Fibromyalgia Symptoms Improve With CoQ10 Supplementation

Share this content:
Fibromyalgia Symptoms Improve With CoQ<sub>10</sub> Supplementation
Fibromyalgia Symptoms Improve With CoQ10 Supplementation

FRIDAY, Jan. 6, 2017 (HealthDay News) -- For patients with fibromyalgia (FM), coenzyme Q10 (CoQ10) supplementation is associated with improvement in clinical symptoms, according to a letter to the editor published online Jan. 4 in CNS Neuroscience & Therapeutics.

Elísabet Alcocer-Gómez, from the University of Sevilla in Spain, and colleagues compared the effect of CoQ10 with placebo supplementation in psychopathological profiles from patients with FM. Twenty patients diagnosed with FM were recruited and randomized in a 1:1 ratio to CoQ10 or placebo for 40 days.

The researchers observed no changes in body mass index among the patients after 40 days. The CoQ10 group had molecular changes, including increment in mitochondrial biogenesis and antioxidants gene expression, and reduction in inflammation. These were accompanied by improvement in clinical symptoms determined by Fibromyalgia Impact Questionnaire, Pittsburgh Sleep Quality Index, and tender points. A clinically significant improvement was seen in all subscores from the Symptom Checklist-90-R, with statistically significant reduction in interpersonal sensitivity, depression, anxiety, hostility, and psychoticism items (all P < 0.001); moderately significant changes were seen in somatization and obsessive-compulsive items (both P < 0.05).

"Further analysis involving more patients in double-blind placebo-controlled clinical trials is required to confirm these observations," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Illicit Marijuana Use Up in States With Legal Medical Use

Illicit Marijuana Use Up in States With Legal ...

Cannabis use disorder is also rising faster in states with legalization laws

Chromosome Instability Test Prognostic in NSCLC

Chromosome Instability Test Prognostic in NSCLC

Chromosome instability associated with higher risk of relapse, death within 2 years

CDC: Opioid-Related Mortality Rate Might Be Underestimated

CDC: Opioid-Related Mortality Rate Might Be Underestimated

Death certificates from drug-linked infections may not label opioids as possible cause

is free, fast, and customized just for you!

Already a member?

Sign In Now »