyperglycemia Tied to Outcomes in Pediatric Stroke
Hyperglycemia Tied to Outcomes in Pediatric Stroke

TUESDAY, May 24, 2016 (HealthDay News) -- For children with arterial ischemic stroke, infarct volume and hyperglycemia, but not hypertension and fever, correlate with poor neurological outcome, according to research published online May 23 in JAMA Neurology.

Kimberly N. Grelli, M.D., from the University of Washington in Seattle, and colleagues performed a retrospective review of children aged 29 days to 18 years with their first arterial ischemic stroke. Blood pressure, blood glucose, and temperature data were collected for five days after stroke for 98 children (median age, 6.0 years; 59.2 percent male) identified with stroke.

The researchers found that 65.3 percent of children had hypertension, 68.4 percent had hypotension, 18.1 percent had hyperglycemia, and 37.8 percent had fever. An infarct size of 4 percent or greater of brain volume had the greatest association with poor neurological outcome (odds ratio, 5.6; P = 0.01). There was an independent correlation for hyperglycemia with poor neurological outcome (odds ratio, 3.9: P = 0.02). No significant correlations were seen for hypertension and fever with infarct size, poor outcome, or death. At three-month follow-up, hypertension was not documented in 27.6 percent of surviving children, and was not associated with poor neurological outcome.

"Prospective studies that systematically record blood pressure, blood glucose, and temperature data are required to further assess the associations between these potentially modifiable physiological parameters and pediatric stroke outcome," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Dietary changes, other meds, and even surgery can lower cardiovascular risk similarly to statins

Negative Effects Seen With Video Gaming 9 Hours/Week

Negative Effects Seen With Video Gaming 9+ Hours/Week

Benefits seen with one hour a week, but behavioral problems appear to rise at nine hours a week

Improved Adult Lung Function Linked to Childhood Farm Life

Improved Adult Lung Function Linked to Childhood Farm ...

First study to report beneficial effects of growing up on a farm on adult FEV1

is free, fast, and customized just for you!

Already a member?

Sign In Now »