FDA Approves New Parkinson's Add-On Drug Xadago

Share this content:
FDA Approves New Parkinson's Add-On Drug Xadago
FDA Approves New Parkinson's Add-On Drug Xadago

WEDNESDAY, March 22, 2017 (HealthDay News) -- Xadago (safinamide) tablets have been approved by the U.S. Food and Drug Administration as an add-on drug to treat Parkinson's patients who take levodopa or carbidopa but experience "off" episodes.

Xadago's effectiveness was established in a clinical study of 645 patients who were taking levodopa but were still having "off" periods. Compared to patients who took a placebo, users of Xadago had fewer instances of Parkinson's symptoms.

Certain patients shouldn't take Xadago, including those with severe liver problems and those taking dextromethorphan, monoamine oxidase inhibitors, or certain antidepressants, the FDA said.

Xadago's most common side effects included involuntary movement, falls, nausea, and insomnia. More serious adverse reactions included worsening hypertension, falling asleep during daily activities, hallucinations, psychotic and/or compulsive behavior, fever, and confusion.

The FDA granted approval of Xadago to Newron Pharmaceuticals, based in Milan.

More Information

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

High Success Rates for Mitral Valve Repair With Robotic Surgery

High Success Rates for Mitral Valve Repair With ...

Minimally invasive surgery linked to fewer discharges to facility, one day less in hospital vs conservative sx

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants

Rates of Cardiac Stress Testing Down but Still Higher in CKD

Rates of Cardiac Stress Testing Down but Still ...

Decline in rates of cardiac stress testing in Medicare beneficiaries aged ≥66 years from 2008 to 2012

is free, fast, and customized just for you!




Already a member?

Sign In Now »