High-Intensity Focused U/S With Cooling Destroys Adipocytes

This article originally appeared here.
Share this content:
High-Intensity Focused U/S With Cooling Destroys Adipocytes
High-Intensity Focused U/S With Cooling Destroys Adipocytes

MONDAY, Aug. 29, 2016 (HealthDay News) -- A novel high-intensity focused ultrasound (HIFU) treatment with a cooling system is safe and efficient for destroying adipocytes, according to a study published online Aug. 23 in Lasers in Surgery and Medicine.

Heun Joo Lee, M.D., from the University of Ulsan College of Medicine in Seoul, South Korea, and colleagues conducted a series of four HIFU treatments with or without contact cooling on three pigs over a period of 12 weeks. Treatment with the HIFU device with cooling was also administered to three human volunteers.

The researchers found that HIFU with contact cooling reduced skin surface temperature and prevented damage to the epidermis. Immediately after HIFU treatment, ecchymosis was observed on the non-cooled area, but not on the cooled area. Disrupted adipocytes were revealed in the treatment area in histological analyses of both cooled and non-cooled areas immediately and at one and four weeks after treatment. At four weeks there was evidence of lipophagic histiocytic fat necrosis. All inflammation subsided at 12 weeks, and the lobules were markedly atrophied with reduced thickness of subcutaneous adipose tissue. After four weeks, human volunteers experienced reduction of a few centimeters in waist circumference. The pain was tolerable without bruising.

"This novel HIFU device with an added contact cooling system may provide an effective, safe and less painful treatment as a non-invasive device for fat reduction," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

900 Steps Tied to Functional Decline in Hospitalized Seniors

<900 Steps Tied to Functional Decline in Hospitalized ...

Walking <900 steps/day linked to hospitalization-associated functional decline

Thromboprophylaxis Not Effective After Knee Arthroplasty, Casting

Thromboprophylaxis Not Effective After Knee Arthroplasty, Casting

Does not prevent venous thromboembolism after knee arthroplasty, casting of lower leg

ASH: Lower Rate of Sickle Cell Pain Crises With Crizanlizumab

ASH: Lower Rate of Sickle Cell Pain Crises ...

Lower rate of crises per year; longer median time to first, second crises with high-dose therapy

is free, fast, and customized just for you!

Already a member?

Sign In Now »