FDA Approves Vistogard to Treat Chemotherapy Overdose

Share this content:
FDA Approves Vistogard to Treat Chemotherapy Overdose
FDA Approves Vistogard to Treat Chemotherapy Overdose

FRIDAY, Dec. 11, 2015 (HealthDay News) -- Vistogard (uridine triacetate) has been approved by the U.S. Food and Drug Administration to treat an overdose of the chemotherapy drugs fluorouracil and capecitabine, commonly used to treat cancers of the breast and gastrointestinal tract.

Treatment with Vistogard should begin as soon as possible after the overdose, even if any symptoms of overdose aren't present, the agency warned. The user's doctor should then determine when a return to chemotherapy is appropriate.

Vistogard is designed to minimize cell damage caused by chemotherapy. The drug was evaluated in clinical studies involving 135 children and adults who either had taken an overdose of chemotherapy or had developed a life-threatening toxic reaction within 96 hours of being given chemotherapy. Of clinical trial participants given Vistogard, 89 to 97 percent were still alive after 30 days, the agency said.

Vistogard is not recommended for non-emergency adverse reactions associated with chemotherapy, as the new drug could weaken the effects of chemotherapy, the FDA said. Vistogard's most common side effects included diarrhea, vomiting, and nausea.

Vistogard is marketed by Gaithersburg, Md.-based Wellstat Therapeutics.

More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Disabling Injury, Illness Less Likely for Elderly Who Exercise

Disabling Injury, Illness Less Likely for Elderly Who ...

And likely to recover more quickly if injury or illness occurs

More Evidence of Abdominal Fat, Poor Cardiovascular Health Link

More Evidence of Abdominal Fat, Poor Cardiovascular Health ...

Adipose tissue imaging may outperform body mass index for cardiovascular risk assessment

is free, fast, and customized just for you!

Already a member?

Sign In Now »