Exercise Intervention Doesn't Improve Walking Ability in PAD

Share this content:
Exercise Intervention Doesn't Improve Walking Ability in PAD
Exercise Intervention Doesn't Improve Walking Ability in PAD

TUESDAY, April 24, 2018 (HealthDay News) -- For patients with peripheral artery disease (PAD), a home-based exercise intervention does not improve walking ability over nine months compared with usual care, according to a study published in the April 24 issue of the Journal of the American Medical Association.

Mary M. McDermott, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues conducted a trial involving patients with PAD who were randomized to either home-based exercise (99 patients) or usual care (101 patients) for nine months. The home-based exercise intervention comprised four weekly medical center visits during the first month, followed by eight months consisting of a wearable activity monitor and telephone coaching. Overall, 91 percent of patients completed the nine-month follow-up.

The researchers found that the mean change from baseline to nine-month follow-up in the six-minute walk distance was 5.5 versus 14.4 m in the intervention and usual care groups, respectively (difference, −8.9 m; 95 percent confidence interval, −26.0 to 8.2 m; P = 0.31). The Patient-Reported Outcomes Measurement Information System pain interference score was worsened in the exercise intervention group (mean change from baseline to nine months, 0.7 versus −2.8 in the intervention versus usual care group; difference 3.5; 95 percent confidence interval, 1.3 to 5.8; P = 0.002).

"These results do not support home-based exercise interventions of wearable devices and telephone counseling without periodic onsite visits to improve walking performance in patients with PAD," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry; one author had a patent pending regarding a method to measure ankle brachial index.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Some California Mosquitoes Can Carry Zika Virus

Some California Mosquitoes Can Carry Zika Virus

Aedes aegypti mosquitoes found to transmit Zika virus

Periodontal Inflammation a Risk With Tongue Piercing

Periodontal Inflammation a Risk With Tongue Piercing

And, two young females with tongue piercings have deep lingual infrabony lesions, periodontitis

Risk of OD Highest for First Days of Opioid  Benzodiazepine Use

Risk of OD Highest for First Days of ...

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

is free, fast, and customized just for you!




Already a member?

Sign In Now »