Fat-Free Mass Index Predicts Survival in Pulmonary Fibrosis

Share this content:
Fat-Free Mass Index Predicts Survival in Pulmonary Fibrosis
Fat-Free Mass Index Predicts Survival in Pulmonary Fibrosis

WEDNESDAY, Nov. 23, 2016 (HealthDay News) -- For patients with idiopathic pulmonary fibrosis (IPF), fat-free mass index (FFMI) predicts survival, according to a study published online Nov. 21 in Respirology.

Osamu Nishiyama, M.D., Ph.D., from Kindai University in Osaka, Japan, and colleagues examined whether FFMI predicts survival in 44 patients with IPF. Direct segmental multi-frequency bioelectrical impedance analysis was used to assess body composition. The authors examined the degree of correlation between variables of body composition and other variables with survival during a mean observation period of 837.5 ± 407.5 days.

The researchers identified positive correlations for FFMI with forced vital capacity (FVC), diffusion capacity of the lung for carbon monoxide (DLCO), and six-minute walk distance; a negative correlation was seen for age. No significant correlation was seen for FFMI and percentage predicted FVC or DLCO, with a similar degree of correlation noted as seen with body mass index (BMI). In univariate analysis, several variables, but not BMI, correlated significantly with survival. In a multivariate model, FFMI and percentage predicted FVC were significant factors (hazard ratios, 0.64 and 0.96, respectively).

"We conclude that FFMI is a significant independent predictor of survival in patients with IPF," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »