High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

Share this content:
High CVD Risk in Patients With Head, Neck Squamous Cell Cancer
High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Twenty-three percent of patients with head and neck squamous cell carcinoma (HNSCC) have cardiovascular disease (CVD) at diagnosis, and 24 percent have uncontrolled blood pressure, according to research published online Dec. 29 in Head & Neck.

Christian C. Okoye, M.D., from Case Western Reserve University in Cleveland, and colleagues retrospectively reviewed patients with HNSCC who underwent definitive or adjuvant (chemo)radiation between 2011 and 2013. The authors calculated the 10-year risk estimates for a cardiovascular disease event according to the Framingham Risk Score (FRS).

One hundred fifteen patients with mainly stage III/IV HNSCC were followed up for a median of two years. The researchers found that 23 percent of patients had CVD at diagnosis. Patients with laryngeal cancer had higher FRS than those with cancer at other sites (20.5 versus 14.4 percent). At diagnosis, 24 percent of all patients had uncontrolled blood pressure. Forty-one and 30 percent of patients with CVD were not taking antiplatelet therapy or statin therapy, respectively. Indications for initiating statin therapy were seen for 34 percent of patients with CVD.

"Patients with HNSCC have a high baseline CVD risk and many do not receive optimal preventive care," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Opioid Rx, Dosing Often Excessive in Dialysis Patients

Opioid Rx, Dosing Often Excessive in Dialysis Patients

High-risk dialysis population also subject to the risks of long-term opioid use

Nonadherence to Statins  ACEIs/ARBs Risky Post MI

Nonadherence to Statins + ACEIs/ARBs Risky Post MI

Adherence to beta-blockers may not be as beneficial to patients after myocardial infarction

Pulse Ox  Auscultation Reliable for Congenital Heart Screening

Pulse Ox + Auscultation Reliable for Congenital Heart ...

The method significantly improves detection rate of major CHD in newborns

is free, fast, and customized just for you!

Already a member?

Sign In Now »