Fewer Self-Injury Events With Lithium for Bipolar Disorder

This article originally appeared here.
Share this content:
Fewer Self-Injury Events With Lithium for Bipolar Disorder
Fewer Self-Injury Events With Lithium for Bipolar Disorder

FRIDAY, May 13, 2016 (HealthDay News) -- Patients with bipolar disorder taking lithium have lower rates of self-harm and unintentional injury compared to those taking other mood stabilizers, according to research published online May 11 in JAMA Psychiatry.

Joseph Hayes, M.B., Ch.B., fellow of psychiatry at University College London, and colleagues collected medical data on 6,671 patients diagnosed with bipolar disorder and prescribed only one of the following drugs: lithium, valproate, olanzapine, or quetiapine.

The investigators found that patients on lithium were less likely to harm themselves, either intentionally or by accident. Patients taking one of the alternative mood stabilizers were 40 percent more likely to harm themselves compared to patients on lithium. Patients on valproate or quetiapine were 32 to 34 percent more likely to experience unintentional injury, most likely while experiencing a manic episode. The suicide rate was lower in the lithium group, but too few suicides occurred to allow accurate risk estimates.

"This is important because people with bipolar disorder are 15 times more likely to die by suicide and six times more likely to die by accidental injury than the general population," Hayes told HealthDay.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Maintenance Intervention Improves Long-Term Weight Loss

Maintenance Intervention Improves Long-Term Weight Loss

Coaching sessions seem to help patients keep from regaining the weight

AAN: Mercury in Seafood May Be Tied to Higher Risk of ALS

AAN: Mercury in Seafood May Be Tied to ...

Certain types of seafood may be linked to the disease, early research suggests

Patients With Opioid Addiction Benefit From Tx Initiated in ER

Patients With Opioid Addiction Benefit From Tx Initiated ...

Giving drugs to reduce cravings appears to be effective option, researchers find

is free, fast, and customized just for you!

Already a member?

Sign In Now »