Glycolic Peel Enhances Azelaic Acid in Melasma Treatment

This article originally appeared here.
Share this content:
Glycolic Peel Enhances Azelaic Acid in Melasma Treatment
Glycolic Peel Enhances Azelaic Acid in Melasma Treatment

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Glycolic acid (GA) peel enhances the therapeutic efficacy of topical azelaic acid (AA) cream for treatment of melasma, according to a study published online Aug. 8 in the Journal of Cosmetic Dermatology.

Surabhi Dayal, M.D., from the Sharma Post Graduate Institute of Medical Sciences in Rohtak, India, and colleagues assessed the clinical efficacy and safety of glycolic peel in conjunction with topical AA for treatment of melasma. Over 24 weeks, 60 patients received either serial GA peel every three weeks with twice-daily 20 percent AA cream or only 20 percent AA cream (control group).

The researchers found that improvement in Melasma Area Severity Index (MASI) and percentage decrease in MASI scoring were statistically significant 12 weeks and beyond in the study group versus the control group. There was also a significant improvement in melasma quality of life scores after treatment in the study group versus the control group. Both groups had minor reversible side effects, which did not require cessation of therapy.

"GA peel enhances therapeutic efficacy of topical AA cream for treatment of melasma, with improvement in quality of life without serious side effects," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

ASCO: Moderate Activity Tied to Longer Survival in Advanced CRC

ASCO: Moderate Activity Tied to Longer Survival in ...

Patients only appeared to derive benefit from moderate -- not vigorous -- activity

Number of Infants Born to Women Using Opioids Up Sharply

Number of Infants Born to Women Using Opioids ...

Few treatment programs deal with substance abuse in expectant moms, federal report says

Hypertension Onset After Age 80 May Protect Against Dementia

Hypertension Onset After Age 80 May Protect Against ...

Association independent of antihypertensive medication use

is free, fast, and customized just for you!

Already a member?

Sign In Now »