HMI Impulses From Ultrasound Transducer Beneficial in STEMI

Share this content:
HMI Impulses From Ultrasound Transducer Beneficial in STEMI
HMI Impulses From Ultrasound Transducer Beneficial in STEMI

FRIDAY, May 27, 2016 (HealthDay News) -- High mechanical index (HMI) impulses from a diagnostic ultrasound (DUS) transducer during intravenous microbubble infusion can prevent microvascular obstruction in ST-segment elevation myocardial infarction (STEMI), according to a study published in the May 31 issue of the Journal of the American College of Cardiology.

Wilson Mathias Jr., M.D., from the University of São Paulo Medical School in Brazil, and colleagues randomized patients arriving with their first STEMI to DUS intermittent HMI impulses just before and after emergent percutaneous coronary intervention (PCI) (HMI + PCI; 20 patients) or to low mechanical index (LMI) imaging before and after PCI (LMI + PCI; 10 patients). Seventy patients arrived outside the time window of ultrasound availability and received PCI only.

The researchers found that the median door-to-dilation times did not differ significantly between the groups. Angiographic recanalization prior to PCI occurred in 60, 10, and 23 percent of the HMI + PCI, LMI + PCI, and PCI-only groups, respectively (P = 0.002). No differences were seen in microvascular obstructed segments prior to treatment; at one month there were significantly smaller proportions of obstructed segments in the HMI + PCI group (P = 0.001) and significant improvements in left ventricular ejection fraction (P < 0.005).

"HMI impulses from a diagnostic transducer, combined with a commercial microbubble infusion, can prevent microvascular obstruction and improve functional outcome when added to the contemporary PCI management of acute STEMI," the authors write.

Two authors disclosed financial ties to the pharmaceutical and medical device industries.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

High Success Rates for Mitral Valve Repair With Robotic Surgery

High Success Rates for Mitral Valve Repair With ...

Minimally invasive surgery linked to fewer discharges to facility, one day less in hospital vs conservative sx

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants

Rates of Cardiac Stress Testing Down but Still Higher in CKD

Rates of Cardiac Stress Testing Down but Still ...

Decline in rates of cardiac stress testing in Medicare beneficiaries aged ≥66 years from 2008 to 2012

is free, fast, and customized just for you!




Already a member?

Sign In Now »