Gene Associated With Risk of Acute Otitis Media

Share this content:
Gene Associated With Risk of Acute Otitis Media
Gene Associated With Risk of Acute Otitis Media

TUESDAY, Oct. 11, 2016 (HealthDay News) -- A potential genetic link to a child's higher risk of acute otitis media has been identified, according to research published online Sept. 28 in Nature Communications.

The analysis of DNA samples from 13,000 children revealed a link between acute otitis media and a site on chromosome 6 that contains the gene FNDC1. Follow-up studies showed that the corresponding gene in mice was expressed in the middle ear.

"Although the gene's function in humans has not been well studied, we do know that FNDC1 codes for a protein with a role in inflammation," said study leader Hakon Hakonarson, M.D., Ph.D., director of the Center for Applied Genomics at The Children's Hospital of Philadelphia.

"Although microbes cause this condition, it's been well-known that genetics also plays a role," he said in a hospital news release. "This is the first and largest genetic study focused on risk susceptibility for acute otitis media."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

Synthetic product made from purified human hemoglobin proteins coated with a synthetic polymer

Fewer School Shootings in States With Tighter Gun Laws

Fewer School Shootings in States With Tighter Gun ...

Study also found that states that spent more money on mental health care, education saw less violence

SABCS: No Survival Benefit Seen for Letrozole Beyond Five Years

SABCS: No Survival Benefit Seen for Letrozole Beyond ...

Study found women who continued with letrozole did experience other benefits, however

is free, fast, and customized just for you!

Already a member?

Sign In Now »