Endoscopic Sinus Sx Ups Asthma QOL in Rhinosinusitis + Asthma

This article originally appeared here.
Share this content:
Endoscopic Sinus Sx Ups Asthma QOL in Rhinosinusitis + Asthma
Endoscopic Sinus Sx Ups Asthma QOL in Rhinosinusitis + Asthma

MONDAY, Sept. 26, 2016 (HealthDay News) -- Patients with chronic rhinosinusitis (CRS) undergoing endoscopic sinus surgery (ESS) experience improvements in asthma quality-of-life (QOL) and asthma control, according to a study published online Sept. 17 in Allergy.

Rodney J. Schlosser, M.D., from the Medical University of South Carolina in Charleston, and colleagues conducted a prospective study involving 86 patients with CRS, with and without polyps and comorbid asthma. Participants completed the Mini-Asthma QOL Questionnaire (miniAQLQ) and Asthma Control Test (ACT) at baseline and six months postoperatively.

The researchers found that patients undergoing ESS reported improved scores on the miniAQLQ (P = 0.002) and ACT (P = 0.025). Fifty-one percent of patients undergoing ESS had uncontrolled baseline asthma; for these patients, ESS resulted in a minimal clinically important difference 57 and 50 percent of the time for miniAQLQ scores and ACT scores, respectively. Baseline miniAQLQ scores were worse in patients with comorbid allergy and chronic obstructive pulmonary disease (COPD), while baseline ACT scores were worse for patients with COPD. Preoperative corticosteroid dependency and change in total 22-item SinoNasal Outcome Test score were associated with changes in miniAQLQ scores after ESS (P = 0.011 and 0.010, respectively). Obstructive sleep apnea was associated with significantly less improvement in ACT scores (P = 0.016).

"Approximately half of patients with uncontrolled asthma improve after ESS, yet there are few CRS-specific factors associated with asthma QOL or control or ESS outcomes," the authors write.

Two authors disclosed financial ties to the medical device and medical technology industries.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Naloxone Price Hikes Could Affect Rates of Opioid-Related Deaths

Naloxone Price Hikes Could Affect Rates of Opioid-Related ...

Investigators identify strategies for ensuring the drug's availability

Suicide Risk Up for Patients With Acute Coronary Syndrome

Suicide Risk Up for Patients With Acute Coronary ...

Findings underscore importance of depression screening, researcher says

SABCS: Molecular Changes Occur When Breast CA Spreads to Brain

SABCS: Molecular Changes Occur When Breast CA Spreads ...

Finding might lead to better treatment, researchers say

is free, fast, and customized just for you!

Already a member?

Sign In Now »